Preparation method of chitosan/biological glass composite fiber

Abstract

The invention relates to a method for preparing chitosan / bioglass composite fibers. The method includes steps of 1), dissolving chitosan with a low molecular weight by the aid of chitosan solvents to obtain carrier solution; 2), mixing bioglass powder and the carrier solution with each other under intense shear effects of stirring equipment to obtain bioglass mother liquor; 3), injecting the bioglass mother liquor into chitosan spinning solution in an online adding mode to obtain chitosan / bioglass spinning solution and extruding, coagulating and drawing the chitosan / bioglass spinning solution to obtain the chitosan / bioglass composite fibers. The method has the advantages that the bioglass powder of the chitosan / bioglass composite fibers prepared by the aid of the method is uniformly distributed, and carriers can be solidified and formed along with fibers without extra auxiliaries in solvent and coagulating bath systems; the method for forming the chitosan / bioglass composite fibers is simple and is high in efficiency, and functional chitosan fibers can be produced on the basis of conventional production lines.

Description

technical field

[0001] The invention belongs to the field of functional fibers and relates to a preparation method of chitosan / biological glass composite fibers. Background technique

[0002] Chitosan is obtained by deacetylation of chitin, which exists widely in nature, and chitosan fiber is formed by wet spinning. Bioglass is made of SiO 2 、Na 2 O, CaO and P 2 o 5 Silicate glass composed of basic components. Both chitosan fiber and bioglass can be used as wound dressings to promote wound repair. However, the bioglass dressing exists in a powder state, which is troublesome to use. In order to prevent the biological glass powder covering the wound from falling off, it needs to be covered with gauze and non-woven materials for protection.

[0003] The preparation of chitosan / biological glass composite fiber can combine the advantages of both, and solve the problem of inconvenient use of biological glass powder. There is no report on chitosan / bioglass composite fiber a...

Examples

Embodiment 1

[0030] A preparation method of chitosan / biological glass composite fiber, comprising the steps of:

[0031] 1) The acetic acid solution with a concentration of 1 wt% is used to dissolve the weight-average molecular weight of 5×10 5 , deacetylation degree is 90% low-molecular-weight chitosan, and the concentration of prepared low-molecular-weight chitosan is 3wt% carrier solution;

[0032] 2) Bioglass powder (containing 40wt% SiO2) with an average particle size of 0.09 μm 2 , 35wt%Na 2 O, 5wt% CaO and 20wt% P 2 o 5 Silicate glass powder) and the carrier solution were mixed by a screw extruder at a stirring rate of 100 rpm for 0.5 hour to prepare a biological glass mother liquor, wherein the mass ratio of low molecular weight chitosan to biological glass powder is 10:1;

[0033] 3) Injecting the biological glass mother liquor into a concentration of 3wt% in the mode of online addition, the weight-average molecular weight of chitosan is 8×10 5 , a chitosan spinning solution...

Embodiment 2

[0036] A preparation method of chitosan / biological glass composite fiber, comprising the steps of:

[0037]1) The acetic acid solution with concentration of 1.2wt% is used to dissolve the weight-average molecular weight of 5.1×10 5 , deacetylation degree is 90% low-molecular-weight chitosan, the concentration that makes low-molecular-weight chitosan is 3.2wt% carrier solution;

[0038] 2) Bioglass powder (containing 45wt% SiO2) with an average particle size of 0.08 μm 2 , 32wt%Na 2 O, 10wt% CaO and 2wt% P 2 o 5 Silicate glass powder) and the carrier solution were mixed by a screw extruder with a stirring rate of 110 rev / min for 0.6 hours to prepare a biological glass mother liquor, wherein the mass ratio of low molecular weight chitosan to biological glass powder is 10:1;

[0039] 3) Injecting the biological glass mother liquor into a concentration of 3.2wt% in the mode of online addition, the weight-average molecular weight of chitosan is 8.3×10 5 , a chitosan spinning ...

