A kind of viscoelastic nanoemulsion and preparation method thereof

Abstract

The invention discloses a viscoelastic nanoemulsion, comprising 100 parts by weight, 10-40 parts of oil phase, 5-10 parts of emulsifier, 7×10-4-3.5×10-1 parts of bioglue, and the balance of water; The emulsifier is a mixture of lipophilic emulsifier and hydrophilic emulsifier; the lipophilic emulsifier is a mixture of Span20 and TX4; the hydrophilic emulsifier is a mixture of Brij 35 and Tween 20. The invention also discloses a preparation method thereof, the steps are as follows: at 20-25°C, add the emulsifier into the oil phase and stir evenly to obtain a nano-emulsion mixture; dissolve biogel in water to obtain a water phase solution; The phase solution is added dropwise to the nanoemulsion mixture at a uniform speed and stirred at the same time to form a nanoemulsion. The present invention utilizes emulsifier compounding and bio-glue embedding to form viscoelastic adsorption layers on both sides of the oil-water interface on the nanoparticle surface, improving the viscoelasticity and stability of the oil-water interface, and the particle size distribution is narrow and stable.

Description

technical field [0001] The invention belongs to the technical field of nanoemulsion preparation, in particular to a viscoelastic nanoemulsion and a preparation method thereof. Background technique [0002] Emulsion refers to a dispersion system in which the dispersed phase is dispersed in the continuous phase composed of another phase (non-solvent) in the form of small droplets. It is a thermodynamically unstable polydisperse system, and the diameter of the dispersed phase is generally between 0.1 and 10 μm. Emulsions with diameters between 50 and 500 nm are called nanoemulsions. As a special type of emulsion, compared with ordinary emulsion, nanoemulsion has smaller droplet size, uniform dispersion, and certain dynamic stability. It can avoid obvious flocculation and coalescence within several months or even half a year. More excellent properties and application prospects. Therefore, nanoemulsion technology has penetrated into the fields of petrochemical industry, daily c...

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Problems solved by technology

Whether it is partially hydrolyzed polyacrylamide or hydrophobically modified polyacrylamide, it will contain a certain amount of acrylamide monomer, and the molecular chain of polyacrylamide will be sheared and broken under the action of shear force to obtain small molecule acrylamide. Acrylamide aggregates, and acrylamide is a substance with potential neurotoxicity, genotoxicity and carcinogenicity. Therefore, there are certain safety hazards in the application of nanoemulsions obtained by this method, and its application range will be greatly restricted. limit

The patent application number 201410514585.9 discloses a salt-free anion / cation surfactant-stabilized viscoelastic emulsion and its preparation method. Although it has a certain viscoelasticity, it can be deformed when it is sheared during the flow process, but this The water-in-oil emulsion prepared by this method has a particle size of micron size. Compared with the nano-sized particle size emulsion, the particle size distribution is wider and the stability is relatively poor.

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