55 results about "Oxidative cleavage" patented technology

The invention provides medium-high molecular weight high-activity polyisobutene and a preparation method thereof, and the preparation method comprises the following steps: mixing hydrogen peroxide and a butyl rubber solution, and reacting for 0.5-20 hours at 20-80 DEG C under the catalytic action of a catalyst to obtain epoxidized butyl rubber; dissolving epoxidized butyl rubber to obtain an epoxidized butyl rubber solution; adding an oxidative cracking reagent into the epoxidized butyl rubber solution, and reacting at 0-80 DEG C for 0.5-20 hours to obtain a polyisobutylene solution; the medium-high molecular weight high-activity polyisobutene has the characteristics of high molecular weight, narrow distribution and higher end group activity, and can be applied to the application fields of traditional high-activity polyisobutene such as additives of lubricating oil, fuel oil, rubber and the like; and the product can be used as a sealing material, a waterproof water-retaining agent, a rubber and plastic modifier and the like, can meet wider application requirements, and has good industrial application value.

The invention relates to the technical field of high polymer materials, in particular to a low-viscosity self-curing polyurethane acrylate composition and a preparation method thereof.The low-viscosity self-curing polyurethane acrylate composition is prepared from, by mass, (a) 50-80 parts of polyurethane acrylate prepolymer; (b) 1-10 parts of functional particles; (c) 10-30 parts of a reactive diluent; (d) 0.1-2 parts of a visible light initiator; (e) 0.1-2 parts of a leveling agent; and (f) 0.1-1 part of a deoxidizing auxiliary agent. According to the invention, light response is expanded to a visible light wave band, natural light can trigger free radical polymerization and disulfide bond oxidative cleavage through component and structural design to realize controllable release of water, the system viscosity of an acrylate group is further reduced to 1500mPa. S or below, and the adhesive property and weather resistance are better after curing.

The invention relates to the technical field of biomedical materials, and discloses a degradable non-woven fabric and a preparation process thereof, the non-woven fabric is prepared from polylactic acid, polycaprolactone, periodate, a copolyester oligomer containing a cis-1, 2-cyclohexanediol structural unit, and a solid biocompatible weakly alkaline salt; the preparation process comprises the following steps: mixing the components, and performing melt blending and melt-blowing spinning to prepare the non-woven fabric. The periodate and the copolyester oligomer are used as latent reaction precursors, the alkalescent salt is used as a pH regulating agent, when the non-woven fabric is in contact with an aqueous environment, the alkalescent salt is dissolved out to establish an alkalescent microenvironment, the periodate is promoted to carry out oxidative cracking on the copolyester oligomer, and thus the aldehyde compound with antibacterial activity is generated in situ. According to the invention, the on-demand generation of antibacterial substances is realized, so that the non-woven fabric has high antibacterial rate and low cytotoxicity, and the technical problem that the activity and safety of a traditional antibacterial material are difficult to balance is solved.

The invention provides a gene, a carrier, a protein and application of split-ring loganin synthase in uncaria rhynchophylla, and belongs to the technical field of gene engineering. The invention provides gene sequences and coding amino acid sequences of three UrCYP72A enzyme elements in uncaria rhynchophylla. The host cell constructed by the invention can induce expression of UrCYP72A enzyme, and the three proteins can catalyze oxidative cleavage of loganin C7-C8 to generate iridoid compound biosynthesis key precursor split-ring loganin. According to the present invention, the key residues participating in the combination of the loganin CYP72A1177, the CYP72A1178 and the CYP72A1179 are analyzed through molecular docking and rational mutation, and the catalytic potential of the loganin CYP72A1177, the CYP72A1178 and the CYP72A1179 is improved by widening the substrate inlet and enhancing the substrate binding force; the key precursor split-ring loganin of the rhynchophylline can be prepared by serially connecting UrLAMT and UrCYP72s genes in the body of the nicotiana benthamiana.

This invention relates to a process for the recovery of cobalt ions and tungstic acid and / or its derivatives from aqueous solutions, such as in particular the spent catalytic waters deriving from processes for the oxidative cleavage of vegetable oils. In particular this invention relates to a process for the recovery of cobalt ions and tungstic acid and / or its derivatives which provides for the use of cation-exchange resins.

