39 results about "Glycine product" patented technology

This invention generally relates to processes for recovering solubilized noble metals from aqueous process streams, in particular, aqueous process streams generated in the preparation of an N-(phosphonomethyl)glycine product, for example, by noble metal-catalyzed oxidation of an N-(phosphonomethyl)iminodiacetic acid substrate. The process includes contacting the aqueous process stream with a noble metal adsorption media such as an ion exchange resin to remove solubilized noble metal from the process stream.

A treatment for de-oxygenating a noble metal on carbon catalyst used in liquid phase oxidation reactions which includes exposing the catalyst to a non-oxidizing environment. The de-oxygenation treatment improves catalyst performance and is particularly suited for noble metal on carbon catalysts used to catalyze the oxidative cleavage of a carboxymethyl substituent from an N-(phosphonomethyl)iminodiacetic acid substrate in an aqueous reaction mixture using an oxygen-containing gas to produce an N-(phosphonomethyl)glycine product. In one embodiment, the catalyst is exposed to a non-oxidizing environment by introducing a non-oxidizing gas and/or reducing gas into a slurry comprising the catalyst in contact with a liquid medium.

The invention provides a method for separating mixed crystals of glycine and ammonium chloride. According to the method, the mixed crystals of glycine and ammonium chloride are separated by two-step crystallization respectively by using a glycol solvent and a water solution as media, so as to obtain a glycine product with high purity and a by-product ammonium chloride. According to the method, based on good use of the difference between glycine and ammonium chloride in solubility in the glycol solvent and the water solution, glycine and ammonium chloride are separated under the mild operation condition; the used glycol solvent is small in volatility, free of damage in an operation process, and easy to recover, the problems of methyl alcohol volatilization, high energy consumption in evaporation recovery and the like in the methyl alcohol separation process are overcome, and the separation reagent in the whole technical process is recycled, so that the production cost is saved and non-pollution emission is achieved.

The invention discloses a novel glycine synthesis process, and belongs to the technical field of glycine production. Chloroacetic acid and ammonia gas serve as raw materials, aminolysis reaction is performed in water solution of methenamine serving as a catalyst, first cooling crystallization is performed after reaction to obtain mixed crystals and mother solution, the mixed crystals are dissolvedby water and then subjected to second cooling crystallization, obtained initial products are washed by low-temperature water and then centrifugally separated and dried to obtain a glycine product, the mother solution is separated by electrodialysis to obtain glycine and methenamine mixed solution and ammonium chloride water solution; conveying the glycine and methenamine mixed solution to a preceding procedure for mechanical application; evaporating, concentrating and crystallizing the ammonium chloride water solution to obtain ammonium chloride. The novel glycine synthesis process solves theproblems that production cost is increased by alcohol-water mixture, mother solution distillation needs a large quantity of energy consumption, and by-product ammonium chloride product is low in theprior art.

The invention discloses an Escherichia coli recombinant bacterium for efficiently utilizing fatty acids to synthesize glycine and a construction method and application thereof. Escherichia coli recombinant bacterium contains one or more of that following genetic modification: (1) enhancement of fatty acid uptake pathway and fatty acid beta oxidation pathway; (2) glyoxylate cycle-related gene targets were modified to enhance glyoxylate synthesis; (3) introduction/enhancement of glutamate glyoxylate transaminase gene expression. The engineering strain of the invention has the ability to convertwhole cells of fatty acid substrates of different lengths into glycine, which can be stearic acid (C18), palmitic acid (C16), tetradecanoic acid (C14), lauric acid (C12), decanoic acid (C10), octanoicacid (C8) or caproic acid (C6). The ability of the engineered strain to synthesize glycine from fatty acids makes it useful for the industrial production of glycine products.

The invention provides a method for continuously preparing glycine from hydroxyacetonitrile by a microchannel reactor. The method comprises the following steps: preheating and mixing hydroxyacetonitrile, a carbon source and an ammonia source which serve as raw materials, sequentially performing hydantoin synthesis and hydantoin hydrolysis reaction in the microchannel reactor to obtain a glycine aqueous solution, and performing steam stripping, evaporation and concentration, crystallization, separation, decoloration and drying to obtain the glycine product. Compared with an existing method, themethod realizes continuous preparation of the glycine by taking the hydroxyacetonitrile as the raw material, and has the advantages of short reaction time, few byproducts, high glycine yield and lowpreparation cost.

