Medicine for treating stomach-yin deficiency type peptic ulcer and preparation method thereof

A technology for peptic ulcer and stomach yin deficiency, applied in the direction of digestive system, drug combination, medical formula, etc., can solve the problems of many side effects of antibiotics, unsatisfactory clinical curative effect, single treatment plan, etc., to achieve no toxic side effects, Effect of protecting gastric mucosa and increasing appetite

Inactive Publication Date: 2016-09-07
YANTAI MINWANG ELECTROMECHANICAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] However, Western medicine treats peptic ulcer with a single treatment plan and a long course of treatment. Long-term use of antibiotics has many side effects and is prone to drug resistance. Long-term use of drugs brings certain psychological pressure to patients, and the clinical efficacy is not ideal.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0064] When the dosage form of the medicine is a granule, its preparation method may comprise the following steps:

[0065] The first step is to mix the various raw materials of the drug according to the stated ratio, add ethanol with an alcohol concentration of 4 to 8 times that of the mixture, and heat it to boiling and reflux for 3 to 5 hours, filter, and use osmotic Slowly percolate at a speed of 1-2ml per minute by roller method, collect the percolation liquid, then concentrate under reduced pressure at a vacuum of 0.06-0.09Mpa to a paste with a relative density of 1.04-1.10 at 50-60°C, and spray dry , the air inlet temperature of the spray dryer is 160-175°C, the outlet air temperature is 80-85°C, and then crushed into powder to make dry paste powder;

[0066] In the second step, 0.2-0.4 times of sucrose powder and 0.1-0.2 times of dextrin are added to the obtained dry paste powder to form granules, and dried at 40-50° C. to obtain granules.

[0067] When the dosage for...

Embodiment 1

[0076] Example 1 Granules

[0077] The preparation process of the granules of the present invention is as follows: get plantain 100g, catch wind wood 220g, nutmeg 300g, Gentiana quinquefolium 150g, pair of leaves 350g, rotten maidservant 220g, mountain branch root 330g, barley dendrobium 200g, curcuma 150g, Radix Paeoniae Alba 300g, 140g rose flower, 200g ganoderma lucidum, 320g medlar leaves, 260g melon wood, 160g shixiantao, 300g thousand hammer, 230g stachyus glabra, 150g alkaline iris, 310g amaranth, 160g wormwood, 400g of thistle, 230g of kudzu, 170g of amomum, 140g of rose bud, 210g of fern and 300g of alfalfa;

[0078] The first step is to mix the raw materials of the pharmaceutical composition according to the stated ratio, add ethanol with an alcohol concentration of 90% that is 7 times that of the mixture, heat to boiling and reflux for 4 hours, filter, and use the percolation method at a rate of 90% per minute. Slowly percolate at a speed of 2ml, collect the percol...

Embodiment 2

[0080] Example 2 Capsules

[0081] The manufacture process of the capsule of the present invention is: get plantain 90g, catch wind chai 220g, nutmeg 300g, Gentiana 180g, pair of leaves 320g, rotten maid 200g, mountain twig root 330g, barley dendrobium 200g, curcuma 150g, Radix Paeoniae Alba 300g, 120g rose flower, 180g ganoderma lucidum, 330g medlar leaf, 250g melon wood, 170g Shixiantao, 150g thousand hammer, 210g stachyus glabra, 130g alkaline iris, 320g amaranth, 170g wormwood, 360g of thistle, 240g of kudzu, 170g of amomum, 150g of rose bud, 230g of fern and 300g of alfalfa;

[0082] The first step is to mix the raw materials of the pharmaceutical composition in proportion, add ethanol with an alcohol concentration of 90% that is twice the mass of the mixture, heat and reflux for 2 hours, extract, and filter to obtain the first extract; Then add ethanol with an alcohol concentration of 95% to the dregs of the dregs, heat and reflux for 2 hours, extract, and filter to obt...

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Abstract

The invention discloses a medicine for treating stomach-yin deficiency type peptic ulcer and a preparation method thereof. The medicine is prepared from the following medicinal materials including herba plantaginis, berchemia sinica, nakedflower beautyberry branchlet and leaves, myristica fragrans, gentiana macrophylla, alate pteracanthus leaves, Japanese premna stems or leaves, glabrousleaf pittosporum roots, Yunnan bulbophyllum herb, rhizoma zedoariae, radix paeoniae alba, rose blooms, glossy ganoderma, Chinese holly leaves, oldham fissistigma roots, conespike flemingia roots, daphne genkwa, long pepper, Chinese pholidota pseudobulb or herb, chun spicebush roots, marshy betony herb, Chinese iris seeds, gomphrena celosioides, denseflower bulbophyllum herb, denseflower blumea herb, Cirsium vlassovianum, oriental grape, fructus amomi, macartney rose, silverweed cinquefoil roots and medicago lupulina. The medicine has the beneficial effects that the efficacies of regulating the spleen and the stomach, strengthening the spleen, benefiting qi, reinforcing the stomach and nourishing yin are achieved; the effects of clearing away heat, removing dampness by dieresis, enhancing the appetite and relieving pain are also achieved; the medicine is mainly used for treating stomach-yin deficiency type peptic ulcer; the gastric mucosa can be protected; the damp heat constitution of a patient can be effectively relieved; the body immune function is integrally regulated; and the advantages of fast effect taking, high effective rate, exact curative effect, short treatment course, no toxic and side effects, low price and the like are realized.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical preparations, in particular to a medicine for treating gastric yin deficiency type peptic ulcer and a preparation method thereof. Background technique [0002] Peptic ulcer mainly refers to chronic ulcers that occur in the stomach and duodenum. It is a frequently-occurring disease and a common disease. There are various factors in the formation of ulcers, among which the digestion of mucous membrane by acidic gastric juice is the basic factor in the formation of ulcers, hence the name. Any part in contact with acidic gastric juice, such as the lower esophagus, the anastomotic port after gastrointestinal anastomosis, the jejunum, and Meckel's diverticulum with heterotopic gastric mucosa, the vast majority of ulcers occur in the duodenum and stomach, so they are also called stomach, ten duodenal ulcer. [0003] The etiology and pathogenesis of peptic ulcer in traditional Chinese medicine: T...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P1/04A61P37/02
CPCA61K36/9066A61K9/1652A61K9/19A61K9/4858A61K36/074A61K36/185A61K36/19A61K36/28A61K36/48A61K36/51A61K36/53A61K36/54A61K36/65A61K36/67A61K36/68A61K36/71A61K36/72A61K36/73A61K36/738A61K36/83A61K36/85A61K36/87A61K36/88A61K36/898A61K36/9064A61K47/10A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 李孝国
Owner YANTAI MINWANG ELECTROMECHANICAL TECH CO LTD
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