Breast patch and preparation method thereof

A patch and breast technology, applied in medical science, surgery, etc., can solve the problems of weak muscle tissue, exacerbation of infection and rejection, displacement of prosthesis, etc., and achieve the effect of reducing morbidity, reducing rejection and inducing regeneration

Inactive Publication Date: 2016-07-13
SHAANXI RUISHENG BIOTECH
View PDF3 Cites 9 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Especially for Ogilvy & Mather removal patients and breast cancer patients, the breast muscle tissue is usually weak due to the removal of a large area of ​​breast tissue. After the breast prosthesi

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Breast patch and preparation method thereof
  • Breast patch and preparation method thereof
  • Breast patch and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0041] On the other hand, the embodiment of the present invention provides a method for preparing a breast patch as described above, see Figure 5 ,include:

[0042] Step 1) Remove the adipose tissue and connective tissue of the mammalian membrane tissue to obtain the membrane tissue after preliminary treatment;

[0043] Step 2) Soak the preliminarily processed membrane tissue in an alkali solution for decellularization treatment to obtain a decellularized membrane tissue;

[0044] Step 3) Soak the decellularized membrane tissue in an organic solvent for degreasing treatment to obtain a defatted membrane tissue;

[0045] Step 4) Surface modification and drying of the defatted membrane tissue to obtain a breast patch.

[0046] Since the mammalian membrane tissue itself has a double-layer structure with a dense layer and a loose layer, decellularizing the animal membrane tissue can retain the natural double-layer structure of the animal membrane tissue.

[0047] An embodiment of the prese...

Example Embodiment

[0089] Example 1

[0090] S101. Remove the fat tissue and connective tissue on the surface of the bovine pericardium, clean the surface foreign body, and obtain the bovine pericardium after the preliminary treatment;

[0091] S102. Soak the bovine pericardium after the preliminary treatment in 30% hydrogen peroxide solution for 3 hours for disinfection, then wash with normal saline for 1 hour, and then wash with water to a pH of 6.0.

[0092] S103: Soak the bovine pericardium obtained in step S102 with 5 times the amount of 1M sodium hydroxide for 0.5 h to obtain a decellularized bovine pericardium;

[0093] S104. Wash the decellularized bovine pericardium with three parts of phosphate buffer 15 times the mass of the decellularized bovine pericardium for 15 minutes, so that the pH of the water on the bovine pericardium is The value is 6.0;

[0094] S105. The bovine pericardium obtained in step S104 is defatted by shaking with 5 times the amount of isopropanol for 4 hours to obtain a de...

Example Embodiment

[0103] Example 2

[0104] S101. Remove the fat tissue and connective tissue on the surface of the sheep small intestine mucosa, clean the surface foreign body, and obtain the sheep small intestine mucosa after preliminary treatment;

[0105] S102, the sheep small intestine mucosa after the preliminary treatment is immersed in 60% hydrochloric acid solution for 0.5 h for disinfection, then washed with phosphate buffer solution for 2 h, and then washed with water to a pH value of 7.0.

[0106] S103. Soak the sheep small intestine mucosa of step S102 with 5 times the amount of 0.5M sodium hydroxide for 3 hours to obtain a decellularized sheep small intestine mucosa;

[0107] S104. Wash the decellularized sheep intestinal mucosa with three parts of phosphate buffer 15 times the mass of the decellularized sheep intestinal mucosa for 12 minutes, so that the pH of the water on the sheep intestinal mucosa is 8.0 ;

[0108] S105. The sheep small intestinal mucosa obtained in step S104 is shaken...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention relates to the technical field of tissue engineering, in particular to a breast patch and a preparation method thereof.The breast patch is implanted between a breast prosthesis and an organism, rejection reaction of the organism can be reduced, the morbidity of capsule contracture is reduced, pain of patients is relieved, a supporting and fixing function can be achieved, and the prosthesis is prevented from moving or drooping.The breast patch is membrane tissue of a two-layer structure.The two-layer structure comprises a compact layer and a loose layer.The compact layer is formed by densely distributing collagen bundles in a staggered mode.The loose layer is formed by loosely distributing collagen bundles in a staggered mode.

Description

technical field [0001] The invention relates to the technical field of tissue engineering, in particular to a breast patch and a preparation method thereof. Background technique [0002] In recent years, breast plastic surgery is one of the most common types of plastic surgery. The most common types of breast plastic surgery are: breast augmentation, breast sagging correction, breast reconstruction and breast reconstruction; in these breast plastic surgery , It is usually necessary to implant breast prostheses into the pectoralis major muscle. After surgery, patients often experience rejection of foreign bodies, resulting in capsular contractures such as breast stiffness and pain. Especially for Ogilvy patients and breast cancer patients, usually due to the removal of large areas of breast tissue, the breast muscle tissue is relatively weak, and after the breast prosthesis is implanted, complications such as prosthesis displacement and sagging will occur. These complication...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61L31/00A61L31/04A61L31/14
CPCA61L31/005A61L31/044A61L31/14C08L89/00
Inventor 张锐利
Owner SHAANXI RUISHENG BIOTECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap