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37 results about "Retina Layer" patented technology

The tissue that constitutes the retina. It is composed of the following layers: ganglion cell layer, inner limiting membrane, inner nuclear layer, inner plexiform layer, layer of the ophthalmic nerve fibers, layer of the rods and cones, neural retina, outer limiting membrane, outer nuclear layer, outer plexiform layer, and retinal pigment epithelium.

Pattern analysis of retinal maps for the diagnosis of optic nerve diseases by optical coherence tomography

Methods for analyzing retinal tomography maps to detect patterns of optic nerve diseases such as glaucoma, optic neuritis, anterior ischemic optic neuropathy are disclosed in this invention. The areas of mapping include the macula centered on the fovea, and the region centered on the optic nerve head. The retinal layers that are analyzed include the nerve fiber, ganglion cell, inner plexiform and inner nuclear layers and their combinations. The overall retinal thickness can also be analyzed. Pattern analysis are applied to the maps to create single parameter for diagnosis and progression analysis of glaucoma and optic neuropathy.
Owner:USC STEVENS UNIV OF SOUTHERN CALIFORNIA

Multi-phasic microphotodiode retinal implant and adaptive imaging retinal stimulation system

An artificial retina device and a retinal stimulation system and method for stimulating and modulating its function is disclosed. The artificial retina device includes multi-phasic microphotodiode subunits. In persons suffering from blindness due to outer retinal layer damage, a plurality of such devices, when surgically implanted into the subretinal space, may allow useful formed artificial vision to develop. By projecting real or computer controlled visible light images, and computer controlled infrared light images or illumination, simultaneously or in rapid alternation onto the artificial retina device, the nature of induced retinal images may be modulated and improved. The retinal stimulation system may be worn as a headset. Color images may be induced by programming the stimulating pulse durations and frequencies of the stimulation.
Owner:PIXIUM VISION SA

Image processing apparatus, control method thereof, and computer program

An image processing apparatus, which analyzes retina layers of an eye to be examined, comprising, means for extracting a feature amount, which represents an anatomical feature in the eye to be examined, from a projection image obtained from a tomogram of the retina layers and a fundus image of the eye to be examined, means for determining a type of the anatomical feature based on the feature amount, means for deciding layers to be detected from the retina layers according to the determined type of the anatomical feature, and detecting structures of the decided layers in the tomogram, and means for modifying the structure of the layer included in a region having the anatomical feature of the structures of the layers detected by the layer structure detection means.
Owner:CANON KK

OCT (Optical Coherence Tomography) image layer segmentation method based on neural network and constraint graph search algorithm

The invention relates to an OCT (Optical Coherence Tomography) image layer segmentation method based on a neural network and a constraint graph search algorithm, and is designed for accurately segmenting a retina layer and new vessels. The OCT image layer segmentation method based on the neural network and the constraint graph search algorithm comprises the following steps that: obtaining OCT image features to train a neural network classifier; obtaining a final SF1 through a multi-resolution map search algorithm SF1; extracting 24 features of an OCT image, and using the neural network classifier to find initial surfaces S1, S2,...S8; according to initial boundaries S2 to S8, using the constraint graph search algorithm to find accurate SF2 to SF8 in sequence; and segmenting the new vessels and hydrops between SF7 and SF8. The OCT image layer segmentation method based on the neural network and the constraint graph search algorithm has the advantages of being simple in operation and accurate in detection results. The existing problems of low identification rate, poor segmentation effect and the like of a lesion OCT image segmentation algorithm.
Owner:SUZHOU UNIV

Fundus image display apparatus, control method thereof and computer program

One aspect of embodiments of the present invention relates to an image processing apparatus which specifies one of boundary positions of retina layers in a fundus image showing a retina tomosynthesis, sets a distance transfer function for converting the distance from the specified boundary position to a parameter expressing opacity such that the peak position of the opacity is set to a predetermined position in the retina, sets a luminance transfer function for converting a luminance value of the fundus image to the parameter expressing opacity, and generates a translucent display image by calculating the opacity of respective positions of the tomosynthesis using the distance transfer function and the luminance transfer function, and by volume rendering.
Owner:CANON KK

