External cream for treating urticaria

A technology of urticaria and cream, which is applied in the field of external cream for the treatment of urticaria, can solve the problems of easy formation of drug resistance or ineffective effect, incomplete treatment, strong side effects, etc., and achieves non-toxic side effects, high safety, The effect of promoting skin immune function

Inactive Publication Date: 2017-05-31
BENGT I SAMUELSSON INST OF LIFE SCI CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] In order to solve the shortcomings of existing urticaria treatment products such as incomplete treatment, easy repetition, strong side effects, easy formation of drug resistance, or ineffective effects, the present invention proposes a cream for treating urticaria, including: mussel soft tissue extract, trypsin, licorice extract, sorrel extract, petrolatum, etc.

Method used

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  • External cream for treating urticaria
  • External cream for treating urticaria

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Example 1: The preparation method of mussel soft tissue extract.

[0028] Take mussels and remove their shells, collect 300 g of soft tissue, divide them into three parts, add 100 ml of the acidic solution in Table 1 below with a content of 0.3%, homogenate for 10 minutes, and centrifuge to obtain the supernatant, which is the mussel soft tissue extract.

[0029] The protein content and pH value in the supernatant were determined, and the protein content was determined by the Coomassie brilliant blue method.

[0030] Table 1

[0031] example acid solution protein content pH value 1 citric acid 2.6mg / ml 4.5 2 Acetic acid 3.5mg / ml 3.2 3 perchloric acid 3.0mg / ml 1.0

Embodiment 2

[0032] Example 2: A cream of mussel soft tissue extract, trypsin, licorice extract and sorrel extract.

[0033] Trypsin was purchased from Shaanxi Yuantai Biotechnology Co., Ltd., vitamin C, vitamin B2, and vitamin P were purchased from Zhengzhou Furunde Bioengineering Co., Ltd., honey was purchased from Jingdong Mall, and petroleum jelly was purchased from Suzhou Kangshuo Chemical Co., Ltd. The cream for treating urticaria in this embodiment is composed of the following proportions by weight: 100 mg of mussel soft tissue extract, 100 mg of trypsin, 15 mg of licorice extract and 15 mg of sorrel extract, vitamin P: 5 mg, vitamin B2 : 3mg, vitamin C: 16mg, add Vaseline to 100g, fully melt and mix to form ointment.

[0034] Eleven volunteers with chronic urticaria were collected to participate in the test. The cream prepared in this example was applied twice a day, and the drug was stopped after 14 days to record the curative effect. After 3 months, a return visit was made to rec...

Embodiment 3

[0045] Example 3: A cream of mussel soft tissue extract, trypsin, licorice extract and sorrel extract.

[0046] Trypsin was purchased from Shaanxi Yuantai Biotechnology Co., Ltd., vitamin C, vitamin B2, and vitamin P were purchased from Zhengzhou Furunde Bioengineering Co., Ltd., honey was purchased from Jingdong Mall, and petroleum jelly was purchased from Suzhou Kangshuo Chemical Co., Ltd. The cream for treating urticaria in this embodiment is composed of the following proportions by weight: mussel soft tissue extract 200mg, trypsin 200mg, licorice extract 20mg and sorrel extract 25mg, vitamin P: 10mg, vitamin B2 : 8mg, vitamin C: 25mg, add Vaseline to 100g, fully melt and mix to form ointment.

[0047] Collect 26 volunteers with acute urticaria to participate in the test, and divide them into a control group and a test group. The control group uses 999 Piyanping ointment for treating urticaria on the market, and the test group uses the cream prepared in this embodiment, whi...

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Abstract

The present invention relates to external cream for treating urticaria, the external cream for treating urticaria includes a mussel soft tissue extract, trypsin, a licorice extract, a creeping oxalis extract and vaseline, beneficial effects are that the external cream for treating urticaria has the anti-inflammatory, anti-allergy, repairing and muscle-generating effects, can promote skin cell metabolism by regulating the skin immune function, and has a good urticaria treatment effect. The external cream for treating urticaria does not contain glucocorticoid substances and antibiotics, and has no dependence property, no toxic and side effects after use for a long time, and has high clinical use safety and a large curing proportion.

Description

technical field [0001] The invention relates to the technical field of biomedicine, in particular to an external cream for treating urticaria. Background technique [0002] Urticaria, commonly known as wheal, wheal, wheal, wheal, is a common skin disease. The rash performance of this disease is similar to the skin damage caused by human contact with plant nettle, so it is called urticaria. Often have skin pruritus first, then wheal occurs, and is bright red or pale, skin color, and a few patients have edematous erythema. The size and shape of the wheal vary, and the outbreak time is indefinite. The wheal gradually spread and merged into sheets. Due to dermal papillary edema, it can be seen that the epidermal hair follicle mouth is sunken downward. Wheals last for several minutes to several hours, and a few can be extended to several days and subside without leaving any traces. The rash occurs repeatedly in batches, and is more common in the evening. Welts are often gene...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/48A61K9/06A61P17/00A61K31/352A61K31/525A61K35/618A61K35/644
CPCA61K35/618A61K9/0014A61K9/06A61K31/352A61K31/375A61K31/525A61K35/644A61K36/185A61K36/484A61K38/4826A61K47/06C12Y304/21004
Inventor 高敏
Owner BENGT I SAMUELSSON INST OF LIFE SCI CO LTD
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