The invention relates to a method for producing glycine and co-producing ammonium chloride by using an organic solvent, wherein the organic solvent comprises: ethylene glycol, propylene glycol, dimethylacetamide (DMAC), and methanol and ethanol capable of being blended in the previous solvents. According to the present invention, a reaction organic solvent and a catalyst urotropine are added to areactor for producing glycine, chloroacetic acid is added, ammonia is introduced to synthesize glycine, and cooling, filtration, washing and drying are sequentially performed to obtain the glycine product; and chloroacetic acid or ammonium chloroacetate is added to the organic solvent, ammonium chloride is precipitated and crystallized, and washing and drying are performed to obtain the ammonium chloride product, wherein the organic solvent is recycled.

The invention provides an aftertreatment technology of hydantion serialization preparation of glycine. The technology comprises the steps that a steam machine re-compression technology is adopted forevaporating and concentrating a glycine aqueous solution to obtain a concentration solution, and the glycine aqueous solution is obtained in the mode that glycollic nitrile, an ammonia source and a carbon source are subjected to synthesis and hydrolysis reactions in sequence; the concentration solution is subjected to crystallization and purification to obtain glycine crystals and a glycine mothersolution; the glycine crystals are subjected to recrystallization and purification to obtain a glycine product and a recrystallization mother solution; the crystallization mother solution and the recrystallization mother solution are circulated to a hydrolysis reaction kettle, and the crystallization mother solution, the recrystallization mother solution and a synthetic reaction solution are hydrolyzed. According to the aftertreatment technology, in the evaporation and concentration process, live steam does not need to be consumed, the crystallization mother solution and the recrystallizationmother solution are circulated to the hydrolysis reaction kettle for continuous hydrolysis, the loss of the glycine can be reduced, and the quality of the glycine can be improved.

The invention relates to a method for producing glycine by using an organic solvent, and provides a clean production technology of the glycine. According to the method, the glycine is prepared by using a glycols solvent (such as ethylene glycol, propylene glycol or butanediol), or a glycol derivative solvent (such as ethylene glycol monomethyl ether, ethylene glycol monoethyl ether or ethylene glycol monobutyl ether) and a methyl alcohol (or ethyl alcohol) organic solvent. The method comprises the steps of adding the organic solvent and a catalyst-urotropine into a reactor used for producing the glycine, then adding chloroacetic acid into the reactor, slowly replenishing the reactor with ammonia, and carrying out a reaction for synthesizing the glycine; after the reaction is finished, filtering out glycine crystals at the temperature of 50-75 DEG C, washing the glycine crystals with methyl alcohol (or ethyl alcohol), filtering, and drying to obtain a glycine product; cooling filtrate by freezing, then filtering to obtain mixed crystal solid of ammonium chloride and a small amount of glycine, and washing to obtain an ammonium chloride product, wherein the reaction solvents can be reused.

The invention discloses a clean process for continuously synthesizing glycine. The process comprises the following steps: preheating a carbon dioxide ammonia water solution prepared from an ammonia source, a carbon source and water, mixing the preheated solution with glycolonitrile, performing continuous synthesis, reduced pressure flash evaporation, continuous hydrolysis, gas stripping, concentrating, cooling and crystallizing, centrifuging for the first time, carrying out hot-melting recrystallization, centrifuging for the second time and drying to obtain a glycine product. Part of carbon dioxide generated by hydrolysis in the hydrolysis reaction process is continuously separated; and a carbon dioxide and ammonia recovery system sequentially absorbs the gas phase obtained by gas stripping, hydrolysis separation and reduced pressure flash separation to obtain a carbon dioxide ammonia water solution, and the carbon dioxide ammonia water solution is recycled to the reaction system. According to the process, the yield of glycine is increased by restraining iminodiacetonitrile side reaction; through timely release of each gas phase in the system and reasonable arrangement of the recovery sequence, the difficulty of recycling carbon dioxide and ammonia in the system is reduced, the loss of carbon dioxide and ammonia is reduced, the hydrolysis one-way conversion rate is improved, the hydrolysis time is greatly shortened, and the process is an environment-friendly and clean process for producing glycine.

