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Preparation method of swelling-eliminating and pain-alleviating traditional Chinese medicine composition

A technology for reducing swelling, relieving pain, and composition, which is applied in the field of preparation of Chinese patent medicine preparations. It can solve the problems of long extraction time, affecting the extraction effect, and incomplete extraction, and achieve the effects of shortening extraction time, saving grinding energy consumption, and improving grinding efficiency.

Inactive Publication Date: 2017-03-15
广西壮族自治区花红药业集团股份公司
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Chinese invention patent CN101099846A records the composition and preparation process of anti-tumor and pain-relieving tincture. The preparation process adopts percolation process to enrich the active ingredients, and the extraction time is long, and the extraction is incomplete, and deposits are easy to form
Enzyme extraction technology can effectively extract Chinese medicine ingredients from Chinese medicinal materials at normal temperature and pressure, and the extraction purity is high, and will not destroy the efficacy of Chinese medicine ingredients. It can replace the traditional ethanol extraction method, but enzyme extraction There is a problem of insufficient contact between the low-concentration enzyme solution and the fiber of the medicinal material, which affects its extraction effect

Method used

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  • Preparation method of swelling-eliminating and pain-alleviating traditional Chinese medicine composition
  • Preparation method of swelling-eliminating and pain-alleviating traditional Chinese medicine composition
  • Preparation method of swelling-eliminating and pain-alleviating traditional Chinese medicine composition

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] 1. Weigh the following raw materials in parts by weight: Muxiang 22g, Fangfeng 50g, Nepeta 30g, Asarum 15g, Wujiapi 45g, Guizhi 18g, Achyranthes bidentata 70g, Chuanxiong 50g, Xu Changqing 37g, Angelica dahurica 50g, Curcuma 36g, Red Eucommia 48g, Daluo Umbrella 30g, Xiaoluo Umbrella 20g, LMZ 50g, Huangteng 35g, Gardenia 30g, Sanleng 50g, Agarwood 9g, Camphor 30g, Menthol 50g.

[0030] 2. Take 5 medicinal materials such as Muxiang, Fangfeng, Chuanxiong, Sanleng, and Agarwood. After coarse crushing, use a micron ball mill to grind for 3 hours to obtain a medicinal powder with a particle size of less than 200 microns.

[0031] 3. Take Nepeta, Asarum, Wujiapi, Guizhi, Achyranthes bidentata, Xu Changqing, Angelica dahurica, Curcuma, Daluosan, Xiaoluosan, Red Eucommia, LMZ, Huangteng, Gardenia and other 14 herbs, crude After crushing, use a micron ball mill to grind for 0.5h to obtain a drug powder with a particle size of less than 200 microns, mix it with the drug powder ob...

Embodiment 2

[0037] 1. Weigh the following raw materials by weight: 10g Muxiang, 10g Fangfeng, 10g Nepeta, 10g Asarum, 10g Wujiapi, 10g Guizhi, 10g Achyranthes bidentata, 10g Chuanxiong, 10g Xu Changqing, 20g Angelica dahurica, 10g Curcuma, Red Eucommia 20g, Daluo Umbrella 30g, Xiaoluo Umbrella 20g, LMZ 30g, Huangteng 25g, Gardenia 30g, Sanleng 20g, Agarwood 5g, Camphor 16g, Menthol 16g.

[0038] 2. Take 5 kinds of medicinal materials such as Muxiang, Fangfeng, Chuanxiong, Sanleng, and Agarwood. After coarse crushing, use a micron ball mill to grind for 2 hours to obtain a medicinal powder with a particle size of less than 100 microns.

[0039] 3. Take Nepeta, Asarum, Wujiapi, Guizhi, Achyranthes bidentata, Xu Changqing, Angelica dahurica, Curcuma, Daluosan, Xiaoluosan, Red Eucommia, LMZ, Huangteng, Gardenia and other 14 herbs, crude After crushing, use a micron ball mill to grind for 0.2h, and the particle size is less than 100 microns, mix with the drug powder obtained in step 2, vacuum ...

