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A kind of oral ulcer patch containing chlorophyll and its preparation method

A technology for oral ulcers and chlorophyll, applied in the field of medicine, can solve problems such as side effects, drug dependence, and restrictions on drug promotion and application, and achieve the effects of extending shelf life, promoting contraction, and accelerating swelling and healing

Active Publication Date: 2017-09-26
GUANGDONG COOWAY BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] However, the main drugs of oral patch currently used are hormonal drugs such as dexamethasone and dexamethasone acetate. Long-term use will produce drug dependence and serious side effects, which greatly limits the promotion and application of this drug.

Method used

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  • A kind of oral ulcer patch containing chlorophyll and its preparation method
  • A kind of oral ulcer patch containing chlorophyll and its preparation method
  • A kind of oral ulcer patch containing chlorophyll and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034]Embodiment 1, a kind of oral ulcer patch containing chlorophyll

[0035] The oral ulcer patch containing chlorophyll consists of the following components and parts by weight thereof:

[0036] 12 parts of chlorophyll, 6 parts of carrotin, vitamin B 6 2 parts, 4 parts of ropivacaine, 40 parts of film-forming agent, 10 parts of lauryl glucoside, 16 parts of tributyl citrate and 320 parts of distilled water; Described film-forming agent is made of sodium alginate, polyvinyl alcohol and Citric acid is composed of 4:5:1.2 by weight.

[0037] Preparation:

[0038] S1 Take half of the amount of distilled water and heat it to 70°C, add half of the amount of film-forming agent and stir until it is completely dissolved, filter while it is hot, take the filtrate, add tributyl citrate to the filtrate, and stir evenly to obtain a glue solution;

[0039] S2 Cool the mucilage solution obtained in step S1 to 40°C, add chlorophyll, carotin, vitamin B6, stir evenly, then add ropivacaine...

Embodiment 2

[0042] Embodiment 2, a kind of oral ulcer patch containing chlorophyll

[0043] The oral ulcer patch containing chlorophyll consists of the following components and parts by weight thereof:

[0044] 18 parts of chlorophyll, 8 parts of carrotin, vitamin B 6 3 parts, 6 parts of ropivacaine, 50 parts of film-forming agent, 12 parts of lauryl glucoside, 20 parts of tributyl citrate and 400 parts of distilled water; Described film-forming agent is made of sodium alginate, polyvinyl alcohol and Citric acid is composed in a weight ratio of 5:4:1.

[0045] Preparation:

[0046] S1 Take half of the amount of distilled water and heat it to 75°C, add half of the amount of film-forming agent and stir until it is completely dissolved, filter while it is hot, take the filtrate, add tributyl citrate to the filtrate, and stir evenly to obtain a glue solution;

[0047] S2 Cool the mucilage solution obtained in step S1 to 42°C, add chlorophyll, carotin, vitamin B6, stir evenly, then add ropi...

Embodiment 3

[0050] Embodiment 3, a kind of oral ulcer patch containing chlorophyll

[0051] The oral ulcer patch containing chlorophyll consists of the following components and parts by weight thereof:

[0052] 24 parts of chlorophyll, 10 parts of carrotin, vitamin B 6 4 parts, 8 parts of ropivacaine, 58 parts of film-forming agent, 16 parts of lauryl glucoside, 26 parts of tributyl citrate and 450 parts of distilled water; Described film-forming agent is made of sodium alginate, polyvinyl alcohol and Citric acid is composed of 6:3:0.8 by weight.

[0053] Preparation:

[0054] S1 Take half of the amount of distilled water and heat it to 80°C, add half of the amount of film-forming agent and stir until it is completely dissolved, filter while it is hot, take the filtrate, add tributyl citrate to the filtrate, and stir evenly to obtain a glue solution;

[0055] S2 Cool the mucilage solution obtained in step S1 to 45°C, add chlorophyll, carotin, and vitamin B6, and stir evenly, then add r...

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Abstract

The invention belongs to the technical field of medicines, and particularly relates to a dental ulcer pasting film containing chlorophyll and a preparation method thereof. The dental ulcer pasting film containing chlorophyll is mainly prepared from chlorophyll, daucosterol, vitamin B6, ropivacaine, a film forming agent, glucoside, tributyl citrate and distilled water. The dental ulcer pasting film containing chlorophyll is reasonable and scientific in compatibility, the remarkable anti-bacteria, anti-inflammation and analgesic effects are achieved due to the interaction of the components, the state of the illness of a patient suffering from dental ulcer can be effectively relieved, and the curative time can be shortened. The dental ulcer pasting film containing chlorophyll has the advantages of being high in adhesive strength, high in dissolution rate and complete in film uncovering integrity, can effectively ensure that the medical effect is brought into play and is ideal.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a chlorophyll-containing oral ulcer patch and a preparation method thereof. Background technique [0002] Oral ulcer is a common oral mucosal disease with complex etiology and easy recurrence. In daily life, oral ulcers caused by bites, burns, abrasions, scratches, etc. are more common. Once oral ulcers are formed, it not only affects the normal life and diet of patients, but sometimes even causes systemic diseases. The medicine for the treatment of oral ulcer at present mainly contains: immunostimulator and hormonal medicine. This kind of medicine is widely used in foreign countries. It can effectively treat some deep and long-term ulcers, and can effectively inhibit the recurrence of ulcers for up to 3-6 months. [0003] Due to the special physiological environment of the oral cavity, most medicine patches stay in the oral cavity for a short time, and it is diff...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/704A61K31/445A61K31/4415A61K31/409A61K9/70A61K47/36A61K47/32A61K47/12A61P1/02A61P31/04
CPCA61K9/006A61K9/7007A61K31/409A61K31/4415A61K31/445A61K31/704A61K47/12A61K47/32A61K47/36A61K2300/00
Inventor 陈松彬易萍倪彦艳刘杰森张爱萍李小翠
Owner GUANGDONG COOWAY BIOTECH CO LTD