Provided is a method for producing a compound represented by General Formula (I) through oxidative cleavage of a compound of Formula (II), which is a bicyclic tetrasubstituted olefin compound. This method is for producing a compound represented by General Formula (I), including a step of obtaining a compound represented by General Formula (I) through oxidative cleavage of a compound represented by General Formula (II) using an oxidant in the presence of an additive represented by General Formula (III).

The invention discloses a method for directionally preparing high-purity azelaic acid from oleic acid based on a micro-channel reactor, which comprises the following steps: mixing oleic acid and hydrogen peroxide dissolved with a catalyst, and feeding the mixture into the micro-channel reactor for oxidative cracking reaction to obtain oxidation liquid mainly containing the azelaic acid and the oleic acid; standing and layering the oxidation liquid to obtain a water phase A and an oil phase A; hot water is introduced into the oil phase A containing the nonanoic acid and the azelaic acid for extraction and liquid separation, and a water phase B and an oil phase B are obtained; fractionating the oil phase B to obtain high-purity nonanoic acid; cooling and crystallizing the water phase B to obtain a crude azelaic acid product, and melting and evaporating the crude product to remove moisture to obtain high-purity azelaic acid. Based on the microchannel reactor, hydrogen peroxide is used as an oxidizing agent, oleic acid double bonds can be directionally oxidized through a catalyst system, oleic acid is directly oxidized and cracked into nonanoic acid and azelaic acid in a short time, the reaction efficiency can be greatly improved, the reaction time can be shortened, and the use of a solvent and a phase transfer catalyst is avoided; the method has the advantages of high selectivity, high safety and remarkable environmental protection.

Disclosed in the present invention is a method for directly preparing a phenol and an aldehyde or a ketone from an alkyl aromatic hydrocarbon as a raw material on the basis of a selective carbon-carbon bond oxidative cleavage reaction. The method is carried out on the basis of the following steps: mixing an alkyl aromatic hydrocarbon as represented by general formula (I) with a photocatalyst, hydrobromic acid, and an organic solvent and enabling the mixture to react under the conditions of oxygen as an oxidant and light irradiation to simultaneously prepare a phenol compound as represented by general formula (II) and a ketone or aldehyde compound as represented by general formula (III). In the present invention, bulk alkyl aromatic hydrocarbons are used as raw materials for reaction to produce phenol, aldehyde, and ketone organic chemical raw materials. Compared with traditional synthesis methods, the present invention has many advantages such as inexpensive and readily available catalysts, mild reaction conditions, simple operation, good selectivity, and high safety, is suitable for large-scale synthesis of phenols, p-cresol, cyclohexanone, etc., and exhibits wide application prospects.

The application discloses a phenolic acid compound and a preparation method and application thereof. The preparation method of the phenolic acid compound comprises the following steps: mixing a lignin raw material and a catalyst to perform an oxidative cleavage reaction, and obtaining the phenolic acid compound; and the lignin raw material contains C-type lignin. The application takes industrial waste lignin rich in C-type structure as a raw material, adopts a cheap and available commercial catalyst, and makes the lignin raw material perform the oxidative cleavage reaction, so that the yield of the obtained phenolic acid compound is high, the content of antioxidant components in the phenolic acid compound is also high, and the antioxidant performance is excellent, and the phenolic acid compound has wide application in the fields of medicine, beauty, food and functional materials. The application has the characteristics of novel route, greenness, high efficiency and sustainability, the route has low cost, and has high economic feasibility.

The invention relates to the technical field of oilfield development, and discloses a two-dimensional nano carbon quantum sheet based on oxidation cutting and a preparation method and application thereof. The method comprises the following steps: (1) grinding and mixing salt crystals and melamine to obtain a salt-melamine compound, then carrying out ultrasonic mixing on the salt-melamine compound and ethylene tar in an organic solvent, and evaporating the obtained mixture to obtain a carbon nanosheet precursor; and (2) carrying out carbonization treatment on the carbon nanosheet precursor in an inert atmosphere, then carrying out acid pickling on the obtained carbonized solid, and then sequentially carrying out suction filtration, drying and grinding to obtain the two-dimensional carbon nanosheet. The two-dimensional carbon nanosheet based on oxidation cutting prepared by the method provided by the invention can improve microscopic oil washing efficiency and macroscopic sweep efficiency through a dual mechanism of reducing interfacial tension and optimizing rock wettability, and ultimately improves crude oil recovery efficiency.

