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Method for preparing pharmaceutical composition for treating community-acquired pneumonia

A technology for acquired pneumonia and a composition is applied in the field of preparing a pharmaceutical composition for treating community-acquired pneumonia, which can solve the problems of long course of treatment, insignificant effect, and single applicability, and achieves short course of treatment, wide applicability, and dosage of medication. less effect

Inactive Publication Date: 2016-03-30
QINGDAO HUAZHICAO PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] There are many invention patents for the treatment of community-acquired pneumonia published at present, for example: Chinese invention patent application: 201410822536.1 discloses the use of a pharmaceutical composition in the preparation of medicines for the treatment of community-acquired pneumonia, the pharmaceutical composition includes Radix Pseudostellariae, Radix Astragali , Ophiopogon japonicus, Polygonatum odoratum, Palm ginseng, Rehmannia glutinosa, Trichosanthum pollen, Scutellaria baicalensis, Hedyotis diffusa, and licorice, but the existing pharmaceutical compositions have relatively single applicability, long course of treatment, and no obvious effect

Method used

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  • Method for preparing pharmaceutical composition for treating community-acquired pneumonia
  • Method for preparing pharmaceutical composition for treating community-acquired pneumonia
  • Method for preparing pharmaceutical composition for treating community-acquired pneumonia

Examples

Experimental program
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Effect test

Embodiment 1

[0039] The pharmaceutical composition of Example 1 of the present invention includes the following preparation raw materials in parts by weight: 10 parts of mulberry leaves, 9 parts of fresh rehmannia glutinosa, 8 parts of cotyledon leaves, 8 parts of Chuan Fritillaria, 6 parts of radish seeds, 3 parts of Radix Ginseng, 3 parts of Shicao, 3 parts of Ophiopogon japonicus, 3 parts of Xuelikai, 3 parts of Dendrobium, 2 parts of ginseng and 1 part of licorice.

[0040] Preparation:

[0041] S1: Take mulberry leaves, wash away impurities, dry with hot air at 50°C for 5 hours, control the moisture content to 5%, pulverize, pass through a 50-mesh sieve to obtain coarse powder, and suck the coarse powder into an airflow ultrafine pulverizer for ultrafine pulverization, The crushing pressure is 0.5MPa, the feed rate is 30mg / s, and after drying, carry out superfine pulverization respectively, and pass through a 800 mesh sieve to obtain mulberry leaf superfine powder, which is set aside;...

Embodiment 2

[0046] The pharmaceutical composition of Example 2 of the present invention includes the following preparation raw materials in parts by weight: 15 parts of mulberry leaves, 12 parts of fresh rehmannia glutinosa, 12 parts of cotyledon leaves, 10 parts of Chuan Fritillaria, 9 parts of radish seeds, 6 parts of Radix Ginseng, 6 parts of Shicao, 5 parts of Ophiopogon japonicus, 5 parts of Xuelikai, 4 parts of Dendrobium, 4 parts of ginseng and 5 parts of licorice.

[0047] The preparation method is as in Example 1.

Embodiment 3

[0049] The pharmaceutical composition of Example 3 of the present invention includes the following preparation raw materials in parts by weight: 20 parts of mulberry leaves, 15 parts of fresh rehmannia glutinosa, 15 parts of cotyledon leaves, 12 parts of Chuan Fritillaria, 12 parts of radish seeds, 10 parts of Radix Ginseng, orchid 10 parts of Shicao, 8 parts of Ophiopogon japonicus, 8 parts of Xuelikai, 6 parts of Dendrobium, 6 parts of ginseng and 10 parts of licorice.

[0050] The preparation method is as in Example 1.

[0051] Pharmacodynamic study of the pharmaceutical composition of the present invention:

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Abstract

The invention belongs to the technical field of traditional Chinese medicines, and relates to a method for preparing a pharmaceutical composition for treating community-acquired pneumonia. The method comprises the following steps: performing superfine grinding on mulberry leaves for later use; decocting fresh rehmannia, thorny elaeagnus leaves, bulbus fritillariae cirrhosae, semen raphani, adenophora stricta, herb of tibet lancea, radix ophiopogonis, henry clematis root, dendrobe, ginseng and licorice root to obtain filtrate, storing filter residues, concentrating the filtrate to obtain an extract for later use; performing alcohol extraction and concentration on the filter residues to obtain an extract for later use; and uniformly mixing the two extracts, drying at reduced pressure, grinding, screening, uniformly mixing with the mulberry leaf superfine powder, adding auxiliaries, and preparing the clinically required finished product preparation by utilizing a modern universal traditional Chinese medicine preparation technology. The preparation process is simple, and is suitable for industrial production. The pharmaceutical composition has the advantages of strong pertinence, remarkable curative effect and high cure rate when being used for treating community-acquired pneumonia.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and relates to a method for preparing a medicinal composition for treating community-acquired pneumonia. Background technique [0002] Community-acquired pneumonia refers to infectious lung parenchyma (including alveolar wall, that is, pulmonary interstitium in a broad sense) inflammation that is induced outside the hospital, including pneumonia with a clear incubation period of pathogen infection that occurs during the incubation period after admission to the hospital. CAP is one of the common infectious diseases that threaten human health. The composition and drug resistance characteristics of its pathogens are significantly different in different countries and regions, and they are constantly changing with the passage of time. [0003] In recent years, due to the aging of the social population, the increase of immune compromised hosts, the change of pathogens and the incre...

Claims

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Application Information

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IPC IPC(8): A61K36/8984A61P11/00
CPCA61K36/605A61K36/185A61K36/23A61K36/258A61K36/31A61K36/34A61K36/342A61K36/484A61K36/716A61K36/80A61K36/804A61K36/8966A61K36/8968A61K36/8984A61K2236/15A61K2236/331A61K2236/333A61K2236/39
Inventor 刘学键
Owner QINGDAO HUAZHICAO PHARMA CO LTD