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Optical coherence tomography method for layering retinal images

A technology of optical coherence tomography and retinal layer, which is applied in image analysis, image enhancement, image data processing, etc., can solve the problem of unsatisfactory retinal image layering effect and achieve a good effect of layering processing

Active Publication Date: 2018-10-02
SHANGHAI INST OF OPTICS & FINE MECHANICS CHINESE ACAD OF SCI
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Problems solved by technology

The retinal layering method based on image grayscale and grayscale gradient performs simple denoising processing, and then performs retinal layering through the intensity peak on A-scan, and has a layering effect on retinal images with low contrast and complex structures such as blood vessels. not ideal

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  • Optical coherence tomography method for layering retinal images
  • Optical coherence tomography method for layering retinal images
  • Optical coherence tomography method for layering retinal images

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Embodiment Construction

[0041] The present invention will be further described below in conjunction with the embodiments and accompanying drawings, but the protection scope of the present invention should not be limited thereby.

[0042] see figure 1 , figure 1 It is a schematic diagram of the structure of the fiber-optic frequency-domain optical coherence tomography system. It includes a low-coherence light source 1, an isolator 2 is placed in the direction of the output beam of the low-coherence light source, the output end of the isolator is connected to a port 31 of a coupler 3, and the coupler 3 divides the light into a reference arm optical path 4 and a sample arm Optical path 5, the output light from port 33 of the coupler 3 passes through the collimating lens 41 of the reference arm and then irradiates on the reference plane mirror 42, and the output light from port 34 of the coupler 3 passes through the collimating lens 51 of the sample arm and then passes through the two-dimensional scanni...

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Abstract

A method of layering optical coherence tomography (OCT) retinal images. First, the image is denoised and pre-processed, and then a variable threshold is set for each A-scan image to perform layer-by-layer segmentation as the preliminary layering result. The continuity and integrity of the preliminary stratification results of each layer are judged, and the segmentation points that do not meet the requirements are corrected, so as to stratify the OCT retinal image accurately and efficiently. The advantage of the present invention is that it can perform good layering processing on OCT retinal images with high noise, low contrast, and even complex structures such as blood vessels, and effectively reduces the impact of selecting a single threshold and high speckle noise on the retinal layering effect.

Description

technical field [0001] The present invention relates to optical coherence tomography (Optical Coherence Tomography, OCT for short) images, in particular to a method for layering retinal images of optical coherence tomography. Background technique [0002] Optical coherence tomography (OCT) is a non-invasive high-resolution biomedical optical imaging technology that can detect microstructures inside biological tissues in vivo, and has been widely used in the field of ophthalmic retinal imaging. Quantitative measurement of the total thickness of retinal layers and some specific layers such as retinal nerve fiber layer (RNFL) thickness can be applied to the diagnosis of highly blinding ophthalmic diseases such as glaucoma and diabetic retinopathy. Compared with artificial retina layering, which is time-consuming and has limited accuracy, automatic retinal layering methods can improve layering efficiency and accuracy at the same time. [0003] There is a retina layering method ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G06T7/00G06T5/00
CPCG06T7/0014G06T2207/20168G06T2207/30041G06T2207/10101G06T5/70
Inventor 贺琪欲李中梁王向朝卢宇
Owner SHANGHAI INST OF OPTICS & FINE MECHANICS CHINESE ACAD OF SCI
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