The present invention belongs to the field of chemical and chemical engineering technology, specifically a method for the continuous cleavage of alcohols into amides using a manganese oxide compound as a catalyst and molecular oxygen or air as an oxidant. The reaction is carried out at 130-150°C for 12 hours in the presence or absence of a solvent to oxidize the alcohols into amides. The catalyst can be recycled and reused at least nine times while maintaining excellent activity and selectivity. The catalyst is simple to prepare, inexpensive, highly selective, and environmentally friendly.

This invention discloses a three-component oxidation system and its application in the degradation of 4-hydroxyestradiol. Specifically, it discloses a 4,5-exogeneic dioxygenase, HedG1, associated with the oxidative cleavage of 4-OH-E1. This enzyme, supported by an electron transport chain composed of ferrugin HedG2 and ferrugin reductase HedG3, catalyzes the 4,5-seco meta-oxidative cleavage of 4-OH-E1, generating a meta-cleavage product of the A ring. The three-component dioxygenase system HedG1G2G3 based on HedG1 in this invention rapidly reduces the hormonal activity of cyclopentane polyhydrophenanthrene by disrupting the A ring of the cyclopentane polyhydrophenanthrene structure, which is beneficial for the remediation and treatment of environmental estrogen pollution.

The present invention discloses a tungsten-oxygen complex, a preparation method, and its application in olefin oxidative cracking and C-H bond oxidation, belonging to the technical field of metal coordination compound functional materials. The present invention utilizes bipyridine ligands and metallic tungsten to synthesize a novel tungsten-oxygen complex under H2O2 conditions. The complex has air-stable properties and can be used as a high-efficiency catalyst for olefin oxidative cracking and C-H bond oxidation to prepare carbonyl compounds. Compared with the prior art, the present invention has the following characteristics: (1) The catalyst provided by the present invention is a novel tungsten catalyst with a novel structure and is prepared for the first time; (2) The catalytic reaction is carried out under a homogeneous catalytic system and can be used not only for olefin oxidative cracking, but also for C-H bond oxidation to synthesize aldehydes and ketones; (3) The catalytic reaction uses oxygen or air as a green oxidant; (4) Abundant chemical raw materials (styrene derivatives, phenylethane derivatives) are used for the green synthesis of carbonyl compounds.

The method comprises the following steps: taking androstane-3-ketone-4-ene-17beta-carboxylic acid shown in a formula II as a raw material, carrying out decarboxylation hydroxylation, sulfonylation, elimination and double-bond oxidative cracking to prepare the exemestane intermediate shown in a formula VI, and then sequentially carrying out allylic oxidation, wittig reaction and 1, 2, 4-trimethyl-1, 3, 4-trimethyl-1, 3, 4-trimethyl-1, 3, 4-trimethyl-1, 3, 4-trimethyl-1, 3, 4-trimethyl-1, 3, 4-trimethyl-1, 3-trimethyl-1, 3, 4-trimethyl-1, 3, 4-trimethyl-1, 3-trimethyl-1, 3, 4-trimethyl-1, 3 the exemestane shown in the formula I is prepared through the step of 1, 2-site dehydrogenation. The method has the characteristics of simple process operation, mild conditions, high reaction yield and the like, and is suitable for industrial production.

The invention provides a method for preparing carboxylic ester by catalyzing alkyne oxidative cracking. According to the method, alkyne is taken as a substrate, oxygen is taken as an oxygen source, fatty alcohol (methanol, ethanol, propanol, isopropanol and butanol) is taken as an esterification reagent and solvent, and C-C triple bonds in alkyne molecules are subjected to oxidative cracking under the catalysis of nitrate (magnesium nitrate, ferric nitrate, cobalt nitrate, nickel nitrate, copper nitrate, zinc nitrate, aluminum nitrate and silver nitrate), nitric acid or NO2 and are converted into carboxylic ester. The reaction temperature is 60-100 DEG C, the reaction time is 2-30 hours, and the molar ratio of the substrate to nitrate in the catalytic reaction is 1: 0.2. Due to the fact that the catalytic reaction is high in selectivity, high in yield and few in by-product, the yield can reach 90% or above, and the method has the advantages of being high in atom utilization efficiency, economical, environmentally friendly and good in application prospect.

