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Chinese lobelia freshly-squeezed spray drying granular medicinal slices and preparation technology thereof

A dry granule and preparation technology, which is applied in the direction of medical preparations containing active ingredients, plant raw materials, digestive system, etc., can solve the problems of time-consuming and energy-consuming, large loss of active ingredients, and difficulty in extracting non-polar active ingredients. , to achieve the effects of good fluidity, stable quality of decoction pieces, and convenience for storage, transportation and clinical adjustment

Inactive Publication Date: 2016-12-14
徐漫
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The preparation process of granular decoction pieces, the extraction is not only time-consuming and energy-consuming, but also because a large amount of water is often used as a solvent, it is difficult to extract the non-polar active ingredients in the medicinal materials
In addition, since the lobelia medicinal material used for extraction is also dried and stored for a long time, the loss of active ingredients is also very large

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0011] Freshly collected lobelia medicinal materials are selected, washed with water to remove sediment, pressed with a press to extract juice while fresh, and 1% by weight of the virgin medicinal juice is reserved for another use. Add 3 times the amount of tap water to the obtained dregs, stir for 20 minutes, and press with a plate-and-frame filter press to extract the juice. The remaining medicinal dregs are squeezed with a press to extract the juice. The above-mentioned remaining first-pressed medicinal juice is combined with the subsequent two squeezed medicinal juices, and filtered with a 100-mesh sieve. The filtrate was concentrated under reduced pressure and the temperature was set at 65 °C. When the relative density of the concentrated extract is 1.05, it is spray-dried, the air inlet temperature is 140°C, and the air outlet temperature is 100°C. The spray-dried matter is collected, crushed at low temperature, and passed through an 80-mesh sieve. Mix this spray-dried...

Embodiment 2

[0013] Freshly collected lobelia medicinal materials are selected, washed with water to remove sediment, pressed with a press to extract juice while fresh, and 5% of the weight of the virgin medicinal juice is reserved for another use. Add 5 times the amount of tap water to the obtained dregs, stir for 30 minutes, and press with a plate-and-frame filter press to extract the juice. The remaining medicinal dregs are squeezed with a press to extract the juice. The above-mentioned remaining first-pressed medicinal juice is combined with the subsequent two squeezed medicinal juices, and filtered with a 100-mesh sieve. The filtrate was concentrated under reduced pressure and the temperature was set at 70 °C. When the relative density of the concentrated extract is 1.10, it is spray-dried, the air inlet temperature is 120°C, and the air outlet temperature is 90°C. The spray-dried matter is collected, crushed at low temperature, and passed through an 80-mesh sieve. Mix this spray-dr...

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Abstract

The invention discloses Chinese lobelia freshly-squeezed spray drying granular medicinal slices and a preparation technology thereof. The technology comprises the steps of Chinese lobelia medicine harvesting, selecting, drip washing, fresh squeezing and performing leaching to obtain liquid medicine; water is added into medicine residues to be stirred, and filtering and squeezing are performed. After the liquid medicine is combined, depression and concentration are performed, spray-drying is performed, a spray-drying product is collected and smashed to be mixed with preliminary squeezing liquid medicine for granulation, and vacuum packaging is performed after size stabilization. According to the Chinese lobelia freshly-squeezed spray drying granular medicinal slices obtained through the method, polar and non-polar effective components in medicine are reserved to the maximum extent, the granular medicinal slices are good in flowability, convenient to storage and control, controllable in quality and reliable in curative effect, and is of great significance in ensuring the traditional Chinese medicine clinical effect, and the method has remarkable social and economic benefits after being implemented and popularized.

Description

technical field [0001] The invention belongs to the field of processing Chinese medicinal materials, and in particular relates to a processing technology of Chinese medicinal lobelia decoction pieces. Background technique [0002] The traditional Chinese medicine Lobelia is the dried whole herb of Lobelia chinensis Lour., a perennial herb of the genus Lobelia in the Campanulaceae family. This product is sweet and flat in nature, contains a variety of alkaloids, has the effects of clearing heat and detoxifying, diuretic and reducing swelling, and has the effect of treating poisonous snake bites, liver cirrhosis ascites, advanced schistosomiasis ascites, appendicitis, etc. [0003] The commonly used processing methods of lobelia decoction pieces are: harvest in summer and autumn, remove impurities, dry in the sun, and pack for storage and transportation. Such herbal decoction pieces are bulky, have poor hygienic indicators, are prone to pollution and mildew, and are difficult...

Claims

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Application Information

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IPC IPC(8): A61K36/34A61P17/02A61P7/10A61P1/16A61P1/00A61P33/12
CPCA61K36/34A61K2236/331A61K2236/39A61K2236/51A61K2236/53
Inventor 徐漫
Owner 徐漫
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