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Compound oral liquid for treating children diarrhea and preparation method thereof

A technology for infantile diarrhea and oral liquid, which is applied in the field of compound oral liquid for the treatment of infantile diarrhea and its preparation, can solve the problems of incomplete establishment of enzyme system, weak detoxification and detoxification function, and poor prognosis, so as to protect the gastrointestinal tract , promote absorption and utilization, and improve the body's immunity

Inactive Publication Date: 2016-09-07
钟志敏
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because the tissues and organs of children are in the stage of continuous development and maturity, in addition to being different from adults in body weight, there are also differences in physiology and pathology, especially in children, the liver, kidney and other organs are not fully developed, and the enzyme system is not fully established. Detoxification The function of detoxification is very weak. When using drugs, the absorption, distribution, metabolism and excretion in the body of children are significantly different from those of adults. It is very unscientific and harmful for children to take them after converting them into a fraction of the adult drugs. It is also common that severe constipation often occurs after children take medicine for antidiarrheal, resulting in poor prognosis, so it is extremely important to develop a special drug for children with diarrhea

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Embodiment 1: This embodiment prepares a compound oral liquid for treating diarrhea in children, which is composed of the following components by weight: 38 parts of Nutrilite Beilijian powder, 11 parts of dideoxyinosine, 9 parts of Gastrodia elata polypeptide, 2 parts of disaccharidase, 11 parts of ribavirin, 9 parts of racecadotril, 2 parts of bismuth pectin, 1 part of aluminum magnesium carbonate, 23 parts of dry yeast, 19 parts of probiotics, 5 parts of potassium chloride, chlorine 5 parts of sodium chloride, 1 part of sodium lactate, 1 part of calcium gluconate, 2 parts of flavoring agent, 0.4 part of emulsifier, 0.5 part of buffer, 0.01 part of antioxidant.

[0017] Wherein, the probiotics are mixed bacteria formed by mixing Bacillus licheniformis, Clostridium butyricum, Bacillus subtilis, and Enterococcus in a mass ratio of 2:3:5:6. The growth of physiological anaerobic bacteria can adjust the imbalance of intestinal flora, restore intestinal function, have speci...

Embodiment 2

[0023] Embodiment 2: This embodiment prepares a compound oral liquid for treating diarrhea in children, which is composed of the following components by weight: 47 parts of Nutrilite Beilijian powder, 17 parts of dideoxyinosine, 13 parts of Gastrodia elata polypeptide, 4.5 parts of disaccharidase, 16.5 parts of ribavirin, 11 parts of racecadotril, 3.5 parts of bismuth pectin, 1.5 parts of aluminum magnesium carbonate, 33 parts of dry yeast, 23.5 parts of probiotics, 8 parts of potassium chloride, chlorine 8 parts of sodium chloride, 2.5 parts of sodium lactate, 2.5 parts of calcium gluconate, 3 parts of flavoring agent, 0.5 part of emulsifier, 0.7 part of buffer, 0.025 part of antioxidant.

[0024] Wherein, the probiotics are mixed bacteria formed by mixing Bacillus licheniformis, Clostridium butyricum, Bacillus subtilis, and Enterococcus in a mass ratio of 2:3:5:6. The growth of physiological anaerobic bacteria can adjust the imbalance of intestinal flora, restore intestinal ...

Embodiment 3

[0030] Example 3: This example prepares a compound oral liquid for treating diarrhea in children, which is composed of the following components by weight: 56 parts of Nutrilite Beilijian powder, 23 parts of dideoxyinosine, 17 parts of Gastrodia elata polypeptide, 7 parts of disaccharidase, 22 parts of ribavirin, 13 parts of racecadotril, 5 parts of bismuth pectin, 2 parts of aluminum magnesium carbonate, 43 parts of dry yeast, 28 parts of probiotics, 11 parts of potassium chloride, chlorine 11 parts of sodium chloride, 4 parts of sodium lactate, 4 parts of calcium gluconate, 4 parts of flavoring agent, 0.6 part of emulsifier, 0.9 part of buffer, 0.04 part of antioxidant.

[0031] Wherein, the probiotics are mixed bacteria formed by mixing Bacillus licheniformis, Clostridium butyricum, Bacillus subtilis, and Enterococcus in a mass ratio of 2:3:5:6. The growth of physiological anaerobic bacteria can adjust the imbalance of intestinal flora, restore intestinal function, have spec...

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Abstract

The invention discloses a compound oral liquid for treating children diarrhea and a preparation method thereof. The compound oral liquid for treating the children diarrhea comprises the following components of Nutrilite Double powder, dideoxyinosine, gastrodia elata polypeptide, disaccharidase, ribavirin, racecadotril, bismuth pectin, hydrotalcite, dry yeast, probiotics, potassium chloride, sodium chloride, sodium lactate, calcium gluconate, corrigent, emulsifying agent, buffer liquid, and antioxidant. The compound oral liquid for treating the children diarrhea has the advantages that the environment of children gastrointestinal tracts is improved, the effective microbial community is increased, the digestion and adsorbing of gastrointestinal tract are promoted, the water-electrolyte metabolic disorder is prevented, and the body immunity is improved; the cost is low, the toxic or side effect is little, the compound oral liquid can be used for a long time, and the children diarrhea can be prevented and thoroughly cured after long-time administration.

Description

technical field [0001] The invention relates to the technical field of pediatric medication, in particular to a compound oral liquid for treating infantile diarrhea and a preparation method thereof. Background technique [0002] Diarrhea in children refers to a frequently-occurring disease in children with changes in stool properties and more frequent stools than usual before the cause is not identified. Diarrhea is a group of diseases caused by multiple causes and factors, and is the disease with the highest incidence in childhood One of them is a worldwide public health problem. Diarrhea occurs in at least 1 billion people around the world every year. According to the World Health Organization survey, about 10,000 people die from diarrhea every day. In my country, diarrheal disease is also a common disease in children. According to relevant data, the annual incidence rate of diarrheal disease in children under 5 years old in my country is 201%, with an average of 3.5 cases...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K45/06A61K38/47A61K38/54A61K47/40A61K9/08A61P1/12A61K31/19A61K31/191A61K31/265A61K31/7056A61K31/708A61K33/10A61K33/14A61K33/24A61K35/741
CPCA61K45/06A61K9/0095A61K31/19A61K31/191A61K31/265A61K31/7056A61K31/708A61K33/10A61K33/14A61K33/245A61K35/741A61K36/064A61K36/8988A61K38/47A61K38/54A61K47/40
Inventor 钟志敏
Owner 钟志敏
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