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Quantitative imaging device and method used for laser speckle blood flow velocity

A technology of blood flow velocity and laser speckle, which is applied in the field of optical imaging, can solve the problems of easy vibration of the stepping motor, complex and expensive system, and low time resolution, and achieve the effect of simple structure, good imaging quality, and high resolution

Active Publication Date: 2016-03-09
黄恺
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the time resolution of this imaging system is low, and the stepping motor is easy to shake, causing image shaking and making it less stable
[0004] Existing multiple-exposure contrast imaging methods, such as the US patent application US20120095354 "Laser Speckle Multiple Exposure Quantitative Imaging Method", this method uses multiple exposures to improve the quantitativeness of imaging, but the system is complex and expensive, slow speed problem

Method used

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  • Quantitative imaging device and method used for laser speckle blood flow velocity
  • Quantitative imaging device and method used for laser speckle blood flow velocity
  • Quantitative imaging device and method used for laser speckle blood flow velocity

Examples

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Embodiment 1

[0048] figure 1 As shown, the structure of this example is as follows:

[0049] A quantitative imaging device for laser speckle blood flow velocity, wherein: including three lasers 1, ground glass 2, two CMOS cameras 4, and a computer 5, the ground glass 2 is provided under the laser 1; Two CMOS cameras 4 are connected with computer 5 respectively, and the below of described two CMOS cameras 4 is provided with 50:50 beam splitter 6.

[0050] Moreover, a light emitting diode 8 is provided below the 50:50 beam splitter 6 in this example; a filter 7 is provided between the 50:50 beam splitter 6 and the light emitting diode 8 .

[0051] In this example, a semiconductor laser with a wavelength of 785 nanometers is used as the light source, the pixel of the CMOS camera is 640×480, the exposure time is 0.6ms, and the readout frequency is 750 frames per second.

[0052] Using the device of this example, the method of realizing quantitative imaging adopts the following steps:

[005...

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Abstract

The invention discloses a quantitative imaging device and method used for laser speckle blood flow velocity. The device comprises a laser device, frosted glass, image acquisition equipment and a computer, wherein the frosted glass is arranged below the laser device; the image acquisition equipment is connected with the computer; and a light splitter is arranged below the image acquisition equipment. The imaging device and method, provided by the invention, have the advantages of high accuracy in time domain and space domain at the same time, and good quantitative feature, and can achieve measurement to local laser Doppler signals; and the imaging device is high in resolution, excellent in imaging quality, and strong in image stability.

Description

technical field [0001] The invention relates to an optical imaging technology, in particular to a blood flow imaging system and method based on the laser speckle principle and the Doppler principle. Background technique [0002] At present, laser speckle blood flow imaging technology is becoming more and more mature, which has the advantages of optical imaging without ionizing radiation and non-contact measurement. Specifically, this technology uses biological tissue backward speckle to obtain blood flow velocity information, and obtains a full-field two-dimensional high-resolution blood flow distribution image through imaging. Its advantages are: no need to combine mechanical scanning; no injection contrast It can realize long-term continuous blood flow monitoring; combined with CCD camera and other image acquisition equipment and high-performance parallel computing equipment, this technology can achieve micron-level spatial resolution and millisecond-level temporal resolut...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/026
CPCA61B5/0261A61B5/72
Inventor 蒋勇刚黄恺
Owner 黄恺
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