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Oral care composition, and preparation method and application thereof

An oral care and composition technology, applied in the field of medicine, can solve the problems of periodontitis, less irritation, stomatitis and glossitis, achieve good bacteriostatic effect, less irritation, and prevent periodontal disease Effect

Inactive Publication Date: 2016-08-17
SHANDONG PROVINCIAL HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, bacteriostasis is not the only indicator for oral care products. There are many different types of medicated toothpaste on the market. Unfortunately, many people who often use medicated toothpaste still inevitably suffer from periodontitis and other diseases , this is because most of the existing drug toothpastes contain alkaloids and strong irritating substances. Long-term use will not only damage the oral mucosa, but also cause gingivitis, stomatitis and glossitis, etc.
Chinese herbal medicine is relatively safe and less irritating, but the antibacterial effect is not ideal

Method used

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  • Oral care composition, and preparation method and application thereof
  • Oral care composition, and preparation method and application thereof
  • Oral care composition, and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] The composition for oral care of the present invention is composed of the following components: 1kg of honeysuckle, 2kg of dandelion leaves, 2kg of Angelica dahurica, 3kg of Houttuynia cordata, and 0.01kg of isopropylmethylphenol.

[0024] The preparation method of this oral care composition comprises steps:

[0025] 1) Mix the honeysuckle flower, light bamboo leaves, Angelica dahurica and Houttuynia cordata with 16 kg of 60% ethanol aqueous solution by volume, reflux for 1 hour, and filter to obtain the filtrate;

[0026] 2) continue to mix the obtained filter residue with 2 times the weight of the filter residue in 60% ethanol aqueous solution by volume and reflux for 1 hour, filter to obtain the filtrate, and combine it with the filtrate obtained in step 1);

[0027] 3) Add the formulated amount of isopropyl methylphenol to the filtrate obtained in step 2), oscillate ultrasonically for 10 minutes, heat to reflux for 1 hour, and concentrate while hot to a relative den...

Embodiment 2

[0029] The composition for oral care of the present invention is composed of the following components: 3 kg of honeysuckle, 5 kg of dandelion leaves, 4 kg of angelica dahurica, 8 kg of houttuynia cordata, and 0.05 kg of isopropyl methylphenol.

[0030] The preparation method of this oral care composition comprises steps:

[0031] 1) Mix honeysuckle flower, light bamboo leaves, Angelica dahurica and Houttuynia cordata with 100kg of 90% by volume ethanol aqueous solution, reflux for 3 hours, and filter to obtain the filtrate;

[0032] 2) Continue to mix the obtained filter residue with 5 times the weight of the filter residue in 90% ethanol aqueous solution by volume and reflux for 3 hours, filter to obtain the filtrate, and combine it with the obtained filtrate in step 1);

[0033] 3) Add the formulated amount of isopropyl methylphenol to the filtrate obtained in step 2), oscillate ultrasonically for 15 minutes, heat to reflux for 3 hours, and concentrate while hot to a relativ...

Embodiment 3

[0035] The composition for oral care of the present invention is composed of the following components: 1 kg of honeysuckle, 3 kg of dandelion leaves, 3 kg of angelica dahurica, 5 kg of houttuynia cordata, and 0.02 kg of isopropyl methylphenol.

[0036] The preparation method of this oral care composition comprises steps:

[0037] 1) Mix honeysuckle flower, light bamboo leaves, Angelica dahurica and Houttuynia cordata with 36 kg of 80% by volume ethanol aqueous solution, reflux for 2 hours, and filter to obtain the filtrate;

[0038] 2) continue to mix the obtained filter residue with an aqueous ethanol solution with a volume percentage of 60-90% of 3 times the weight of the filter residue and reflux for 2 hours, filter to obtain a filtrate, and combine it with the filtrate obtained in step 1);

[0039] 3) Add the formulated amount of isopropyl methylphenol to the filtrate obtained in step 2), oscillate ultrasonically for 12 minutes, heat to reflux for 2 hours, and concentrate ...

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Abstract

The invention discloses an oral care composition, a preparation method thereof, and an application thereof in preparation of toothpastes or mouth washes. The oral care composition comprises, by weight, 1-3 parts of honeysuckle flower, 2-5 parts of Lophatherum gracile, 2-4 parts of dahurian angelica root, 3-8 parts of Herba Houttuyniae and 0.01-0.05 parts of isopropyl methylphenol. The composition adopting Chinese herbal medicinal components as main components has the advantage of integral mildness, small irritation, realization of a very good effect through synergism of Chinese herbal medicines and isopropyl methylphenol, and good continuous use safety.

Description

technical field [0001] The invention relates to a composition for oral care, in particular to a composition for oral care and a preparation method and application thereof. It belongs to the field of medical technology. Background technique [0002] The incidence of oral diseases in our country is very high, but residents lack oral health knowledge and awareness of disease prevention is relatively weak, and they still cannot form a good habit of regular oral examination in a short period of time. The composition for oral care is convenient to use and easy to popularize, can help people take care of the oral cavity during the long transitional development period of oral care, and effectively reduce the occurrence of oral diseases. [0003] Periodontal disease, dental caries and halitosis are relatively common oral diseases, which are caused by various bacteria in the oral cavity. Therefore, killing bacteria is an effective means to prevent and improve oral diseases. [0004]...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61K8/97A61K8/34A61P1/02A61Q11/00A61K31/05
CPCA61K36/355A61K8/347A61K8/97A61K31/05A61K36/232A61K36/78A61K36/899A61K2236/333A61K2236/39A61K2236/51A61Q11/00A61K2300/00
Inventor 侯亚丽张东升李凤霞王庆华
Owner SHANDONG PROVINCIAL HOSPITAL
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