This invention discloses a compound
traditional Chinese medicine powder inhaler for
respiratory tract infections and its preparation method, relating to the field of
pharmaceutical formulation technology. The compound
traditional Chinese medicine powder inhaler for
respiratory tract infections is composed of
polysaccharide composite gel microspheres,
forsythia,
scutellaria,
honeysuckle, and
isatis root. The
polysaccharide composite gel microspheres are composed of seaweed sulfated
polysaccharide,
lentinan,
calcium chloride, and
curcumin. Seaweed sulfated polysaccharide,
lentinan,
curcumin, and
calcium chloride cross-link to form a three-dimensional network spherical structure, improving the particle morphology and flowability of the micropowder. Furthermore, due to its good hygroscopic and moisturizing properties, it competitively reduces the
moisture absorption of the micropowder, preventing aggregation and further improving flowability. In addition, the gel microspheres have excellent adhesion, adhering to the infection site after entering the
respiratory tract, reducing expulsion losses due to
respiration, maintaining an
effective drug concentration at the infection site, and improving therapeutic
efficacy.