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Sanmiao capsule and method for preparing same

A capsule and Sanmiao technology, applied in the field of traditional Chinese medicine, can solve the problems of long disintegration time of pills, slow digestion and absorption, improper operation, etc., and achieve the effects of shortening disintegration time and onset time, increasing content and increasing action strength

Inactive Publication Date: 2016-11-09
JIANGSU 707 NATURAL PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The 2015 edition of "Chinese Pharmacopoeia" records the Shuifan pills made of Sanmiao pills as the original powder. The pills take a long time to disintegrate and take a large amount. Moreover, the active ingredients of the medicine are not extracted and exist in the original plant cells. , slow digestion and absorption, improper operation, microorganisms are easy to exceed the standard

Method used

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  • Sanmiao capsule and method for preparing same
  • Sanmiao capsule and method for preparing same
  • Sanmiao capsule and method for preparing same

Examples

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Effect test

Embodiment 1

[0017] A kind of Sanmiao capsule, is made of the following components by weight: 4 parts of Rhizoma Atractylodis, 2 parts of Cortex Phellodendri, 1 part of Achyranthes bidentata, the average volatile oil total amount of described Sanmiao capsule is 2.21%, and the average disintegration time is less than After 15 minutes, the content of berberine hydrochloride was 3.4mg / g.

[0018] The preparation method of described San Miao capsule, comprises the following steps:

[0019] (1) Atractylodes atractylodis and Cortex Phellodendri are percolated with 70% ethanol solution as solvent, and ethanol is recovered from the percolation solution, which is collected in another device for later use;

[0020] (2) Add water to decoct the herb dregs and Achyranthes bidentata after infiltration of Atractylodes atractylodes and Cortex Phellodendri for two times. The amount of water added is 6 times the amount of medicinal materials for the first time, and 4 times the amount of medicinal materials ...

Embodiment 2

[0023] A kind of Sanmiao capsule, is made of the following components by weight: 5 parts of Rhizoma Atractylodis, 3 parts of Cortex Phellodendri, 2 parts of Achyranthes Radix, the average volatile oil total amount of described Sanmiao capsule is 1.93%, and average disintegration time is less than After 15 minutes, the content of berberine hydrochloride was 3.5 mg / g.

[0024] The preparation method of described San Miao capsule, comprises the following steps:

[0025] (1) Atractylodes atractylodis and Cortex Phellodendri are percolated with 90% ethanol solution as solvent, and the ethanol is recovered from the percolation solution, which is collected in another device for later use;

[0026] (2) Add water to decoct the herb dregs and Achyranthes bidentata after infiltration of Atractylodes atractylodes and Phellodendron Phellodendron for two times, the amount of water added is 8 times the amount of medicinal materials for the first time, and 6 times the amount of medicinal mate...

Embodiment 3

[0029] A kind of Sanmiao capsule, is made of following components by weight: 6 parts of Rhizoma Atractylodis, 2 parts of Cortex Phellodendri, 2 parts of Achyranthes bidentata, the average volatile oil total amount of described Sanmiao capsule is 2.34%, and average disintegration time is less than After 15 minutes, the content of berberine hydrochloride was 3.8mg / g.

[0030] The preparation method of described San Miao capsule, comprises the following steps:

[0031] (1) Atractylodes atractylodis and Phellodendron Phellodendri are percolated with 85% ethanol solution as solvent, and after ethanol is recovered from the percolation liquid, it is collected in another device and set aside;

[0032] (2) Add water to decoct the herb dregs and Achyranthes bidentata after infiltration of Atractylodes atractylodes and Phellodendron Phellodendron for two times. The amount of water added is 7 times the amount of medicinal materials for the first time, and 5 times the amount of medicinal m...

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Abstract

The invention discloses a Sanmiao capsule and a method for preparing the same. The Sanmiao capsule comprises, by weight, 3-6 parts of rhizoma atractylodis, 2-3 parts of cortex phellodendri and 1-2 parts of radix achyranthis bidentatae. The total quantity of average volatile oil in the Sanmiao capsule is 1.8%-2.5%, the average disintegration time of the Sanmiao capsule is shorter than 15 min, and the content of berberine hydrochloride in the Sanmiao capsule is 3.4 mg / g-3.8 mg / g. The method includes percolating and extracting the rhizoma atractylodis and the cortex phellodendri by the aid of ethyl alcohol solution; decocting percolated herb residues and the radix achyranthis bidentatae in water; combining percolation liquid and decoction with each other to obtain mixed liquid; concentrating the mixed liquid under vacuum conditions and drying the mixed liquid to obtain the Sanmiao capsule. The Sanmiao capsule and the method have the advantages that processes for preparing the Sanmiao capsule are improved, the contents of efficacy components in medicines can be increased, the disintegration time and the onset time can be shortened, the action strength can be improved, and the Sanmiao capsule can be used for treating diseases such as erysipelas on lower limbs due to dampness-heat, chronic prostatitis and gout.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a Sanmiao capsule and a preparation method thereof. Background technique [0002] Sanmiao Pills originated from the "Medical True Story" of the Ming Dynasty. It is composed of Cangzhu (stir-fried), Phellodendron Phellodendri (fried) and Achyranthes bidentata. It has the function of drying dampness and clearing away heat. It is used for betting on damp heat. The symptoms include redness, swelling and heat pain in the feet and knees, heaviness in the lower limbs, and less yellow urine. Phellodendron Phellodendri in the prescription is the main drug, which clears away heat and dampness, and is good at lower energies to cure dampness and heat in the lower energies; Atractylodes atractylodes is used as an auxiliary drug to dry dampness and invigorate the spleen, and can sweat and pass through the meridians; , leading herb and Cortex Phellodendron into...

Claims

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Application Information

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IPC IPC(8): A61K36/756A61K9/48A61P13/08A61P19/06A61P17/02A61P31/04
CPCA61K36/756A61K9/48A61K36/21A61K36/284A61K2236/331A61K2236/333A61K2236/39
Inventor 窦宪陈晓芳
Owner JIANGSU 707 NATURAL PHARMA
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