A medicament for treating vaginitis that can prevent lactobacilli in the vagina from being killed

A Lactobacillus, vaginitis technology, applied in the direction of antibacterial, antifungal, drug combination, etc., can solve the problems of recurrent disease, destruction of vaginal micro-ecological environment, normal flora imbalance, etc., to maintain the vaginal micro-ecological environment , improve local immunity, the effect of good clinical application prospects

Active Publication Date: 2019-09-10
朱有名
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, the treatment of vaginitis is mainly based on sterilization and anti-inflammation. The commonly used treatment methods include drug vaginal douching, local drug delivery, oral administration, etc., but the main active ingredients of the drugs used are antibiotics, which has a serious defect in the treatment of vaginitis. That is, while killing or inhibiting pathogenic bacteria, it also kills or inhibits the growth of Lactobacillus, causing the destruction of the vaginal micro-ecological environment and the imbalance of normal flora.

Method used

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  • A medicament for treating vaginitis that can prevent lactobacilli in the vagina from being killed

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Example 1: A medicament for treating vaginitis that can avoid the killing of lactobacilli in the vagina and its preparation

[0017] Pharmaceutical formulation: 260 grams of wood vinegar, carbomer 200, 80 grams of Tween, 10 grams of propylene glycol, 2 grams of disodium ethylenediaminetetraacetic acid, 58 grams of triethanolamine, and 390 grams of water.

[0018] Preparation of the agent: take the carbomer and pass it through a sieve of 100 meshes or more for use; heat the designed amount of water to 50-65°C, dissolve the disodium ethylenediaminetetraacetic acid in the water while stirring, and then add the carbomer into it , Make it swell into a uniform colloid; dilute the triethanolamine with the remaining amount of water, slowly add it to the colloid under heat preservation and stirring, then add Tween and propylene glycol under stirring, continue to heat preservation and stirring to make it completely dissolved, stirring Mix evenly and make the pH value 4.8, then pack it...

Embodiment 2

[0019] Example 2: A medicament for treating vaginitis that can avoid the killing of lactobacilli in the vagina and its preparation

[0020] Pharmaceutical formula: 10 grams of bamboo vinegar, 2 grams of glycerin gelatin, 0.01 grams of Tween, and 88 grams of water.

[0021] Pharmaceutical preparation: add bamboo vinegar liquid to water, adjust pH to 4.5, heat to 60-70°C, add glycerin gelatin to it, add Tween after it is dissolved, stir evenly, and distribute.

Embodiment 3

[0022] Example 3: A medicament for treating vaginitis that can avoid the killing of lactobacilli in the vagina and its preparation

[0023] Pharmacy formula: 10 grams of wood vinegar, 1 gram of carbomer, 1 gram of glycerin, and 88 grams of water.

[0024] Medicament preparation: add wood vinegar to water, adjust pH to 3.5, heat to 60-70°C, add carbomer into it, add glycerin after it is dissolved, stir well, and distribute.

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Abstract

The invention discloses a medicament for treating vaginitis and capable of preventing lactobacillus in a vagina from being killed. The pH value of the medicament is 2.5 to 6.5, and the medicament is prepared by mixing bamboo vinegar or / and wood vinegar with a matrix and water, wherein in percentage by weight, the bamboo vinegar or / and wood vinegar accounts for 2 to 50 percent of the weight of the medicament, and the matrix accounts for 0.1 to 35 percent of the weight of the medicament; the water accounts for the balance percentage of the weight of the medicament. An experiment shows that the medicament disclosed by the invention has a specific killing or suppressing effect on harmful pathogenic bacteria, but cannot kill or suppress probiotics and lactobacillus; the shortcoming that vaginitis is mainly treated with relevant medicaments such as antibiotic is overcome; the ecological environment of the vagina is well maintained, the vagina self-cleaning effect of the lactobacillus is developed, and local immunity of the vagina is enhanced; the medicament is expected to be an optimal medicament for treating the vaginitis and has a good clinical application prospect.

Description

Technical field [0001] The invention relates to an antibacterial agent, in particular to an agent for treating vaginitis that can prevent the lactobacillus in the vagina from being killed. Background technique [0002] Vaginitis is the most common disease of female genital tract infections, and it is the general term for various vaginal mucosal inflammatory diseases caused by different pathogens. Vaginitis has more than ten types according to its etiology and pathogens, including trichomonas vaginitis, vulvovaginal candida (formerly known as vulvovaginal candidiasis), bacterial vaginosis, aerobic vaginitis, Senile vaginitis, infantile vaginitis, viral vaginitis, amoebic vaginitis, drug-induced vaginitis, emphysema vaginitis, radiation vaginitis, allergic vaginitis, chemical vaginitis, etc. The most common are the first three. [0003] Under normal conditions, there are bacteria, fungi, viruses, protozoa, and other microorganisms in the vagina. The main resident bacteria are Lacto...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61K9/08A61K47/32A61K47/36A61K47/42A61P15/02A61P31/04A61P31/10A61P33/02A61K36/00A61K31/19
Inventor 朱有名潘虹朱晓蕾
Owner 朱有名
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