Embodiment 3

[0045] 1. Weigh the following raw materials by weight: 50g Muxiang, 50g Fangfeng, 50g Nepeta, 50g Asarum, 50g Wujiapi, 50g Guizhi, 50g Achyranthes bidentata, 50g Chuanxiong, 50g Xu Changqing, 50g Angelica dahurica, 50g Curcuma, Red Eucommia 50g, Daluo Umbrella 60g, Xiaoluo Umbrella 50g, LMianzhen 60g, Huangteng 60g, Gardenia 60g, Sanleng 50g, Agarwood 60g, Camphor 50g, Menthol 50g.

[0046] 2. Take 5 kinds of medicinal materials such as Muxiang, Fangfeng, Chuanxiong, Sanleng and Agarwood. After coarse crushing, use a micron ball mill to grind for 2.5 hours. The particle size is less than 150 microns.

[0047] 3. Take Nepeta, Asarum, Wujiapi, Guizhi, Achyranthes bidentata, Xu Changqing, Angelica dahurica, Curcuma, Daluosan, Xiaoluosan, Red Eucommia, LMZ, Huangteng, Gardenia and other 14 herbs, crude After crushing, use a micron ball mill to grind for 0.3h to obtain a drug powder with a particle size of less than 150 microns, mix it with the drug powder obtained in step 2, vacuum ...

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Abstract

The invention discloses a preparation method of a swelling-eliminating and pain-alleviating traditional Chinese medicine composition and belongs to the field of preparation methods of Chinese patent medicine preparations. The preparation method includes weighing Radix Aucklandiae, Radix Saposhnikoviae, Herba Schizonepetae, Herba Asari, Cortex Acanthopanacis, Ramulus Cinnamomi, Radix Achyranthis Bidentatae, Rhizoma Chuanxiong, Radix Cynanchi Paniculati, Radix Angelicae Dahuricae, Rhizoma Curcumae, Cortex Parabarii, Radix Ardisiae Crenatae, Herba Ardisiae Punctatae, Radix Zanthoxyli, Caulis Fibraureae Recisae, Fructus Gardeniae, Rhizoma Sparganii, Lignum Aquilariae Resinatum, Camphora and menthol, using a micrometer ball mill for grinding the above raw materials, drying, performing vacuum negative-pressure impregnation enzyme extraction and conducting microfiltration so as to obtain the swelling-eliminating and pain-alleviating traditional Chinese medicine composition. The preparation method has the advantages that extracted active ingredients are high in purity through an enzyme extraction technology and can be enriched through separation of an inorganic ceramic membrane, so that higher extraction efficiency is achieved; a low-concentration enzyme solution can be impregnated into fiber pores of the medicinal materials sufficiently, so that thorough extraction is achieved.

Description

technical field [0001] The invention relates to a preparation method of a Chinese patent medicine preparation, in particular to a preparation method of a Chinese medicine composition for reducing swelling and relieving pain with Chinese herbal medicines as raw materials. Background technique [0002] The preparation of traditional Chinese medicine preparations generally uses methods such as decoction, reflux, and percolation for extraction, but some extraction methods may easily cause changes in heat-sensitive active ingredients when the temperature rises during the extraction process, and some extraction methods have low extraction yields. , The extraction time is long. Due to the complex chemical composition of Chinese medicinal materials, traditional extraction methods will destroy the active ingredients in the medicinal materials. [0003] The swelling and pain-relieving tincture is the exclusive product of Huahong Pharmaceutical Co., Ltd. in Guangxi Zhuang Autonomous R...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P29/00A61K31/045A61K31/125
CPCA61K36/285A61K31/045A61K31/125A61K36/185A61K36/21A61K36/232A61K36/236A61K36/238A61K36/24A61K36/254A61K36/268A61K36/27A61K36/538A61K36/54A61K36/59A61K36/74A61K36/744A61K36/758A61K36/835A61K36/85A61K36/902A61K36/9066A61K2236/19
Inventor 韦飞燕张艳华韦金燕庞宇方振
Owner 广西壮族自治区花红药业集团股份公司
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