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Yishenjuanbi pills and preparation method thereof

A technology of Yishen Juanbi Pills and Drynariae, applied in the directions of pill delivery, pharmaceutical formulations, and medical preparations containing active ingredients, can solve the problems of slowing down the process of joint structure destruction, easy recurrence, and large trauma, etc. Achieving good application prospects, enhancing drug efficacy, and reducing damage

Inactive Publication Date: 2016-11-16
上海典实医疗科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

So far, no specific drug has been found that can prevent or significantly slow down the process of joint structural destruction
As for surgical treatment, due to very strict indication requirements, less than 5% of the population suitable for surgery is clinically suitable, and there are characteristics such as high cost, large trauma, long recovery period, and easy recurrence, so it is impossible to fully promote this rheumatoid arthritis at all. treatment

Method used

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  • Yishenjuanbi pills and preparation method thereof
  • Yishenjuanbi pills and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] A preparation method of Yishen Juanbi Pills, comprising the following steps:

[0047] (1) Weigh 15 parts of Rhizoma Drynariae, 15 parts of Guangdilong, 25 parts of Geranium, 15 parts of Epimedium, 25 parts of Caulis Spatholobus, 25 parts of Polygonum cuspidatum, 30 parts of Rehmannia, 25 parts of Humulus, Angelica 15 parts, 15 parts of Xu Changqing, 25 parts of Rehmannia glutinosa, 15 parts of Corydalis Corydalis, 15 parts of Lumigrass, crushed into 60-mesh coarse powder, sieved, mixed evenly, and carried out supercritical carbon dioxide extraction, extraction time 80-150 minutes, extraction temperature 48°C, extraction pressure 30MPa, add 30% entrainer of medicinal material weight during the extraction process, the flow rate of carbon dioxide is 15kg / h, obtain the extracted medicinal liquid, filter, filter residue for later use, and concentrate the filtrate under reduced pressure to a density of 1.20 (50°C) extract clear paste;

[0048] (2) Add 10 times the amount of ...

Embodiment 2

[0055] It is basically the same as Example 1, except that the auxiliary material is obtained by uniformly mixing baicalein and hyperin at a mass ratio of 1:1. Obtain the Yishen Juanbi pill of embodiment 2.

Embodiment 3

[0057] It is basically the same as Example 1, except that the auxiliary material is obtained by uniformly mixing baicalein and soybean isoflavone at a mass ratio of 1:1. Obtain the Yishen Juanbi pill of embodiment 3.

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PUM

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Abstract

The invention discloses Yishenjuanbi pills and a preparation method thereof. The Yishenjuanbi pills are prepared from raw materials in parts by weight as follows: fortune's drynaria rhizomes, prepared rehmannia roots, Chinese angelica, paniculate swallowwort roots, ground beetles, stiff silkworms, centipedes, scorpions, honeycombs, earthworms, black-striped snakes, corydalis yanhusuo, pyrola herbs, epimedium herbs, Carolina Cranesbill herbs, suberect spatholobus stems, humulus japonicus, dried rehmannia roots and giant knotweed rhizomes. Oil-soluble and water-soluble active ingredients can be fully extracted, damage to the active components can be reduced, efficacy can be enhanced, and the Yishenjuanbi pills are more suitable for being used as a drug for treating rheumatic arthritis and have quite good application prospect.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a Yishen Juanbi pill and a preparation method thereof. Background technique [0002] Rheumatoid arthritis is a common acute or chronic inflammation of connective tissue. Can be recurrent and involve the heart. Clinically, it is characterized by migratory soreness, weight, and pain in joints and muscles. An allergic disease. It is one of the main manifestations of rheumatic fever, mostly with acute fever and arthralgia onset. Typical manifestations are mild or moderate fever and migratory polyarthritis. The affected joints are mostly large joints such as knees, ankles, shoulders, elbows, and wrists. It is common to transfer from one joint to another, and the lesion is locally red and swollen. , scorching heat, severe pain, and some patients also have several joints falling ill at the same time. Atypical patients only have joint pain without o...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/804A61K9/20A61P19/02A61P29/00A61K35/583A61K35/62A61K35/64A61K35/646A61K35/648
CPCA61K9/2013A61K9/2018A61K35/583A61K35/62A61K35/63A61K35/646A61K35/648A61K36/126A61K36/185A61K36/232A61K36/27A61K36/296A61K36/486A61K36/60A61K36/66A61K36/704A61K36/804A61K2236/331A61K2236/51A61K2236/37A61K2236/39A61K2300/00
Inventor 陆敏佳
Owner 上海典实医疗科技有限公司