Traditional Chinese medicine composition used for treating amygdalitis, and preparation method thereof
A technology of tonsillitis and composition, applied in the direction of drug combination, medical formula, drug delivery, etc., can solve the problems of liver and kidney organ damage, side effects, unsuitable for long-term use, etc., and achieve rapid and effective treatment without toxic and side effects
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Embodiment 1
[0033] (1) A Chinese medicine for the treatment of tonsillitis, which is made up of the following raw materials in parts by weight:
[0034] 30 parts of Flat Bamboo Orchid, 25 parts of Garcinia Cambogia, 20 parts of White Orchid, 15 parts of Andrographis paniculata, 15 parts of Black Noodle Leaf, 10 parts of Pteris cactus, 10 parts of Asplenium spp., 10 parts of Licorice, 10 parts of Radix Isatidis, Duck Tongue 5 parts of grass and 5 parts of astragalus.
[0035] (2) Preparation method:
[0036] In the first step, Garcinia Cambogia and Bailanhua are mixed in proportion, and extracted twice with n-propanol with an alcohol concentration of 70% equivalent to twice the mass of the mixture. The filtrate is combined, concentrated under reduced pressure, dried and pulverized into powder. Ethanol is purified 1-2 times, the extracts are combined, the ethanol is recovered under reduced pressure and concentrated to a paste with a relative density of 1.21-1.24 at 60°C, dried and crushed into po...
Embodiment 2
[0041] (1) A Chinese medicine for the treatment of tonsillitis, which is made up of the following raw materials in parts by weight: the same as in Example 1.
[0042] (2) Preparation method:
[0043] In the first step, Garcinia Cambogia and Bailanhua are mixed in proportion, and extracted twice with n-propanol with an alcohol concentration of 70% equivalent to twice the mass of the mixture. The filtrate is combined, concentrated under reduced pressure, dried and pulverized into powder. Ethanol is purified once, the extracts are combined, the ethanol is recovered under reduced pressure and concentrated to a paste with a relative density of 1.21-1.24 at 60°C, dried and crushed into powder;
[0044] In the second step, the Andrographis paniculata, Black-faced leaves, Pteris cactus, and Asplenium spp. are extracted twice with n-propanol with an alcohol concentration of 80%. The extracts are combined, concentrated under reduced pressure, dried, and crushed into powder. The latter powder ...
Embodiment 3
[0048] 1. Long-term toxicity test process:
[0049] Using Wistar rats (provided by Beijing Weitong Lihua Laboratory Animal Technology Co., Ltd.), the experimental drugs were set to three doses of high, medium and low, respectively, 8g / kg, 4g / kg, and 2g of the capsules of the formula of Example 1 / kg. Calculated at a human dose of 0.1g / kg / day tablets, which are respectively 80 times, 40 times and 20 times the effective dose for humans; a control group was set up for continuous intragastric administration for 90 days, 180 days and partial animal withdrawal 10 After days, observe the effects on various physiological and biochemical indexes of rats. The results of the experiment showed that different doses were given to rats by oral administration for 180 days without any influence on the rats' food intake and weight gain. No obvious toxic effects on liver and kidney function were found. There was no significant effect on blood routine, blood biochemistry, urine biochemistry and b...
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