The invention discloses high-oleic-acid sunflower seed oil and a preparation method thereof, and belongs to the technical field of deep processing and refining of vegetable fat. According to the method, polyunsaturated fatty acid in triglyceride is preferentially converted into low-boiling-point fatty acid alkyl ester through selective enzymatic alcoholysis / ester exchange reaction, volatility difference is constructed, and directional enrichment of oleic acid components and segmented removal of low-boiling-point impurities are achieved through multi-stage short-path molecular distillation. According to the method, the content of oleic acid in the sunflower seed oil can be increased from 60-75% to 80-90%, the content of linoleic acid can be reduced from 15-30% to 5-12%, meanwhile, free fatty acid, peculiar smell precursors and oxylysate are effectively removed, the oxidation stability of the product is excellent, and the retention rate of nutritional ingredients is high. The linoleate-rich fraction generated in the technical process can be used as a high-added-value byproduct, so that the synergistic value increase of the main and by-products is realized.

The present invention relates to a synthetic gene cluster of an enfumafungin antibiotic and a synthetic method therefor. Specifically, in the present invention, key functional genes in the linking of a β-D-glucopyranose at position C3 of a fernane-type framework, the oxidation at position C2 into α-OH, the oxidative cleavage of ring E at C19-C20, and the acetylation of hydroxyl at position C2 during the biosynthesis of an enfumafungin antibiotic, i.e. fuscoatroside, are isolated, wherein the genes are named fsoA, fsoD, fsoE and fsoF, respectively. The present invention also provides encoding polypeptides thereof. Provided in the present invention are an artificial fusion enzyme gene, i.e. efuA(TC)fsoA(GT); and on the basis of the artificial fusion enzyme gene, the heterologous expression of four genes, i.e. efuA(TC)fsoA(GT), fsoD, fsoE and fsoF, can synthesize an enfumafungin precursor (13). The present invention clarifies an FsoE-mediated C-C bond breaking function of a P450 enzyme, and provides a key catalytically active residue of FsoE. The present invention reports the biosynthetic pathway of such compound for the first time, and establishes an important foundation for the green and efficient synthesis of the compound.

The application discloses a method for preparing carboxylic acid ester compounds by oxidizing and breaking carbon-carbon double bonds of olefin compounds. The method comprises the following steps: adding olefin compounds, an additive and a nitrogen-doped mesoporous carbon loaded cobalt-based catalyst into a primary aliphatic alcohol solvent, placing the mixture into a pressure container, and introducing an oxygen source gas with a pressure of 0.5-0.9 MPa at a reaction temperature of 80-150 DEG C. The product after the reaction is a carboxylic acid ester compound. The method has a wide application range, the reaction conditions are easy to control, the catalyst can be recycled, the post-treatment is simple, and the method is suitable for industrial production.

The invention relates to a method for the selective electro-oxidative fragmentation of lignin using an electrochemical system, comprising the following steps: (i) synthesis of a nickel-cobalt electrocatalyst; (ii) obtaining an anode coated with the electrocatalyst; and (iii) selective fragmentation and oxidation of solubilised lignin in an electrochemical reactor comprising said anode, in which vanillic acid and syringic acid are obtained as preferred products.

This invention relates to the field of biomedical materials technology, and discloses a biodegradable nonwoven fabric and its preparation process. The nonwoven fabric is made of components including polylactic acid, polycaprolactone, periodate, a copolyester oligomer containing cis-1,2-cyclohexanediol structural units, and a solid biocompatible weakly basic salt. The preparation process includes mixing the components and then melt-blending and melt-blowing to prepare the nonwoven fabric. In this invention, periodate and the copolyester oligomer serve as latent reaction precursors, and the weakly basic salt acts as a pH regulator. When the nonwoven fabric comes into contact with an aqueous environment, the weakly basic salt dissolves, establishing a weakly basic microenvironment that promotes the oxidative cleavage of the copolyester oligomer by periodate, thereby generating aldehyde compounds with antibacterial activity in situ. This invention achieves on-demand generation of antibacterial substances, enabling the nonwoven fabric to possess both high antibacterial rates and low cytotoxicity, solving the technical problem of balancing activity and safety in traditional antibacterial materials.

