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Preparation method of radix salviae miltiorrhizae cellwall-broken decoction piece

A technology of broken wall decoction pieces and purple salvia miltiorrhiza, applied in the field of preparation of broken wall decoction pieces of purple salvia miltiorrhiza, can solve problems such as no treatment method provided for microbial limit, rapid dissolution of unfavorable medicinal active ingredients, unsuitable medicinal materials, etc., to ensure drug safety and drug safety Effect, moderate elasticity, easy to dry effect

Inactive Publication Date: 2016-10-26
湖南盟合投资管理有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] According to the current technology, the granules of the broken wall decoction pieces of purple salvia miltiorrhiza are not only fastened, but also small, which is difficult to dissolve in the actual use process, which is not conducive to the rapid dissolution of the effective ingredients; the medicinal materials can only be selected and sliced. Specially processed medicinal materials are not applicable; there is no treatment method for whether the coarse powder entering the clean area meets the microbial limit

Method used

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  • Preparation method of radix salviae miltiorrhizae cellwall-broken decoction piece

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Experimental program
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Effect test

Embodiment 1

[0037] Purple Danshen Broken Wall Decoction Pieces

[0038] 1) Medicinal material treatment: pick and clean / process the purple salvia miltiorrhiza medicinal material, dry the medicinal material until the water content of the medicinal material is below 10%, and crush the medicinal material into small particles of about 10 mesh with a 10-mesh sieve; further coarse crush The medicinal materials reach about 100 mesh;

[0039] 2) Intermittent sterilization: Put the coarse powder of red salvia miltiorrhiza in a constant temperature and humidity box with a thickness of about 10mm, set the temperature at 65°C (the actual temperature is 60-70°C), and keep it dry and sterilized for 8 hours; the coarse powder of the treated medicinal material Maintain at a temperature of 25°C and a relative humidity of 75% for 12 hours; then adjust the temperature of the constant temperature and humidity box to 35°C and maintain a relative humidity of 88% for 24 hours; change the set temperature to 75°C...

Embodiment 2

[0045] Purple Danshen Broken Wall Decoction Pieces

[0046] 1) Medicinal material treatment: the purple salvia miltiorrhiza medicinal material is sorted, cleaned / processed, and dried until the water content of the medicinal material is below 10%, and the medicinal material is crushed into small particles of about 10 mesh by a mechanical crusher with a 10-mesh screen; the medicinal material is further coarsely crushed Reach about 100 mesh;

[0047] 2) Intermittent sterilization: Put the coarse powder of red salvia miltiorrhiza in a constant temperature and humidity box with a thickness of about 5mm, set the temperature at 70°C (the actual temperature is 65-75°C), and keep it dry and sterilized for 4 hours; the coarse powder of the treated medicinal material Maintain at a temperature of 20°C and a relative humidity of 70% for 15 hours; then adjust the temperature of the constant temperature and humidity box to 33°C and maintain a relative humidity of 83% for 8 hours; change the ...

Embodiment 3

[0053] Purple Danshen Broken Wall Decoction Pieces

[0054] 1) Medicinal material treatment: the purple salvia miltiorrhiza medicinal material is sorted, cleaned / processed, and dried until the water content of the medicinal material is below 10%, and the medicinal material is crushed into small particles of about 10 mesh by a mechanical crusher with a 10-mesh screen; the medicinal material is further coarsely crushed Reach about 100 mesh;

[0055] 2) Intermittent sterilization: Put the coarse powder of red salvia miltiorrhiza in a constant temperature and humidity box with a thickness of about 30mm, set the temperature at 75°C (the actual temperature is 70-80°C), and keep it dry and sterilized for 4 hours; the coarse powder of the treated medicinal material Maintain at a temperature of 25°C and a relative humidity of 75% for 24 hours; then adjust the temperature of the constant temperature and humidity box to 40°C and maintain a relative humidity of 80% for 12 hours; place the...

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Abstract

The invention provides a preparation method of a radix salviae miltiorrhizae cellwall-broken decoction piece. The preparation method comprises the following steps: picking and choosing medicinal materials and cleaning / processing, drying, breaking, crushing by a pulverizer with 100-mesh sieve, carrying out batch-type sterilization, breaking cell walls, pelletizing, and drying to prepare the radix salviae miltiorrhizae cellwall-broken decoction piece. The prepared decoction piece has good grain shape and moderate degree of tightness. In addition, the prepared granules are easy to dry, is rapid to dissolve and disperse, and is easy to disperse when being taken by a user. The batch-type sterilization meets the requirement of microbial limit. The problem that radix salviae miltiorrhizae cellwall-broken decoction pieces on the current market are hard to dissolve and disperse and microbial limit is difficult to reach the standard is solved.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine treatment, in particular to a preparation method of broken-wall decoction pieces of purple salvia miltiorrhiza. Background technique [0002] Ultrafine pulverization technology is a new technology developed rapidly in recent years. Most of the active ingredients in Chinese herbal medicines are distributed in the cells. When decocting conventional decoction pieces, only part of the active ingredients can be released. About 86.7% of the cell wall breaking rate will improve the dissolution of the active ingredients in the medicinal materials, greatly enhance its efficacy, and the utilization rate of the active ingredients will be above 90%, so as to reduce the amount of medicinal materials used and protect the medicinal materials resources. The quality increases the efficacy. Purple Salvia, also known as Danshen, red ginseng, mountain ginseng, galloping horse grass, blood ginse...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/537A61K9/16
CPCA61K36/537A61K9/16A61K2236/10A61K2236/13A61K2236/15A61K2236/17
Inventor 朱瑞清杨记宗罗林波关建雄邱光升
Owner 湖南盟合投资管理有限公司
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