Stress detection and molecular recognition system based on graphene composite structure

Abstract

The invention discloses a stress detection and molecular recognition system based on a graphene composite structure. The stress detection and molecular recognition system comprises a graphene composite structure arranged on a surface to be detected and a Raman detection device for detecting stress and identifying molecules through a Raman spectrum of the graphene composite structure; the graphene composite structure comprises a flexible substrate, a graphene layer and a noble metal nanoparticle enhanced layer in sequence from bottom to top; a stress value can be obtained by utilizing a vector resolution method through the position of a typical characteristic peak of graphene in a Raman scattering signal; a tissue detection point is moved along a plane so that two-dimensional stress sensing measurement of a tissue surface is realized; meanwhile, Raman molecular recognition on different molecules in a tissue is formed through transmission of the graphene; meanwhile, noble metal nanoparticles are arranged on the surface of the graphene so that a surface enhanced Raman substrate is realized; the Raman scattering signal is effectively detected and detection of extremely few nascent molecules is realized; and comprehensive detection of a tissue repairing condition is facilitated and the detection function and efficiency are improved.

Description

technical field [0001] The invention relates to the field of tissue repair detection, in particular to a stress detection and molecular recognition system based on a graphene composite structure. Background technique [0002] Graphene is a new type of two-dimensional material. It is a two-dimensional crystal composed of single-layer hexagonal cellular carbon. It has excellent characteristics such as high carrier mobility, high elastic modulus, and high light transmittance in the visible range. Since its discovery in 2004, research on the electrical, mechanical, and optical properties of graphene has attracted extensive attention in the industry. In recent years, graphene has been used as a transparent conductive film, and gas (chemical) sensors have been reported; at present, pressure / stress sensors based on graphene materials are one of the research hotspots. [0003] There is a literature report on a fiber-optic graphene pressure sensor: it fuses a section of quartz capil...

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Problems solved by technology

[0005] In summary, most of the current graphene pressure / stress sensors are based on the macroscopic geometric deformation of graphene or graphene composite structure to achieve measurement, and the signal reading methods are optical (reading the light before and after deformation path difference) and electrical (current change), and these sensors can only achieve single-point measurement, but are helpless for some two-dimensional surface stress measurements, such as when detecting tissue repair status, it is necessary to detect changes in tissue surface stress To judge its repair status, at the same time, during the tissue repair process, it is necessary to carry out molecular identification of the new tissue cells inside to comprehensively reflect the tissue repair status; however, the existing technology cannot directly detect the surface stress of the tissue repair status, and the new tissue cells Molecular identification is also more difficult

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