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Pharmaceutical for treating gastric ulcer and preparation method thereof

A technology for gastric ulcer and medicine, applied in the field of medicine for treating gastric ulcer and its preparation, to achieve the effect of safe and mild ingredients and increase the residence time

Active Publication Date: 2017-01-04
达嘉维康生物制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Existing drugs for the treatment of gastric ulcers mainly use calcium-containing raw materials to neutralize gastric acid. This method actually relieves the erosion of gastric acid on the wound, but it is not a permanent cure. For patients, stopping taking drugs It will restore the original condition, especially for patients with chronic gastric ulcer, this phenomenon is particularly obvious

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Add water to decoct 112g Agrimony twice, each time for 2 hours, combine the decoction and filter, let the filtrate stand for 24 hours, and concentrate the supernatant to a clear paste with a relative density of 80-85°C of 1.18-1.20;

[0023] Grind the following components into 400 meshes in advance, add clear paste, mix and evenly granulate: 16g chitosan with a deacetylation degree of 70% and a molecular weight of 80000, 32g corrugated seeds, 48g egg shells, 32g dry alum, 3g rhodiola rosea , 32g of water safflower seeds, dried into granules, packed into capsules, then added clove oil into the capsules, and finally added honey into the capsules to obtain the product. The clove oil is 40g in total, and the honey used is 10g in total. Finally, capsules are prepared and filled in proportion so that each capsule contains 0.5g of the above composition.

Embodiment 2

[0025] Add water to decoct 120g Agrimony twice, each time for 2.5 hours, combine the decoction and filter, let the filtrate stand for 24 hours, and concentrate the supernatant to a clear paste with a relative density of 1.18-1.20 at 80-85°C;

[0026] Grind the following components into 300 meshes in advance, add clear paste, mix and evenly granulate: 25g of chitosan with a deacetylation degree of 80% and a molecular weight of 90000, 36g of corrugated seeds, 60g of egg shells, 38g of dry alum, 4g of Rhodiola rosea , 25g of safflower seeds, dried into granules, packed into capsules, then added clove oil into the capsules, and finally added honey into the capsules to obtain the product. The clove oil is 30g in total, and the honey used is 5g in total. Finally, capsules are prepared and filled in proportion so that each capsule contains 0.5g of the above composition.

Embodiment 3

[0028] Add water to decoct 100g Agrimony twice, each time for 3 hours, combine the decoction and filter, let the filtrate stand for 24 hours, and concentrate the supernatant to a clear paste with a relative density of 1.18-1.20 at 80-85°C;

[0029] Grind the following components into 200 meshes in advance, add clear paste, mix and granulate evenly: 15g of chitosan with a degree of deacetylation of 70% and a molecular weight of 100,000, 28g of corrugated seeds, 40g of egg shells, 28g of dried alum, 2g of Rhodiola rosea , 35g of safflower seeds, dried into granules, packed into capsules, and clove oil added to the capsules to obtain the product. The clove oil is 45g in total, and finally the capsules are prepared and filled in proportion so that each capsule contains 0.5g of the above-mentioned composition.

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PUM

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Abstract

The invention relates to a pharmaceutical for treating gastric ulcer and a preparation method thereof. The provided pharmaceutical for treating the gastric ulcer comprises, by weight, 30-45 parts of clove oil, 15-25 parts of chitosan, 28-36 parts of concha arcae, 40-60 parts of egg shell, 28-38 parts of dried alum, 2-4 parts of Rhodiola rosea, 25-35 parts of Polygonum orientale, 0.2-0.6 parts of pearl powder and 100-120 parts of hairyvein agrimony. The provided pharmaceutical for treating the gastric ulcer has the safe and gentle ingredients, is capable of effectively increasing the standing time of the pharmaceutical in the stomach, and performing the sterilization protection to the ulcer part, and has the efficacy of nourishing and protecting the stomach. The gastric ulcer can be cured by administrating the pharmaceutical for a long time.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a medicine for treating gastric ulcer and a preparation method thereof. Background technique [0002] Gastric ulcer disease or peptic ulcer is a common digestive tract disease that can occur in the esophagus, stomach or duodenum, and can also occur near the gastro-jejunum anastomosis or in the Meckel's diverticulum containing gastric mucosa, because gastric ulcer Peptic ulcer and duodenal ulcer are the most common, so the so-called peptic ulcer generally refers to gastric ulcer and duodenal ulcer. The reason why it is called peptic ulcer is that gastric ulcer and duodenal ulcer were previously thought to be formed due to gastric acid and pepsin digesting the mucosa itself, but in fact gastric acid and pepsin are only one of the main causes of ulcer formation , there are other reasons for the formation of peptic ulcers. Because the etiology and clinical s...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/73A61P1/04A61K35/618A61K35/57A61K33/06A61K31/722A61K31/7004
CPCA61K9/1623A61K31/7004A61K31/722A61K33/06A61K35/57A61K35/618A61K36/41A61K36/61A61K36/70A61K36/73A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 彭舒怀王林易志红
Owner 达嘉维康生物制药有限公司
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