Blood identification method based on infrared Raman super-continuum diffuse comprehensive spectrum

A supercontinuum and diffuse comprehensive technology, applied in the field of non-contact identification of blood samples in sealed test tubes, can solve problems such as affecting the optical properties of blood, and achieve the effects of improving identification accuracy, improving signal-to-noise ratio, and eliminating fluorescence interference.

Active Publication Date: 2016-06-01
SHANGHAI INST OF TECHNICAL PHYSICS - CHINESE ACAD OF SCI
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Problems solved by technology

These interference factors will seriously affect the optical properties of blood, making common optical and spectral methods powerless in the identification of blood in sealed test tubes

Method used

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  • Blood identification method based on infrared Raman super-continuum diffuse comprehensive spectrum

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Embodiment Construction

[0036] The hardware system structure of the sealed blood discriminator based on infrared Raman combined with supercontinuum integrated laser spectroscopy is as follows: figure 1 As shown, the hardware system mainly consists of a power supply module 1, a visible spectrum spectrometer 2, an infrared spectrum spectrometer 3, two-input and two-out optical fibers 5, a main control and data analysis system 7, an integrating sphere 35, a test tube manipulator 10, and a connecting rod 11 , guide rail 12, manipulator motion controller 13, sample outdoor cover 18, bottom plate 22, bracket 29, light source outdoor cover 30, optical fiber collimation connector 31, laser pigtail 32, supercontinuum laser 34, objective lens bracket 39, display Micro-objective lens 40, objective lens coupler 41, fiber collimator 42, Y-shaped coaxial optical fiber 43, fiber coupler 44, and infrared narrow-linewidth laser 49 are composed.

[0037] Wherein, the integrating sphere 35 is composed of two hemisphere...

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Abstract

The invention discloses a blood identification method based on an infrared Raman super-continuum diffuse comprehensive spectrum. The blood identification method comprises the following six steps: starting an instrument, and feeding a sample for super-continuum spectrum test; performing super-continuum spectrum laser diffuse comprehensive spectrum test; feeding a sample for Raman spectrum test; performing infrared laser Raman spectrum test; analyzing and fusing data; identifying and distinguishing blood. The blood identification method has the beneficial effects that a two-in and two-out optical fiber complex spectrometer is connected by using a Y-shaped optical fiber so as to form the hardware, an infrared Raman spectrum and a super-continuum diffuse comprehensive laser spectrum are in weighted stack so as to form the software, and thus spectrum data information fusion can be achieved. Due to the hardware structure and robustness of software analysis, the blood identification method can be applied to automatic identification of whole blood, plasma and serum.

Description

technical field [0001] The invention relates to a human and animal blood classification instrument and method, in particular to a method for non-contact identification of blood samples in sealed test tubes based on infrared Raman combined with supercontinuum integrated laser spectroscopy. Background technique [0002] At present, my country adopts a credit system for the import and export of blood and other various biological materials, but the authenticity of various biological materials cannot be directly tested for various reasons. Especially when it comes to special materials such as blood samples, open contact sampling conditions are often not allowed. On the one hand, the blood sample may be contaminated by the testing operation; on the other hand, the pathogenic factors that the blood sample itself may carry will cause occupational exposure to the testing personnel. In view of the above reasons, it is urgent to develop a non-contact rapid detection method for blood s...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/65G01N21/3577
CPCG01N21/3577G01N21/65
Inventor 万雄刘鹏希章婷婷陈学岗张志敏张华明
Owner SHANGHAI INST OF TECHNICAL PHYSICS - CHINESE ACAD OF SCI
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