This invention discloses an oleic acid oxidative cracking catalyst, its preparation method, and its application, belonging to the field of catalyst preparation technology. The catalyst for the oxidative cracking of oleic acid to azelaic acid is prepared by: uniformly mixing phosphotungstic acid with an organic onium salt, and then ball milling the mixture in a ball mill jar. The preparation method is simple, generates no waste, and produces a catalyst with high yield and high activity. In the process of oleic acid cracking to azelaic acid, the conversion rate of oleic acid reaches 100%, and the selectivity of azelaic acid reaches 96%.

The present disclosure provides a process for oxidative cleavage of Trolox amides. More particularly, the present disclosure provides a process for the preparation of a compound of formula I: # imgabs0 # comprising the step of contacting an oxidizing agent with a compound of formula II in a solvent, and the step of contacting a base with the solvent to promote a reaction between the compound of formula II and the oxidizing agent. # imgabs 1 # in the formula: R1, R2, R3, R4, R5, R6, R7, R8, and R9 each independently represent a hydrogen atom, a halogen, an optionally substituted C1-6 alkyl group, an optionally substituted C1-6 alkoxy group, or-C (= O) NRARB, and RA and RB each independently represent a hydrogen atom, an optionally substituted C1-6 alkyl group, or an optionally substituted C1-6 alkoxy group.

The application discloses a method for catalytic oxidative cleavage of aromatic ether substances. The method is that aromatic ether substances, metal-base composite catalysts and water medium are placed in an autoclave, and oxygen-containing gas is filled for hydrothermal reaction; the metal-base composite catalysts contain metal active components and base active components, wherein the metal active components are ruthenium, palladium, platinum, copper or cobalt, and the base active components are magnesium oxide, barium oxide or calcium oxide; the method can catalytically oxidize and cleave the aromatic ether substances into high-value-added small organic molecules such as phenols and carboxylic acids with high selectivity, and does not need to use organic solvent medium and add a large amount of inorganic base, and has the characteristics of simple process, high product added value and the like, and can produce important economic value and social benefits.

The invention discloses a heteroatom-doped cobalt nanoparticle carbon-based catalyst as well as a preparation method and application thereof, and relates to the technical field of chemical engineering. The preparation method comprises the following steps: firstly, dissolving and heating cellulose to form sol, then adding cobalt salt and a nitrogen source (or additionally adding a phosphorus source / sulfur source), and carbonizing the obtained sol system to obtain the heteroatom-doped cobalt nanoparticle carbon-based catalyst. The prepared catalyst can efficiently catalyze oxidative cracking of a lignin model compound, phenols and functionalized esters are generated in a high-selectivity mode, and an economical and green route is provided for high-value utilization of lignin.

The application provides application of copper salt and alkaline metal salt, a photocatalyst for oxidative cleavage of aromatic hydrocarbon derivatives and a method for preparing benzoic acid derivatives, and relates to the technical field of plastic recycling. The application provides application of copper salt and alkaline metal salt (calcium chloride) with a molar ratio of 1:0-10 as a photocatalyst in photo-oxidative cleavage of aromatic hydrocarbon derivatives. When the copper salt and the alkaline metal salt are used in photo-oxidative cleavage of aromatic hydrocarbon derivatives, CuCl and chlorine free radicals generated by the copper salt (taking copper chloride as an example) under light irradiation, the chlorine free radicals act as hydrogen atom transfer reagents, activate C-H bonds of aromatic hydrocarbon derivatives and lignin model compounds to generate alkyl carbon free radicals, the alkyl carbon free radicals combine with O2 to form peroxide intermediates to obtain benzoic acid derivatives. The application also improves the activity of metal oxygen complex intermediates by using redox-inactive alkaline metal ions as Lewis acids, and further improves the yield of benzoic acid derivatives in cleavage products.

This invention discloses a method for the biosynthesis of high-purity L-threonate magnesium, belonging to the field of food fortification agents and biochemical synthesis technology. The invention uses L-xylorate calcium solution as a substrate, and obtains a purified L-threose solution through oxidative cleavage. Then, a complex dehydrogenase system composed of arabinose dehydrogenase, xylose dehydrogenase, and aldose dehydrogenase synergistically catalyzes the oxidation of L-threose to L-threonate. Finally, L-threonate magnesium is prepared by salt formation with magnesium hydroxide, crystallization, and drying. The purity of the obtained product is greater than 99.0%, the oxalic acid residue is less than 0.01%, the process is safe and environmentally friendly, and suitable for industrial production.