The invention discloses a high efficiency production method of glycine. The high efficiency production method comprises following steps: solvent methanol or ethanol, and catalyst urotropine or paraformaldehyde are introduced into a reactor, Ammonium-monochloracetat is added, the temperature is increased to 60 to 70 DEG C, N,N-Diisopropylethylamine or N,N-Diethylbenzylamine or N, N-di-n-propyl benzylamine or N, N-di-n-butyl benzylamine are added dropwise in 2h, thermal insulation reaction is carried out at 65 to 75 DEG C for 2.5h, the temperature is reduced to 40 to 50 DEG C for precipitation of glycine crystal, or the temperature is reduced to 10 to 25 DEG C for precipitation of a mixture of glycine crystal and an ammonium salt; and then filtering, washing, and drying are carried out successively so as to obtain a glycine product, wherein a washing liquid is adopted for recycling of N,N-Diisopropylethylamine or N,N-Diethylbenzylamine or N, N-di-n-propyl benzylamine or N, N-di-n-butyl benzylamine. The glycine yield is increased by 10% of that in the prior art; energy consumption is reduced; catalyst recycling is realized; recycling of N,N-Diisopropylethylamine or N,N-Diethylbenzylamine or N, N-di-n-propyl benzylamine or N, N-di-n-butyl benzylamine is realized; and combined production of ammonium chloride is realized.

The invention relates to a device and a process for washing a glycine crude product through an alcohol phase method. A glycine centrifuge is connected with a diluted methanol washing tank which is connected with a glycine extraction kettle through a diluted methanol pump, the glycine extraction kettle is connected with an extracted glycine centrifuge which is connected with a methanol rectifying tower through an extract transfer pump, and the methanol rectifying system is connected to a red ammonium concentration system. Alcohol and chloroacetic acid are taken as a solvent and an initial raw material respectively in the process, a glycine product meeting glyphosate synthesis requirements and reaching national standards (main content being greater than or equal to 98.5% and chlorine root being less than or equal to 0.4%) is obtained by treating the glycine crude product (glycine main content being 93-96%, chlorine root being 2-4% and other impurities being lower than 1%) produced by newprocesses like a mixed solvent or organic amine or novel halogen formula reagent method through a systematic industrial washing process, and glycine synthesis yield is unaffected; wastewater is completely recycled into a system, so that clean production is realized.

The invention relates to a production method for feed-grade and food-grade glycine and a device for implementing the method. The method comprises the following steps: with an aqueous hydroxyacetonitrile solution and an aqueous ammonium carbonate solution as raw materials, sequentially conducting reacting at 100-135 DEG C and 150-160 DEG C in the presence of a zirconium raw material, and controlling the liquid level of the reactions to be 75% or more; in the presence of the zirconium raw material, concentrating obtained reaction feed liquid under heating, removing ammonia and carbon dioxide, and then performing decoloration; and then in the presence of the zirconium raw material, subjecting the obtained decoloration solution to vacuum concentration and crystallization so as to obtain feed-grade and food-grade glycine products, wherein the yield of glycine is 97% or above in terms of glycolonitrile. The production method has the advantages that almost no three wastes are generated, the method is clean and environment-friendly, no organic solvent is needed, repeated recrystallization is not needed, the yield of feed-grade and food-grade glycine is high, production cost is low, an automation degree is high, and the like.

The invention discloses a glycine production technology. The glycine production technology comprises steps as follows: a mixed solution is prepared from a crude glycine product which is produced with a chloroacetic acid aminolysis method and contains glycine and inorganic salt through dissolving with deionized water, the mixed solution is subjected to ceramic membrane separation, continuous chromatographic separation, concentration, crystallization, centrifugation and crystal drying, and glycine crystals and ammonium chloride crystals are obtained. With the adoption of the technical scheme of the glycine production technology, glycine production is performed by adopting ceramic membrane separation and continuous chromatographic separation systems, and the glycine production technology has the beneficial effects that the target products, namely, glycine and ammonium chloride, are high in product quality, high in yield and low in energy consumption.

