Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Natural product anti-inflammation medicine composition and use thereof

An anti-inflammatory drug and composition technology, applied in the field of medicine, can solve problems such as adverse reactions, and achieve the effects of clear pharmacological effects, reduced foot swelling, and reduced release

Inactive Publication Date: 2016-05-25
INST OF BIOMEDICAL ENG CHINESE ACAD OF MEDICAL SCI
View PDF0 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Non-steroidal drugs are currently recommended first-line drugs for the treatment of inflammatory diseases, including aspirin, acetaminophen, diclofenac, indomethacin, ibuprofen, etc., but these drugs have corresponding side effects, such as adverse gastrointestinal tract reaction etc.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Natural product anti-inflammation medicine composition and use thereof
  • Natural product anti-inflammation medicine composition and use thereof
  • Natural product anti-inflammation medicine composition and use thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Embodiment 1 physical mixing

[0025] Take 0.7g ligustrazine, 0.18g resveratrol, 1.75g ​​curcumin, mix physically, and dissolve 0.5% sodium carboxymethylcellulose for animal experiments or clinical oral administration.

Embodiment 2

[0026] Embodiment 2 physical mixing

[0027] Take 3.0g ligustrazine, 0.83g resveratrol, 11.25g curcumin, mix physically, and dissolve 0.5% sodium carboxymethylcellulose for animal experiments or clinical oral administration.

Embodiment 3

[0028] Embodiment 3 physical mixing

[0029] Take 1.85g ligustrazine, 0.93g resveratrol, 9.25g curcumin, mix physically, and dissolve 0.5% sodium carboxymethylcellulose for animal experiments or clinical oral administration.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a natural product anti-inflammation medicine composition and a use thereof. Every dosage unit includes 0.7-3.0g of ligustrazine, 0.1-1.1g of resveratrol and 1.7-11.7g of curcumin, and the dosage unit is the total amount of the above medicine precision used every day. The medicine composition adopting ligustrazine, resveratrol and curcumin as active components is prepared through directly physically mixing 0.7-3.0g of ligustrazine, 0.1-1.1g of resveratrol and 1.7-11.7g of curcumin, or a pharmaceutically acceptable carrier is added to make the total weight of ligustrazine, resveratrol and curcumin account for 0.5-40% of the total weight of the medicine composition in order to prepare any clinically acceptable oral dosage form. The invention also provides a use of the medicine composition adopting the ligustrazine, resveratrol and curcumin as active components in the preparation of anti-inflammation medicines. The medicine composition adopting the ligustrazine, resveratrol and curcumin as active components has the characteristics of simple preparation method, convenient quality control, high efficiency and low toxicity, and can be used to treat pneumonia, hepatitis, nephritis, arthritis, pyohemia, ulcerative colitis, asthma, atherosclerosis and other clinic common inflammation diseases.

Description

technical field [0001] The present invention belongs to the technical field of medicine, and in particular relates to a natural product anti-inflammatory pharmaceutical composition and its use, in particular to the preparation of three natural products of ligustrazine, resveratrol and curcumin into a pharmaceutical composition, and the preparation of the pharmaceutical composition in Application in the preparation of anti-inflammatory drugs. Background technique [0002] Inflammation can usually be divided into two categories according to the course of the disease: acute inflammation (acute inflammation) and chronic inflammation (chronic inflammation). Acute inflammation has a sudden onset and a short duration of only a few days to a month. It is characterized by exudative lesions, and the infiltration of inflammatory cells is mainly granulocytes. Chronic inflammation lasts for a long time, constant months to several years, mainly hyperplastic lesions, and its inflammatory ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/4965A61P29/00A61P11/00A61P1/16A61P13/12A61P19/02A61P1/04A61P11/06A61P9/10A61K31/05A61K31/12
Inventor 刘天军陈龙刘娟洪阁
Owner INST OF BIOMEDICAL ENG CHINESE ACAD OF MEDICAL SCI
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com