Image processing apparatus and method

In a tomographic image photographing apparatus, a deformation of a volume image is corrected accurately even if an object to be inspected moves when the volume image is acquired. An image processing apparatus acquires a tomographic image of the object to be inspected from combined light beams of return light beams, which is obtained by irradiating the object to be inspected with a plurality of measuring light beams, and corresponding reference light beams. In the image processing apparatus, a photographing unit obtains a tomographic image of a fundus with the plurality of measuring light beams, and a detection unit detects a retina layer from the tomographic image. Based on the detected retina layer, a fundus shape is estimated. Based on the estimated fundus shape, a positional deviation between tomographic images is corrected.
Owner:CANON KK

Tomogram observation apparatus, processing method, and non-transitory computer-readable storage medium

A tomogram observation apparatus characterized by comprising: detection means for detecting a region in which an optic nerve extends from a retina layer of an eye to be examined to outside the eye to be examined; and generation means for generating a two-dimensional tomogram of a portion around an optic papilla of the eye to be examined, based on a position of the region.
Owner:CANON KK

Image processing apparatus, image processing method, and computer program

An image processing apparatus comprising, boundary extraction means for detecting boundaries of retina layers from a tomogram of an eye to be examined, exudate extraction means for extracting an exudate region from a fundus image of the eye to be examined, registration means for performing registration between the tomogram and the fundus image, and calculating a spatial correspondence between the tomogram and the fundus image, specifying means for specifying a region where an exudate exists in the tomogram using the boundaries of the retina layers, the exudate region, and the spatial correspondence, likelihood calculation means for calculating likelihoods of existence of the exudate in association with the specified region, and tomogram exudate extraction means for extracting an exudate region in the tomogram from the specified region using the likelihoods.
Owner:CANON KK

Retinal image layering method, device and equipment and readable storage medium

ActiveCN107578413AAvoid errorsAvoid Layering MistakesImage analysisPattern recognitionSelf adaptive
The invention discloses a retinal image layering method, device and equipment and a readable storage medium. The method comprises the following steps: carrying out straightening treatment to acquire aregion of interest of retinal layering operation; adaptively selecting the scale of superpixel over-segmentation according to thicknesses of various layers of a retina in the region of interest afterstraightening treatment is implemented so as to carry out initial over-segmentation on retinal images in the region of interest according to a preset clustering rule; and merging superpixel blocks obtained by initial over-segmentation by a preset merging rule so as to acquire a retinal layering result. By the provided method, device, equipment and computer readable storage medium, mistaken layering caused by weak contrast ratio of retina layers can be avoided effectively, and the accuracy of a retinal image layering result is improved.
Owner:JILIN UNIV

Model newborn human eye and face manikin

A model newborn human eye which includes a hemispherical-shaped, integrally molded top assembly comprising a visually transparent cornea portion surrounding a visually opaque sclera portion in combination with a hemispherical-shaped bottom assembly comprising a bowl-shaped substrate disposed therein. The model newborn human eye further comprises a retinal layer comprising a two dimensional image of retinal vasculature disposed on said substrate, where the model newborn human eye is dimensioned for diagnosing Retinopathy of Prematurity (“ROP”) in premature infants.
Owner:EYE CARE & CURE ASIA

Layer segmentation method and system for retina layer and effusion area based on deep learning

The invention discloses a layer segmentation method and system for a retina layer and an effusion area based on deep learning. The method comprises the following steps: acquiring a retina OCT data setof each node area in a medical system, dividing the data set into a pre-training data set and a test data set, and randomly translating data in the pre-training data set to obtain a training data set; carrying out forward propagation on the data in the training data set sent to the segmentation network in batches according to the constructed segmentation network and the corresponding loss function to obtain a segmentation prediction graph; according to a joint loss function formula, calculating a joint loss value between the segmentation prediction graph and a standard probability graph afterone-hot coding is carried out on the expert pixel-level marking image, carrying out back propagation on the joint loss value, and obtaining a segmentation network model through iterative training ofa preset period length; and testing the segmentation network model through the test data set to verify the reliability of the segmentation network model. According to the method and system, the generalization ability and the category segmentation accuracy of the segmentation network can be improved.
Owner:SUN YAT SEN UNIV

