Novel series-parallel mass spectrometry device system and its parameter adjustment method and usage method

Abstract

The invention provides a novel series-parallel connection mass spectrum device system. The system comprises mass spectrum necessary basic subsystems, such as a set of quadrupole mass filter system, a special quadrupole rod / linear ion trap mass analyzer system, an ion guidance system, a quadrupole deflector, a hyperbolic quadrupole rod mass analyzer and ion counter system, a low air pressure linear ion trap mass spectrometer and electron multiplier system, a flight time mass spectrum system, a multi-path gas flow control system, a vacuum gauge, a multi-section differential motion vacuum system and the like. Furthermore, the invention provides a method for operating above systems to perform quantitative analysis in a triplet quadrupole rod mode, qualitative analysis in a quadrupole filtering medium combined high / low air pressure ion trap mode, and quick / high-mass precision analysis in a quadrupole filtering combined flight time mass spectrum mode on ultra-trace materials in a complex matrix, a method for utilizing an effective combination of three different mass analyzers to achieve optimal ion optical parameter adjustment and a method for performing high-precision qualitative and quantitative analysis on the ultra-trace materials.

Description

technical field [0001] The invention relates to a series-parallel quadrupole mass spectrometry device system, in particular to a series-parallel quadrupole mass spectrometer system that realizes qualitative analysis and quantitative analysis for ultra-trace substances in different modes on the same device. Background technique [0002] The method of mass spectrometry is to ionize material particles (atoms, molecules) into ions, and separate them according to the spatial position and time sequence through an appropriate stable or changing electric field or magnetic field to achieve mass-to-nuclear ratio separation, and detect their intensity for qualitative, Analytical methods for quantitative analysis. Because mass spectrometry directly measures material particles, and mass spectrometry has the characteristics of high sensitivity, high resolution, high throughput and high applicability, mass spectrometer and mass spectrometry technology play an important role in modern scien...

AI Technical Summary

Problems solved by technology

The main reason is that the solution to achieve high-precision quantitative analysis and qualitative analysis in the same mass spectrometer system faces a basic contradiction: without sacrificing the performance of qualitative and quantitative analysis, the fewer subsystems shared by qualitative and quantitative analysis, The more independent the system, the less technically difficult it is to realize (and the less innovative components), the less the cost, and the less analytical results it brings, for example, only the ion source is shared, and other subsystems are independent

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