Efficient synthesis process of glycine

Abstract

The present invention discloses an efficient synthesis process of glycine, and provides a glycine synthesis process with characteristics of short time consuming, simple operation and high synthesis yield. The synthesis steps comprise that 700 ml of a circulating mother liquor is added to a beaker, 6-11 g of methenamine is added to the mother liquor in a supplemented manner, 16-30 g of a co-catalyst Cat is added, 270-280 g of ammonium bicarbonate is completely added to the beaker, 334-340 g of ammonium-monochloracetat is poured into the beaker in one time, the temperature of the reaction system is increased to 30-40 DEG C by using water bath, CO2 escapes from the solution in the reaction, the reaction temperature is increased to 40-50 DEG C within 1 h, the reaction is significantly accelerated, the reaction releases heat to make the temperature of the system automatically rise, the temperature is controlled through water bath, the temperature of the system is maintained at 50-55 DEG C for 2 h, the temperature is increased to 60-62 DEG C and is maintained for 1 h so as to complete the reaction, and natural cooling is performed to achieve a room temperature, wherein the total reaction time is about 4 h.

Description

technical field [0001] The invention belongs to the technical field of chemical synthesis, and in particular relates to a high-efficiency synthesis process of glycine. Background technique [0002] Glycine is a non-essential amino acid. Glycine has the simplest structure in the amino acid series. It has both acidic and basic functional groups in the molecule. It is a strong electrolyte in aqueous solution and has a large solubility in strong polar solvents. It is basically insoluble in non-polar Solvent, and has a higher boiling point and melting point, through the adjustment of the acidity and alkalinity of the aqueous solution, glycine can present different molecular forms. Glycine has a unique sweet taste, which can ease the acid and alkali taste, cover the bitter taste of saccharin added in food and enhance the sweet taste. In the current glycine synthesis process method, the technical process is not easy to implement, the resulting glycine product has low purity, low...

AI Technical Summary

Problems solved by technology

In the current glycine synthesis process method, the technical process is not easy to implement, the resulting glycine product has low purity, the single-pass conversion rate of reactants is low, the production process is complicated, the production efficiency is low and the cost is high, and it is not suitable for large-scale production.