Optical coherence tomography retina image layering method

The invention provides an optical coherence tomography retina image layering method. The method comprises the steps of: firstly, carrying out de-noising preprocessing on an image; then setting a variable threshold for each A-scan image, carrying out segmentation layer by layer, and obtaining a preliminary layering result; and then carrying out continuity and integrity judgment on the preliminary layering result of each layer, correcting unsatisfactory segmentation points, and accurately and efficiently carrying out layering on the OCT retina image. The optical coherence tomography retina image layering method has the advantages that good layering processing can be carried out on the optical coherence tomography retina image which is high in noise and low in contrast and even has complex structures such as blood vessels, and the influences of a single threshold and high speckle noise on the retina layering effect are effectively reduced.
Owner:SHANGHAI INST OF OPTICS & FINE MECHANICS CHINESE ACAD OF SCI

Image processing apparatus and method for correcting deformation in a tomographic image

In a tomographic image photographing apparatus, a deformation of a volume image is corrected accurately even if an object to be inspected moves when the volume image is acquired. An image processing apparatus acquires a tomographic image of the object to be inspected from combined light beams of return light beams, which is obtained by irradiating the object to be inspected with a plurality of measuring light beams, and corresponding reference light beams. In the image processing apparatus, a photographing unit obtains a tomographic image of a fundus with the plurality of measuring light beams, and a detection unit detects a retina layer from the tomographic image. Based on the detected retina layer, a fundus shape is estimated. Based on the estimated fundus shape, a positional deviation between tomographic images is corrected.
Owner:CANON KK

A level set and deep learning combined retinal layer segmentation method and system

The invention discloses a level set and deep learning combined retina layer segmentation method and system, and the method comprises the steps: carrying out the preprocessing of an image collected byoptical coherence tomography equipment, enabling an active contour to evolve to a to-be-segmented boundary through a level set model through employing the priori information of the thickness of a retina layer, collecting normal retina OCT images and pathological retina OCT images, making classification labels, and constructing a training set and a test set; training a deep learning network by using the image data in the training set; processing the image data in the test set by using the trained deep learning network to obtain a retinal layer coarse classification result; and taking a retina layer coarse classification result as a level set function, evolving each level set function by adopting a gradient descent method, and obtaining a fine retina layer boundary.
Owner:SHANDONG NORMAL UNIV

Model human eye

InactiveUS20120231432A1Educational modelsCorneal surfaceA-scan ultrasound biometry
A model human eye suitable for practicing surgical procedures, comprising a hemispherical-shaped bottom assembly having a bowl-shaped substrate disposed therein, a retinal layer disposed on the bowl-shaped substrate, and a hemispherical-shaped top portion attached to the bottom portion, the top portion comprising a visually transparent cornea portion and a visually opaque sclera portion, wherein the cornea portion and the sclera portion are integrally molded, wherein the cornea portion comprises a posterior corneal surface, wherein a distance from the posterior corneal surface to the retinal layer is an axial length. The model human eye is particularly suited for practicing A-scan ultrasound biometry and optical coherence biometry.
Owner:OPTEGO VISION ASIA PTE LTD

Human eye retina imaging system and method capable of carrying out layered imaging

The invention discloses a human eye retina imaging system capable of carrying out layered imaging, comprising an illuminating system and an imaging system, wherein the imaging system comprises a wave-front sensor (316), a wave-front corrector (307), an imaging CCD (Charge Coupled Device) (314) and an oxyopter compensating mirror (303), wherein the wave-front sensor (316) is used for aberration measurement; the wave-front corrector (307) is used for aberration correction; the imaging CCD (314) is arranged on a stepping motor (313) and can move front and back along the direction of an optical axis for focusing; and the imaging CCD (314) can focus on different layers of a retina (301) to realize the layered imaging under the independent working or the joint working of the stepping motor (313), the wave-front corrector (307) and the oxyopter compensating mirror (303). The invention also discloses a human eye retina layered imaging method. The invention has simple structure and can effectively carry out layered observation on retinal layers composing the retina (301).
Owner:苏州六六视觉科技股份有限公司

OCT (Optical Coherence Tomography) image segmentation method based on random forest and composite active curve