The invention relates to a preparation method of glycine, which belongs to the technical field of chemical production and comprises the following five steps: preparing an ammonium chloroacetate solution, preparing a product glycine solution, preparing a glycine finished product, recovering to obtain an organic amine hydrochloride crystal solid and a filtrate containing urotropine, recovering an organic amine solution and preparing an ammonium chloride solid. The preparation method disclosed by the invention is simple and environment-friendly, the prepared glycine product is high in purity, and meanwhile, an industrial-grade ammonia chloride product can be obtained through co-production; the organic amine, the methanol and the catalyst urotropine used in the preparation process can be recycled, so that the production cost is saved, and the purpose of zero emission is achieved.

The invention provides a clean production process of glycine, which can co-produce ammonium chloride product while producing glycine; and co-produce triethylamine hydrochloride product while producing glycine. Add solvent methanol and catalyst to the reactor of glycine ammonolysis reaction, add solid ammonium chloroacetate, start adding triethylamine when the temperature rises to 65°C, complete the addition of triethylamine within one and a half hours, keep warm for two and a half hours to pH The value is 7.5. Respectively cool down and freeze to separate glycine and triethylamine hydrochloride. The triethylamine in the triethylamine hydrochloride is recovered by the method of passing through ammonia, and the ammonium chloride product is co-produced at the same time.

The invention relates to a process and a device for producing glycine by an alcohol phase method. The main process comprises the following steps: taking methanol as a solvent, urotropin as a catalystand liquid or solid chloroacetic acid as an initial raw material, firstly introducing ammonia to produce a mixed crystal of glycine and ammonium chloride, centrifuging to obtain a mixed crystal, repeatedly applying the filtrate to synthesis of the mixed crystal, dissolving the mixed crystal by using pure water, extracting a glycine product by using methanol; enabling filtrate after glycine is centrifuged out to enter a rectifying tower to recover methanol, enabling rectified residual liquid to enter a film evaporator, concentrating the rectified residual liquid until water is completely evaporated to directly obtain an ammonium chloride byproduct, and repeatedly using water evaporated from the film evaporator to dissolve mixed crystals. The process mainly uses a glycine synthesis kettle, aglycine extraction kettle, a mixed crystal filtrate elevated tank, a centrifugal machine, a mixed crystal filtrate receiving tank, a chloroacetic acid dissolving kettle, a methanol rectifying tower,a film evaporator, and the like. According to the method, the unit consumption levels of urotropin, liquid ammonia, and steam can be greatly reduced, the production cost is further reduced, and no wastewater is generated.

The invention discloses a method for preparing glycine by using an environment-friendly novel catalyst in a water phase. The novel catalyst is mainly a pyridine base compound, and comprises 4-dimethylaminopyridine (DMAP), 2,4-dimethylpyridine, 3,5-dimethylpyridine, 4-methylpyridine, 2-methylpyridine, 3-methylpyridine, 2,3-dimethylpyridine, 2-methyl-5-ethylpyridine, 3-ethylpyridine and 2-methylaminopyridine. Solid ammonium chloroacetate and chloroacetic acid are used as raw materials, and mixed crystal solids of glycine and ammonium chloride are obtained through an ammoniation reaction in a water solution. The water solution containing the catalyst can be circularly used. A glycine product and a byproduct (ammonium chloride) are prepared from the mixed crystal of glycine and ammonium chloride by adopting an electrodialysis membrane separation or alcohol precipitation separation method.

The invention discloses a production process of glycine, and belongs to the technical field of glycine production. Comprising the following steps: (1) adding acetic acid and chlorine into a chlorination reactor to react to generate chloroacetic acid and generate tail gas; (2) adding chloroacetic acid into an ammoniation reactor for reaction to generate ammoniation liquid, and purifying to obtain a glycine product and methanol mother liquor; (3) enabling the tail gas generated in the step (1) to pass through a cooler, so that acetic acid and acetyl chloride in the tail gas are condensed and recycled for chlorination reaction; (4) the uncondensed tail gas enters a desulfurization and dechlorination device to generate sulfuryl chloride, and the sulfuryl chloride is condensed and reused for chlorination reaction; meanwhile, recovering hydrogen chloride gas; and (5) the hydrogen chloride gas enters a hydrochloric acid absorption device to prepare a hydrochloric acid solution, and the hydrogen chloride gas which is not absorbed is mixed with the methanol mother liquor for neutralization reaction. The method has the characteristics of safety, reliability, energy conservation, emission reduction, low consumption of sulfur and acetic acid raw materials, high product quality and the like.