Medicament for treating vaginitis and capable of preventing lactobacillus in vagina from being killed

A technology for Lactobacillus and vaginitis, applied in antibacterial drugs, antifungal agents, pharmaceutical formulations, etc., can solve the problems of normal flora imbalance, recurrent disease, and destruction of vaginal micro-ecological environment, so as to maintain vaginal micro-ecological environment , improve local immunity, good clinical application prospects

Active Publication Date: 2016-07-06
朱有名
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, the treatment of vaginitis is mainly based on sterilization and anti-inflammation. The commonly used treatment methods include drug vaginal douching, local drug delivery, oral administration, etc., but the main active ingredients of the drugs used are antibiotics, which has a serious defect in the treatment of vaginitis. That is, while killing or inhibiting pathogenic bacteria, it also kills or inhibits the growth of Lactobacillus, causing the destruction of the vaginal micro-ecological environment and the imbalance of normal flora.

Method used

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  • Medicament for treating vaginitis and capable of preventing lactobacillus in vagina from being killed

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Example 1: A medicament for treating vaginitis that can avoid the killing of Lactobacillus in the vagina and its preparation

[0017] Pharmaceutical formula: 260 grams of wood vinegar, 200 grams of carbomer, 80 grams of Tween, 10 grams of propylene glycol, 2 grams of disodium edetate, 58 grams of triethanolamine, and 390 grams of water.

[0018] Preparation of medicine: take carbomer and pass it through a sieve of more than 100 mesh for use; take the designed amount of water and heat it to 50-65°C, under heat preservation and stirring, first dissolve disodium ethylenediaminetetraacetic acid in water, and then add carbomer to it , to make it swell into a uniform colloid; dilute triethanolamine with the remaining amount of water, slowly add it to the above colloid under heat preservation and stirring, then add Tween and propylene glycol into it while stirring, continue heat preservation and stirring to dissolve completely, and stir Mix evenly, and make the pH value 4.8, t...

Embodiment 2

[0019] Example 2: A medicament for treating vaginitis that can avoid the killing of Lactobacillus in the vagina and its preparation

[0020] Medicinal formula: 10 grams of bamboo vinegar, 2 grams of glycerin gelatin, 0.01 grams of Tween, and 88 grams of water.

[0021] Medicament preparation: add bamboo vinegar to water, adjust pH to 4.5, heat to 60-70°C, add glycerin gelatin to it, add Tween after it dissolves, stir evenly, pack separately.

Embodiment 3

[0022] Example 3: A medicament for treating vaginitis that can avoid the killing of Lactobacillus in the vagina and its preparation

[0023] Medicinal formula: 10 grams of wood vinegar, 1 gram of carbomer, 1 gram of glycerin, and 88 grams of water.

[0024] Medicament preparation: Add wood vinegar to water, adjust pH to 3.5, heat to 60-70°C, add carbomer into it, add glycerin after it dissolves, stir evenly, and pack separately.

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Abstract

The invention discloses a medicament for treating vaginitis and capable of preventing lactobacillus in a vagina from being killed. The pH value of the medicament is 2.5 to 6.5, and the medicament is prepared by mixing bamboo vinegar or / and wood vinegar with a matrix and water, wherein in percentage by weight, the bamboo vinegar or / and wood vinegar accounts for 2 to 50 percent of the weight of the medicament, and the matrix accounts for 0.1 to 35 percent of the weight of the medicament; the water accounts for the balance percentage of the weight of the medicament. An experiment shows that the medicament disclosed by the invention has a specific killing or suppressing effect on harmful pathogenic bacteria, but cannot kill or suppress probiotics and lactobacillus; the shortcoming that vaginitis is mainly treated with relevant medicaments such as antibiotic is overcome; the ecological environment of the vagina is well maintained, the vagina self-cleaning effect of the lactobacillus is developed, and local immunity of the vagina is enhanced; the medicament is expected to be an optimal medicament for treating the vaginitis and has a good clinical application prospect.

Description

technical field [0001] The invention relates to an antibacterial agent, in particular to an agent for treating vaginitis which can prevent lactobacilli in the vagina from being killed. Background technique [0002] Vaginitis is the most common disease of female reproductive tract infection, and it is a general term for various inflammatory diseases of vaginal mucosa caused by different pathogens. There are more than ten kinds of vaginitis according to its etiology and pathogens, including trichomonas vaginitis, vulvovaginal candidiasis (formerly known as vulvovaginal candidiasis), bacterial vaginosis, aerobic vaginitis, Senile vaginitis, infantile vaginitis, viral vaginitis, amebic vaginitis, drug-induced vaginitis, emphysema vaginitis, radiation vaginitis, allergic vaginitis, chemical vaginitis, etc. The most common are the first three. [0003] Under normal conditions, there are bacteria, fungi, viruses, protozoa and other microorganisms in the vagina. The main resident ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61K9/08A61K47/32A61K47/36A61K47/42A61P15/02A61P31/04A61P31/10A61P33/02A61K36/00A61K31/19
Inventor 朱有名潘虹朱晓蕾
Owner 朱有名
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