The invention relates to an OCT (Optical Coherence Tomography) image segmentation method based on a random forest and a composite active curve, and is designed for accurately segmenting a retina layer and hydrops. The OCT image segmentation method based on the random forest and the composite active curve comprises the following steps that: obtaining OCT image features to train a random forest classifier, and obtaining a final SF1 through a composite active curve algorithm; extracting 24 features of the OCT image; and using the random forest classifier. The OCT image segmentation method based on the random forest and the composite active curve has the advantages of being simple in operation and accurate in detection results. The existing problems of low identification rate, poor segmentation effect and the like of a lesion OCT image segmentation algorithm are overcome.
Owner:SUZHOU UNIV

Robot remote fixed point control method for human eye subretinal injection

The invention relates to a robot remote fixed point control method for human eye subretinal injection, which comprises the following steps of: 1, selecting a needle inserting position, and setting a motion path of a mechanical arm; 2, obtaining an injection through an injector; 3, controlling the mechanical arm to move along a set movement path, and making the tail end of the needle tip move to a turning point along the movement path; 4, using the mechanical arm to drive the tail end of the needle tip to execute RCM movement at the turning point; 5, using the mechanical arm to drive the tail end of the needle tip to continue to move to the target position of the retina layer according to the movement path set in the step 2; and 6, injecting a certain amount of injection to the target position. According to the method, in a high-precision environment with resistance, the degree of freedom of motion of the mechanical arm can be guaranteed, a control mode of precisely completing closed-loop motion can be provided, the precision limitation caused when the mechanical arm is manually operated to complete a retina injection operation is overcome, the precision is improved, the difficulty of manual operation is reduced, and unnecessary injuries are avoided.
Owner:GUANGZHOU WEIMOU MEDICAL INSTR CO LTD

Retina interlayer gray level analysis method based on 3D-OCT

The invention discloses a retina interlayer gray level analysis method based on the 3D-OCT. The method includes the steps that firstly, an input 3D-OCT image is preprocessed; secondly, the multi-layer structure of the retina is segmented out through the image search technology; thirdly, detection is conducted through the texture classification method to find out the RAO area; fourthly, the gray levels of the retina layers are analyzed. According to the retina interlayer gray level analysis method based on the 3D-OCT, the gray levels of the retina layers in an RAO patient are analyzed in a quantitative mode, so that the qualitative judgment that the patient has the RAO disease is expressed in a quantitative mode, and quantitative indexes are provided, so that the severity degree of the RAO is independently and objectively judged. By proving the feasibility of the quantitative method, the foundation is laid for providing the objective basis of the illness state of the RAO patient for a doctor in future.
Owner:广州比格威医疗科技有限公司

Prediction method of choroidal neovascularization based on constitutive model and finite element method

The invention discloses a choroidal neovascularization growth protection method combining a constitutive model with a finite element. The method comprises the steps of image preprocessing; area division and partition, specifically including dividing an image into four areas consisting of a CNV area, an outer retina layer, an inner retina layer and a choroids layer; meshing, specifically including performing tetrahedral mesh generation on the four areas; modeling, specifically including modeling by using a hyperelastic biomechanical model and a reaction diffusion equation, and adding quality variation after choroidal neovascularization grows into an equation as a source item, thus causing a deformation gradient tensor to continuously change according to the growth of the new vessel; optimizing the model, computing the best accuracy rate, and performing parameter test; and fitting a parameter curve according to a parameter predicted at each time point, and predicting the growth parameter of the last time point to acquire a prediction result. According to the method provided by the invention, the biomechanical model can be built in a more flexible and personalized mode, the model assumes that organization is orthotropic, the good prediction results can be provided for non-linear large-deformation areas, and the accuracy is high.
Owner:SUZHOU BIGVISION MEDICAL TECH CO LTD

Apparatus for performing surgery inside the human retina using fluidic internal limiting membrane (ILM) separation (FILMS)

A method and apparatus for performing surgery inside the human retina using fluidic internal limiting membrane separation (FILMS) to remove the internal limiting retinal layer from the neural retinal layer at the macula. The method comprises inserting a hollow microcannula between the retinal internal limiting membrane and the neural retinal layer at or near the macula and injecting a sterile fluid, such as sodium hyaluronate, through said microcannula and thereby raising the macular internal limiting membrane retinal layer away from the neural retina such that it can then be removed by conventional means, while simultaneously smoothing the neural retina by localized pressure tamponad. The apparatus comprises a hollow microcannula having a proximal end a distal end and a distal tip. The distal end is shaped to conform tangentially to the surface of the retina. The distal tip is sharply beveled and adapted to discharge a fluid substance and to easily insert under the internal limiting membrane retinal layer and achieve occlusion of the lumen upon minimal insertion, and is sufficiently microscopic as to not substantially injure the neural retina when introduced under the ILM.
Owner:MORRIS ROBERT E

