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Traditional Chinese medicine decoction for treating osteonecrosis of femoral head

A technology for femoral head necrosis and traditional Chinese medicine decoction, applied in the field of traditional Chinese medicine decoction, can solve problems such as unreasonable prescription compatibility, enhanced drug toxicity, weakened therapeutic effect, etc., to improve microcirculation, enhance metabolism, accelerate regeneration and repair, and promote metabolism. and absorption effect

Inactive Publication Date: 2016-12-14
卞永兴
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the pathological mechanism of femoral head necrosis has not been fully elucidated, and various theories have been proposed for its pathogenesis, but there is no public opinion so far.
Conventional Chinese medicine treatment is difficult to take care of comprehensively with only a few herbs, and a variety of drugs must be properly combined to improve the efficacy or reduce adverse reactions, so as to adapt to the treatment of complex diseases
In view of the complex interaction of various active ingredients of various Chinese medicinal materials in the body, changes in the pharmacokinetics and pharmacodynamics of various drugs in the body will have various effects on the interaction between drugs. When used in combination, it may not only produce synergistic drug effects, but also may produce antagonistic effects, which will lead to weakening of drug therapeutic effect or treatment failure. Some drugs in combination will also increase drug toxicity and cause adverse reactions; Enhanced, but when the therapeutic effect is excessively enhanced, it will exceed the body's ability to tolerate it, and it can also cause adverse reactions and even endanger patients.
Part of the research is to prepare traditional Chinese medicine prescriptions for the treatment of femoral head necrosis. The most common problem is the unreasonable compatibility of the prescriptions. It is often only based on the individual functions and indications of some single or compound medicines and some pharmacodynamic indicators. According to the theory of medicine, the random addition and subtraction of the flavor of the prescription results in unreasonable prescriptions, which contradicts the theory of traditional Chinese medicine.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] Weighing: 18 grams of Bayleaf Palm, 16 grams of tap blood, 14 grams of melon seeds, 12 grams of Hualianqi, 9 grams of Chuanxiong, 9 grams of Guizhi, 8 grams of Salvia, 8 grams of Achyranthes bidentata, 7 grams of Millet, hook 7 grams of rattan, 6 grams of mulberry, 6 grams of scorpion, 5 grams of willow tea, 5 grams of walnut kernel, 6 grams of achyranthes bidentata, 7 grams of kudzu root, 9 grams of psoralen, 9 grams of drynaria, 10 grams of dog spine, 10 grams of duck stove bright end, 8 grams of oysters, 8 grams of herb, 6 grams of Bupleurum, 7 grams of angelica, 8 grams of licorice, and 6 grams of Artemisia japonica.

[0044] The preparation method is as follows: crush the above medicinal materials into coarse powder; decoct twice, add 8 times the amount of water for the first decoction, soak for 2 hours, decoct for 3 hours, filter; add 6 times the amount of water for the second decoction, and decoct for 2 hours , filter; combine the two decoctions and mix evenly be...

Embodiment 2

[0062] Weighing: 16 grams of tap blood, 14 grams of melon seeds, 12 grams of Hualianqi, 9 grams of Chuanxiong, 9 grams of Guizhi, 8 grams of Danshen, 8 grams of Achyranthes bidentata, 7 grams of Milletah, 7 grams of Uncaria, and mulberry 6 grams, 6 grams of scorpion, 5 grams of willow tea, 5 grams of walnut kernel, 6 grams of achyranthes bidentata, 7 grams of kudzu root, 9 grams of psoralen, 9 grams of drynaria, 10 grams of dog spine, 10 grams of duck stove bright end , 8 grams of oysters, 8 grams of herb, 6 grams of Bupleurum, 7 grams of angelica, 8 grams of licorice. The preparation method is the same as in Example 1.

[0063] Among the 10 patients with femoral head necrosis who selected the Chinese medicine decoction made by the embodiment of the present invention 2, 6 cases were cured, 2 cases took a turn for the better, 2 cases did not heal, and adverse reaction 0 case, the cure rate was 60%, and the total effective rate was 80%. The average healing time is 21 days. The...