The invention relates to a synthetic gene cluster and a synthetic method of an amphetamine antibiotic. Specifically, key action genes for connecting beta-D-glucopyranose to the C3 site, oxidizing the C2 site into alpha-OH, oxidizing and cracking the E ring C19-C20 and acetylating the C2 site hydroxyl in biosynthesis of the amphetamine gold antibiotic fuscoatroside are separated and are respectively named as fsoA, fsoD, fsoE and fsoF, and the invention provides a coding polypeptide of the key action genes and the application of the key action genes in biosynthesis of the amphetamine gold antibiotic fuscoatroside in biosynthesis of the amphetamine gold antibiotic fuscoatroside in biosynthesis of the amphetamine gold antibiotic fuscoatroside in biosynthesis of the amphetamine gold antibiotic fuscoatroside in biosynthesis of the amphetamine gold antibiotic fuscoatroside. The invention provides an artificial fusion enzyme gene efuA (TC) fsoA (GT), and on the basis of the artificial fusion enzyme gene efuA (TC) fsoA (GT), four genes of efuA (TC) fsoA (GT), fsoD, fsoE and fsoF are subjected to heterologous expression, so that an ampelopsin precursor (13) can be synthesized. The invention clarifies a P450 enzyme FsoE mediated C-C bond breaking function, and provides a key catalytic activity residue of FsoE. The invention reports the biosynthesis pathway of the compound for the first time, and lays an important foundation for realizing green and efficient synthesis of the compound.

The present invention generally relates to the production of vanillin and related compounds (such as aromatic carboxylic acids, quinones, etc.) involving the oxidative cleavage of aromatic compounds (such as lignin, lignols, cinnamic acid and its derivatives, etc.) under mild reaction conditions. More specifically, the present invention provides processes for the production of vanillin involving the oxidative cleavage of an aromatic compound, such as lignin or ferulic acid, using a peroxide based oxidant, such as hydrogen peroxide, in the presence of a suitable catalysis, such as vanadium oxide.

The present application relates to the technical field of chemical engineering, and discloses a method for preparing aromatic aldehyde and aromatic acid from lignin. The method comprises the following steps: mixing lignin raw material with a heterogeneous solid catalyst, and generating aromatic aldehyde and aromatic acid through oxidative cleavage reaction; the lignin raw material contains C-type and G / S-type lignin; and the heterogeneous solid catalyst comprises nitrogen-doped activated carbon loaded with transition metal. The method provided by the present application uses waste seed shells of Euphorbiaceae plants rich in C / G / S-type lignin as raw material, has low raw material cost, and uses a heterogeneous solid catalyst which has low preparation cost and can be effectively separated from the product. The catalytic activity of the catalyst in the oxidative cleavage reaction is high. The method is a green and efficient method for preparing aromatic aldehyde and aromatic acid based on biomass, and is suitable for industrial production. The method provided by the present application can obtain valuable aromatic aldehyde and aromatic acid with high yield, and can be applied to the fields of food and medicine to meet market demand.

The invention discloses a tubular C3N4 heterojunction photocatalyst as well as a preparation method and application thereof, the method comprises the following steps: firstly, preparing tubular C3N4 (TCN) from urea and melamine as raw materials, reacting the TCN with H3PO4 to obtain H3PO4 modified TCN (P-TCN), and finally, introducing phosphotungstic acid (PW) to construct the heterojunction photocatalyst (PW / P-TCN). According to the PW / P-TCN catalyst prepared by the invention, O2 adsorption is enhanced, separation and transfer of a photo-generated carrier are improved, exposure of active sites is increased, and meanwhile, efficient reduction and oxidation capabilities of the catalyst are maintained. According to the method, PW / P-TCN is taken as a photocatalyst, acetonitrile is taken as a solvent, a xenon lamp is taken as a light source, oxidative cleavage of C-C bonds of a lignin model compound is realized in a room-temperature oxygen atmosphere, and aromatic monomer products such as benzoic acid and phenylacetaldehyde are obtained.