Condensed pill for treating chronic pharyngitis and preparation method of condensed pill

A technology for chronic pharyngitis and concentrated pills, which is applied in the direction of medical preparations containing active ingredients, pill delivery, sugar-coated pills, etc. It can solve the problems of different formulas and preparation methods, achieve good therapeutic effects, and the preparation process is simple and easy to implement Effect

Inactive Publication Date: 2016-11-23
成都黄再军医院有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] After searching, there are few relevant reports on pills for the treatment of chronic pharyngitis at present, and the formulas and preparation methods used are different, such as "Preparation and Clinical Application of Runhou Liyan Pills", "Preparation and Clinical Application of Xiashenyanning Pills" " and " Preparation and Clinical Application of Yanyanling Pills"

Method used

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  • Condensed pill for treating chronic pharyngitis and preparation method of condensed pill
  • Condensed pill for treating chronic pharyngitis and preparation method of condensed pill
  • Condensed pill for treating chronic pharyngitis and preparation method of condensed pill

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] prescription

[0029] Scutellaria baicalensis 15g, Nansha ginseng 16g, Scrophulariaceae 16g, Lily 16g, winter mulberry leaves 12g, loquat leaves 12g, salvia miltiorrhiza 12g, brocade lantern 15g, green fruit 7g, schisandra 7g, green calyx plum 7g, tangerine 7g, loofah 7g, Raw licorice 7g

[0030] Note: expand the above prescription by 30 times (4680g) for production:

[0031] Scutellaria baicalensis 450g, Nansha ginseng 480g, Scrophulariaceae scrophulariae 480g, Lily 480g, Winter mulberry leaves 360g, Loquat leaves 360g, Salvia miltiorrhiza 360g, Brocade lantern 450g, Green fruit 210g, Schisandra 210g, Green calyx plum 210g, Tangerine 210g, Loofah 210g , raw licorice 210g

[0032] Made into 1000g

[0033] Lilium 0.48kg, green calyx plum 0.21kg are pulverized into the fine powder of crossing 100 mesh sieves, receiving 0.62kg (receiving rate 90%), for subsequent use;

[0034] Put 3.99kg of 12 kinds of medicinal materials such as Scutellaria baicalensis into the heat r...

Embodiment 2

[0062] Pilot test (175 times the original prescription for production, 27.3kg in total)

[0063] Prescription and Preparation

[0064] Scutellaria baicalensis 2.63kg, Nansha ginseng 2.8kg, Scrophularia ginseng 2.8kg, Lily 2.8kg, winter mulberry leaves 2.1kg, roasted loquat leaves 2.1kg, salvia miltiorrhiza 2.1kg, brocade lantern 2.63kg, green fruit 1.23kg, schisandra 1.23kg, green calyx plum 1.23kg kg, orange 1.23kg, loofah 1.23kg, raw licorice 1.23kg

[0065] Made into 5000g

[0066] Take 2.8kg of lily and 1.2kg of green calyx plum and grind them into fine powder (through a 100-mesh sieve) for the above fourteen herbs, and set aside; add the other twelve herbs, such as Scutellaria baicalensis, into a hot reflux extraction and concentrator, add water and soak for 30 minutes Extract and concentrate. Extract for 90 minutes (after boiling), pump the filtrate into the concentration tank and concentrate to a clear ointment with a relative density of 1.2-1.25 (60°C); mix the abov...

experiment example 1

[0090] Determination of extraction time and times:

[0091] 3990g of 12 kinds of medicinal materials such as Scutellaria baicalensis except lily and green plum, add 31.L of water for the first time, decoct for 90 minutes; add 24L of water for the second time (6 times the amount of medicinal materials), decoct for 60 minutes, according to The weight of the decoction (extract) determines the extraction time and number of times, and the results are shown in Table 1 through the test.

[0092] Table 1 The decoction times and comparative test results of Scutellaria baicalensis and other medicinal materials

[0093]

[0094] the result shows:

[0095] According to the above experimental analysis, adding 31L of water, the first extraction yielded 13% in 60 minutes, which did not reach the desired effect; 90 minutes of extraction yielded 18%, and achieved the expected effect, and the active ingredients were basically extracted completely. Add water 24L for the second extraction Fo...

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Abstract

The invention provides a condensed pill for treating chronic pharyngitis and a preparation method of the condensed pill. The preparation method includes selecting, by weight, 15 parts of scutellaria baicalensis, 16 parts of adenophora tetraphylla, 16 parts of radix scrophulariae, 16 parts of lilies, 12 parts of morus alba, 12 parts of fried loquat leaves, 12 parts of the root of red-rooted salvia, 15 parts of physali alkekengi, 7 parts of terminalia chebula, 7 parts of schisandra chinensis, 7 parts of armeniaca mume, 7 parts of orange fibers, 7 parts of loofah sponge and 7 parts of licorice roots as raw materials, and controlling extraction, concentration and coating processes to obtain the condensed pill. The condensed pill has good curative effect, is convenient to take and can disintegrate, dissolve and be absorbed quickly after being taken, and effective components can be fully utilized. The preparation process is simple, easy to implement and low in cost, and chronic patients, who need to take the pill for a long time, can be truly benefited from the price.

Description

technical field [0001] The invention belongs to the field of pharmaceutical engineering, and in particular relates to a concentrated pill for treating chronic pharyngitis and a preparation method thereof. Background technique [0002] Traditional Chinese medicine is generally a decoction, which is not only inconvenient to carry but also has a poor taste. It is a common practice to make traditional Chinese medicine formulas into easy-to-carry and take dosage forms, such as pills and capsules. However, due to the complex composition of traditional Chinese medicine, how to choose a preparation process suitable for the characteristics of raw materials and how to ensure that the curative effect is not affected are the main problems in the preparation work. For traditional Chinese medicine formulas with many raw material components, the above problems appear to be particularly important. [0003] After searching, there are few relevant reports on pills for the treatment of chron...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8967A61K9/28A61P11/04
CPCA61K9/2059A61K9/2806A61K36/185A61K36/342A61K36/42A61K36/484A61K36/537A61K36/539A61K36/57A61K36/605A61K36/73A61K36/736A61K36/752A61K36/79A61K36/808A61K36/81A61K36/8967A61K2236/331A61K2236/51A61K2300/00
Inventor 黄再军
Owner 成都黄再军医院有限责任公司
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