Embodiment 3

[0042] A preparation method of chitosan / biological glass composite fiber, comprising the steps of:

[0043] 1) The acetic acid solution with a concentration of 1.5wt% is used to dissolve the weight-average molecular weight of 5.2×10 5 , deacetylation degree is 90.5% low-molecular-weight chitosan, the concentration that makes low-molecular-weight chitosan is 3.5wt% carrier solution;

[0044] 2) Bioglass powder (containing 50wt% SiO2) with an average particle size of 0.47 μm 2 , 30wt%Na 2 O, 8wt% CaO and 6wt% P 2 o 5 Silicate glass powder) and the carrier solution were mixed by a kneader at a stirring rate of 120 rpm for 0.7 hours to obtain a biological glass mother liquor, wherein the mass ratio of low molecular weight chitosan to the biological glass powder was 9 :1;

[0045] 3) Injecting the biological glass mother liquor into a concentration of 3.4wt% in the mode of online addition, the weight-average molecular weight of chitosan is 8.6×10 5 , a chitosan spinning solut...

technical field

[0001] The invention belongs to the field of functional fibers and relates to a preparation method of chitosan / biological glass composite fibers. Background technique

[0002] Chitosan is obtained by deacetylation of chitin, which exists widely in nature, and chitosan fiber is formed by wet spinning. Bioglass is made of SiO 2 、Na 2 O, CaO and P 2 o 5 Silicate glass composed of basic components. Both chitosan fiber and bioglass can be used as wound dressings to promote wound repair. However, the bioglass dressing exists in a powder state, which is troublesome to use. In order to prevent the biological glass powder covering the wound from falling off, it needs to be covered with gauze and non-woven materials for protection.

[0003] The preparation of chitosan / biological glass composite fiber can combine the advantages of both, and solve the problem of inconvenient use of biological glass powder. There is no report on chitosan / bioglass composite fiber a...

Examples

Embodiment 1

[0030] A preparation method of chitosan / biological glass composite fiber, comprising the steps of:

[0031] 1) The acetic acid solution with a concentration of 1 wt% is used to dissolve the weight-average molecular weight of 5×10 5 , deacetylation degree is 90% low-molecular-weight chitosan, and the concentration of prepared low-molecular-weight chitosan is 3wt% carrier solution;

[0032] 2) Bioglass powder (containing 40wt% SiO2) with an average particle size of 0.09 μm 2 , 35wt%Na 2 O, 5wt% CaO and 20wt% P 2 o 5 Silicate glass powder) and the carrier solution were mixed by a screw extruder at a stirring rate of 100 rpm for 0.5 hour to prepare a biological glass mother liquor, wherein the mass ratio of low molecular weight chitosan to biological glass powder is 10:1;

[0033] 3) Injecting the biological glass mother liquor into a concentration of 3wt% in the mode of online addition, the weight-average molecular weight of chitosan is 8×10 5 , a chitosan spinning solution...

Embodiment 2

[0036] A preparation method of chitosan / biological glass composite fiber, comprising the steps of:

[0037]1) The acetic acid solution with concentration of 1.2wt% is used to dissolve the weight-average molecular weight of 5.1×10 5 , deacetylation degree is 90% low-molecular-weight chitosan, the concentration that makes low-molecular-weight chitosan is 3.2wt% carrier solution;

[0038] 2) Bioglass powder (containing 45wt% SiO2) with an average particle size of 0.08 μm 2 , 32wt%Na 2 O, 10wt% CaO and 2wt% P 2 o 5 Silicate glass powder) and the carrier solution were mixed by a screw extruder with a stirring rate of 110 rev / min for 0.6 hours to prepare a biological glass mother liquor, wherein the mass ratio of low molecular weight chitosan to biological glass powder is 10:1;

[0039] 3) Injecting the biological glass mother liquor into a concentration of 3.2wt% in the mode of online addition, the weight-average molecular weight of chitosan is 8.3×10 5 , a chitosan spinning ...

Embodiment 3

[0042] A preparation method of chitosan / biological glass composite fiber, comprising the steps of:

[0043] 1) The acetic acid solution with a concentration of 1.5wt% is used to dissolve the weight-average molecular weight of 5.2×10 5 , deacetylation degree is 90.5% low-molecular-weight chitosan, the concentration that makes low-molecular-weight chitosan is 3.5wt% carrier solution;

[0044] 2) Bioglass powder (containing 50wt% SiO2) with an average particle size of 0.47 μm 2 , 30wt%Na 2 O, 8wt% CaO and 6wt% P 2 o 5 Silicate glass powder) and the carrier solution were mixed by a kneader at a stirring rate of 120 rpm for 0.7 hours to obtain a biological glass mother liquor, wherein the mass ratio of low molecular weight chitosan to the biological glass powder was 9 :1;

[0045] 3) Injecting the biological glass mother liquor into a concentration of 3.4wt% in the mode of online addition, the weight-average molecular weight of chitosan is 8.6×10 5 , a chitosan spinning solut...