Pharmaceutical composition for curing cervicitis and preparation method and application of pharmaceutical composition

The technology of a composition and a pharmaceutical preparation is applied in the field of pharmaceutical compositions for the treatment of cervicitis and the preparation thereof, can solve the problems of temperature intolerance, the anti-inflammatory effect cannot meet actual requirements and the like, achieves avoiding damage, reducing working steps, The effect of increasing the content of active ingredients

Active Publication Date: 2016-10-12
JIANGSU KANION PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The inventor found through research that the anti-inflammatory effect of the composition disclosed in CN101919991B cannot meet the actual requirements due to the compatibility of the formula and the preparation process. The active ingredient chlorogenic acid is intolerant to temperature, etc.

Method used

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  • Pharmaceutical composition for curing cervicitis and preparation method and application of pharmaceutical composition
  • Pharmaceutical composition for curing cervicitis and preparation method and application of pharmaceutical composition
  • Pharmaceutical composition for curing cervicitis and preparation method and application of pharmaceutical composition

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] Embodiment 1 suppository preparation embodiment

[0046] The present embodiment raw material medicine consists of:

[0047] Honeysuckle 3.428kg (about 13.8 parts by weight) Forsythia 3.428kg (about 13.8 parts by weight) Phellodendron 3.428kg (about 13.8 parts by weight) Comfrey 3.428kg (about 13.8 parts by weight) Curcuma 6.856kg (about 27.6 parts by weight) Centipede 1.028kg (about 4.2 parts by weight) white and 1.2kg (about 4.8 parts by weight) gallnut 2kg (about 8.1 parts by weight).

[0048] The bulk drug of above-mentioned weight is made the suppository of described pharmaceutical composition through following steps:

[0049] Take zedoary and add 8 times the weight of water, soak overnight, extract volatile oil for 8 hours to obtain zedoary oil, filter the medicinal liquid after extracting volatile oil to obtain extract a;

[0050] After mixing Cortex Cortex Phellodendri, Honeysuckle and Comfrey, add 8 weight times of ethanol with a volume fraction of 70%, reflux...

Embodiment 2

[0054] Embodiment 2 suppository preparation embodiment

[0055] The present embodiment raw material medicine consists of:

[0056] Honeysuckle 2.484kg (10 parts by weight), Forsythia 1.244kg (5 parts by weight), Phellodendron 1.244kg (5 parts by weight), Comfrey 2.484kg (10 parts by weight), Curcuma 4.968kg (20 parts by weight), centipede 1.244kg (5 parts by weight), white and 1.244kg (5 parts by weight), gallnut 1.244kg (5 parts by weight).

[0057] The bulk drug of above-mentioned weight is made the suppository of described pharmaceutical composition through following steps:

[0058] Take zedoary and add 5 times the weight of water, soak overnight, extract volatile oil for 10 hours to obtain zedoary oil, filter the medicinal liquid after extracting volatile oil to obtain extract a;

[0059] After mixing Cortex Cortex Phellodendri, honeysuckle and comfrey, add 5 times by weight of ethanol with a volume fraction of 50%, reflux extraction for 3 times, each time for 2 hours, c...

Embodiment 3

[0063] Embodiment 3 effervescent agent preparation embodiment

[0064] The present embodiment raw material medicine consists of:

[0065] Honeysuckle 3.728kg (15 parts by weight), Forsythia 3.728kg (15 parts by weight), Phellodendron 3.728kg (15 parts by weight), Comfrey 3.728kg (15 parts by weight), Curcuma 7.452kg (30 parts by weight), centipede 1.244kg (5 parts by weight), white and 1.244kg (5 parts by weight), gallnut 2.484kg (10 parts by weight).

[0066] The crude drug of above-mentioned weight is made the effervescent agent of described pharmaceutical composition through following steps:

[0067] Take zedoary and add 8 times the weight of water, soak overnight, extract volatile oil for 8 hours to obtain zedoary oil, filter the medicinal liquid after extracting volatile oil to obtain extract a;

[0068] After mixing Cortex Cortex Phellodendri, Honeysuckle and Comfrey, add 8 weight times of ethanol with a volume fraction of 70%, reflux extraction twice, each time for 1....

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Abstract

The invention relates to pharmaceutical composition for curing cervicitis and a preparation method and application of the pharmaceutical composition. The pharmaceutical composition comprises zedoary turmeric oil, fine powder and pharmaceutically acceptable auxiliary materials. The zedoary turmeric oil and the fine powder are prepared from the following raw medical materials of honeysuckle flower, fructus forsythiae, cortex phellodendri, radix arnebiae seu lithospermi, rhizoma curcumae, scolopendra, rhizoma bletillae and Chinese gall according to following steps. The steps comprise extracting oil of the rhizoma curcumae to obtain volatile oil and an extracting solution a and combining the extracting solution a with an aqueous alcohol extracting solution b of the cortex phellodendri, the honeysuckle flower and the radix arnebiae seu lithospermi and an aqueous extracting solution c of the scolopendra, the fructus forsythiae, the Chinese gall and the rhizoma bletillae. Experiments show that the pharmaceutical composition has a good curative effect on cervical erosion and a good anti-inflammatory effect.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating inflammation and its preparation method and application, in particular to a pharmaceutical composition for treating cervicitis and its preparation method and application. Background technique [0002] Cervicitis is a common gynecological disease. Symptoms include increased leucorrhea, waist and abdomen pain, lumbosacral discomfort, or irregular menstruation. If you do not pay attention, pathogens such as streptococcus, staphylococcus, E. coli, mold, and trichomonas It can invade any part of the cervix and cause inflammation by spreading upward along the genital mucosa, spreading through blood, spreading through lymphatics, and spreading directly. The main manifestations of cervicitis are cervical erosion, cervical mucosal polyps, cervical hypertrophy and cervical gland cysts, etc., which can exist at the same time, or both or alone. Cervical erosion is mainly formed in the following wa...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P15/00A61K35/648A61K35/64
CPCA61K35/63A61K35/648A61K36/30A61K36/355A61K36/634A61K36/756A61K36/898A61K36/9066A61K2236/331A61K2236/333A61K2300/00
Inventor 萧伟殷洪梅吴云徐忠坤李峰康小东孙永城丁岗王振中
Owner JIANGSU KANION PHARMA CO LTD
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