Spectacle lens, preparation method and glasses

The invention relates to the technical field of lenses and particularly relates to a spectacle lens, a preparation method and glasses. The spectacle lens comprises a prescription lens and at least two layers of micro-lens arrays arranged on the prescription lens, wherein the refractive powers of the at least two layers of micro-lens arrays are different. It can be understood that the refractive power of each layer of micro-lens array is different, the positions of the defocused virtual images generated by each layer are different, and the smaller the refractive power is, the closer the positions of the generated defocused virtual images to the retina is. When the micro-lenses in each layer of micro-lens array generate refractive power changing layer by layer, defocus imaging layers close to the retina or far away from the retina layer by layer can be generated, so eyes can gradually adapt to the defocus imaging layers, problems of visual discomfort, dizziness, eyestrain and the like caused by sudden increase of the defocus degree are avoided, the wearing comfort is better, and the effect of inhibiting or slowing down myopia development is better.
Owner:深圳市浓华生物电子科技有限公司

Method, device, equipment and readable storage medium for retinal image layering

ActiveCN107578413BAvoid errorsAvoid Layering MistakesImage analysisAdaptive selectionSelf adaptive
The invention discloses a retinal image layering method, device and equipment and a readable storage medium. The method comprises the following steps: carrying out straightening treatment to acquire aregion of interest of retinal layering operation; adaptively selecting the scale of superpixel over-segmentation according to thicknesses of various layers of a retina in the region of interest afterstraightening treatment is implemented so as to carry out initial over-segmentation on retinal images in the region of interest according to a preset clustering rule; and merging superpixel blocks obtained by initial over-segmentation by a preset merging rule so as to acquire a retinal layering result. By the provided method, device, equipment and computer readable storage medium, mistaken layering caused by weak contrast ratio of retina layers can be avoided effectively, and the accuracy of a retinal image layering result is improved.
Owner:JILIN UNIV

Layer Segmentation Method of Oct Image Based on Neural Network and Constrained Graph Search Algorithm

The invention relates to an OCT (Optical Coherence Tomography) image layer segmentation method based on a neural network and a constraint graph search algorithm, and is designed for accurately segmenting a retina layer and new vessels. The OCT image layer segmentation method based on the neural network and the constraint graph search algorithm comprises the following steps that: obtaining OCT image features to train a neural network classifier; obtaining a final SF1 through a multi-resolution map search algorithm SF1; extracting 24 features of an OCT image, and using the neural network classifier to find initial surfaces S1, S2,...S8; according to initial boundaries S2 to S8, using the constraint graph search algorithm to find accurate SF2 to SF8 in sequence; and segmenting the new vessels and hydrops between SF7 and SF8. The OCT image layer segmentation method based on the neural network and the constraint graph search algorithm has the advantages of being simple in operation and accurate in detection results. The existing problems of low identification rate, poor segmentation effect and the like of a lesion OCT image segmentation algorithm.
Owner:SUZHOU UNIV

3d-oct-based grayscale analysis method between retinal layers

The invention discloses a retina interlayer gray level analysis method based on the 3D-OCT. The method includes the steps that firstly, an input 3D-OCT image is preprocessed; secondly, the multi-layer structure of the retina is segmented out through the image search technology; thirdly, detection is conducted through the texture classification method to find out the RAO area; fourthly, the gray levels of the retina layers are analyzed. According to the retina interlayer gray level analysis method based on the 3D-OCT, the gray levels of the retina layers in an RAO patient are analyzed in a quantitative mode, so that the qualitative judgment that the patient has the RAO disease is expressed in a quantitative mode, and quantitative indexes are provided, so that the severity degree of the RAO is independently and objectively judged. By proving the feasibility of the quantitative method, the foundation is laid for providing the objective basis of the illness state of the RAO patient for a doctor in future.
Owner:广州比格威医疗科技有限公司
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