Embodiment 3

[0065] Weighing: 16 grams of tap blood, 12 grams of Hualianqi, 9 grams of Chuanxiong, 9 grams of Guizhi, 8 grams of Salvia, 8 grams of Achyranthes bidentata, 7 grams of Milletah, 7 grams of Uncaria, 6 grams of Sangji, Scorpion 6 grams, 5 grams of willow tea, 5 grams of walnut kernels, 6 grams of achyranthes, 7 grams of kudzu root, 9 grams of psoralen, 9 grams of drynaria, 10 grams of dog spines, 8 grams of oysters, 8 grams of atractylodes, 6 grams of Bupleurum gram, 7 grams of angelica, 8 grams of licorice. The preparation method is the same as in Example 1.

[0066] Among the 10 patients with femoral head necrosis who selected the Chinese medicine decoction made by the embodiment of the present invention 3, 5 cases were cured, 2 cases took a turn for the better, 3 cases did not heal, and adverse reaction 0 case, the cure rate was 50%, and the total effective rate was 70%. The average healing time is 23 days. The cured and improved patients were followed up for 24 months, an...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine decoction for treating the osteonecrosis of the femoral head, which is prepared from the following Chinese medicinal materials by weight proportions: 18 parts of corypha umbraculifera leaf, 16 parts of Japanese ophiorrhiza herb, 14 parts of muskmelon seed, 12 parts of herba polygoni runcinati, 9 parts of szechuan lovage rhizome, 9 parts of cassia twig, 8 parts of radix salviae miltiorrhizae, 8 parts of twotooth achyranthes root, 7 parts of suberect spatholobus stem, 7 parts of ramulus uncariae cum uncis, 6 parts of Chinese taxillus twig, 6 parts of whole scorpion, 5 parts of sibiraea laevigata infructescence, 5 parts of walnut kernel, 6 parts of twotooth achyranthes root, 7 parts of kudzuvine root, 9 parts of malaytea scurfpea fruit, 9 parts of drynaria rhizome, 10 parts of east Asian tree fern rhizome, 10 parts of Scheffleraminutistellata stem and leaf, 8 parts of oyster, 8 parts of swordlike atractylodes rhizome, 6 parts of red thorowax root, 7 parts of Chinese angelica, 8 parts of liquorice root and 6 parts of hairy wormwood herb. Clinical experiments prove that by means of the reasonable compatibility of the traditional Chinese materials, the traditional Chinese medicine decoction can help to treat the osteonecrosis of the femoral head, the effect is quick, the osteonecrosis of the femoral head cannot easily recur, and a good effect of overall regulation and good long-term effects are achieved.

Description

technical field [0001] The invention relates to a traditional Chinese medicine decoction, in particular to a traditional Chinese medicine decoction for treating femoral head necrosis. Background technique [0002] Avascular necrosis of the femoral head is a disease in which the blood supply vessels of the femoral head are damaged or interrupted, causing the apoptosis of bone cells, which in turn leads to changes in the bone structure of the femoral head, and then develops into a disease of femoral head collapse and joint dysfunction. It is one of the more common bone and joint difficult diseases in clinical practice. At present, osteonecrosis of the femoral head has been widely studied by orthopedic doctors, and various theories have been put forward for its etiology and pathogenesis. Trauma, long-term steroid use, and excessive alcohol consumption have been widely recognized as the most common causes of osteonecrosis of the femoral head. However, the pathological mechanis...

Claims

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Application Information

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IPC IPC(8): A61K36/889A61P19/08A61K35/618A61K35/646
CPCA61K36/889A61K9/0095A61K35/618A61K35/646A61K36/11A61K36/126A61K36/185A61K36/21A61K36/232A61K36/233A61K36/236A61K36/24A61K36/25A61K36/282A61K36/284A61K36/37A61K36/42A61K36/482A61K36/484A61K36/486A61K36/487A61K36/488A61K36/52A61K36/537A61K36/54A61K36/704A61K36/73A61K36/74A61K2236/331A61K2236/39A61K2300/00
Inventor 卞永兴其他发明人请求不公开姓名
Owner 卞永兴
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