Method for extracting glabrene and high-purity glabridin from Glycyrrhiza glabra by using ultrasonic continuous countercurrent apparatus

A technology of licorice glabra and glabridin, applied in countercurrent extraction, chemical instruments and methods, separation methods, etc., can solve the problems of high extraction temperature, large amount of waste gas and waste water, and low extraction rate

Inactive Publication Date: 2016-08-17
DAXINGANLING PERFECTION NOBILITY FRIGID ZONE BIO TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] In the prior art, the production of glycyrrhizic acid and glabridin is mostly extracted with relatively original multifunctional extraction tank thermal reflux macroporous resin. Extraction with this method requires high extraction temperature and low extraction rate, and, in During the production process, a large amount of waste gas and waste water will be generated, which will pollute the environment.

Method used

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Comparison scheme
Effect test

Embodiment 1

[0016] Embodiment 1: The present invention provides a kind of method that utilizes ultrasonic continuous countercurrent equipment to extract glycyrrhizic acid and glabridin in Glycyrrhizae glabra, and its process steps are as follows:

[0017] 1. 100kg of Glycyrrhizae glabra powder that has been screened, removed, and crushed to 30 meshes is delivered to the feeding device of the ultrasonic continuous countercurrent equipment through a quantitative feeder, and is input into the extraction tank from the feeding port, and at the same time The extraction solvent is an extraction solvent with a ratio of licorice glabra and extraction solvent weight kilogram to volume liter of 1:7. This specific embodiment adopts licorice and extraction solvent weight kilogram to volume liter. The ratio is 1:6 extraction solvent 600L, The specific embodiment of the extraction solvent is that 50% ethanol and 20% ammonia water are mixed into an extraction solvent in a ratio of 1:0.01 by weight, heated...

Embodiment 2

[0022] Embodiment 2: The present invention provides a kind of method that utilizes ultrasonic continuous countercurrent equipment to extract glycyrrhizic acid and glabridin in Glycyrrhizae glabra, and its process steps are as follows:

[0023] 1. 100kg of Glycyrrhizae glabra powder after screening, removing impurities and crushing to 35 meshes is delivered to the feeding device of the ultrasonic continuous countercurrent equipment through the quantitative feeder, and is input into the extraction tank from the feeding port, and at the same time The extraction solvent is the extraction solvent of 1:9 according to the ratio of licorice glabra and extraction solvent weight kilograms to volume liters, 900L. This specific embodiment of the extraction solvent is 1 to 0.1 by weight ratio of 70% ethanol and 28% ammonia water The ratio is mixed into an extraction solvent, heated to 80°C by a heat exchanger, and input into the extraction tank from the waste residue end of the ultrasonic c...

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Abstract

Glycyrrhiza glabra is a perennial herb with strong roots and rhizomes, 0.5‑3cm in diameter, brown root bark, yellow inside, and sweet taste. There are abundant wild resources in the Greater Khingan Mountains and Inner Mongolia. In the roots and rhizome tissue cells of Glycyrrhizae glabra, there are functional components with strong anti-oxidant activity for skin depigmentation and lightening spots, and they are also the main components, namely glycyrrhizic acid (Glabrene) and glabridin (Glabridin). Because glabridin has the function of skin depigmentation and light spots with strong anti-oxidation activity, it has begun to receive attention, recognition and utilization from the foreign cosmetics industry. Low, low purity, low raw material utilization rate, high energy consumption cost for secondary refining and purification, etc., crude glabridin mostly exists in the domestic market. The invention provides a technical scheme for extracting glycyrrhizic acid and high-purity glabridin from licorice glabra by using ultrasonic continuous countercurrent equipment, which can increase the yield of finished products by 30%.

Description

technical field [0001] The invention relates to an extraction method, in particular to a method for extracting glycyrrhizic acid and glabridin in licorice glabra by using ultrasonic continuous countercurrent equipment. Background technique [0002] In the prior art, the production of glycyrrhizic acid and glabridin is mostly extracted with relatively original multifunctional extraction tank thermal reflux macroporous resin. Extraction with this method requires high extraction temperature and low extraction rate, and, in In the production process, a large amount of waste gas and waste water will be generated, which will pollute the environment. [0003] The technical problem to be solved by the present invention is to provide a technical scheme for extracting glycyrrhizic acid and glabridin in Glycyrrhizae glabra using ultrasonic continuous countercurrent equipment. On the equipment, glycyrrhizic acid and glabridin in Glycyrrhizae glabra were extracted countercurrently with ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01D11/02C07J63/00C07H15/256C07H1/08C07D493/04
CPCB01D11/0265B01D11/0292B01D2011/002C07D493/04C07H1/08C07H15/256C07J63/008
Inventor 刘巍
Owner DAXINGANLING PERFECTION NOBILITY FRIGID ZONE BIO TECH CO LTD
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