Efficient blood sampling and blood collecting device for ocular fundus of rats and mice

A technology for collecting blood for rats and mice, applied in the fields of medical science, sensors, diagnostic recording/measurement, etc., can solve the problem of high infection rate, blindness rate and mortality rate of rats and mice, and the blood flow rate and blood collection volume are not easy to control and cannot be carried out. Continuous multiple blood collection and other problems, achieve the effect of good controllability, improve the blood collection volume and blood collection efficiency at one time, and reduce the risk of operation failure and repeated injury

Pending Publication Date: 2017-07-21
WUXI NO 5 PEOPLES HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The advantage of this method is that the blood flow is faster, the wound is smaller, and the healing is faster. It is suitable for medium blood volume collection, and it is necessary to avoid the death of rats and mice. However, it also has the following disadvantages: high technical requirements for operators and difficult operation Larger, poor controllability, difficult to control the blood flow rate and blood collection volume, prone to blood coagulation, no bleeding, slightly inappropriate operation, and easy to cause secondary damage, infection rate, blinding rate and death in mice The rate is high, and it is impossible to carry out multiple consecutive blood collections, which greatly affects the recovery volume and recovery rate

Method used

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  • Efficient blood sampling and blood collecting device for ocular fundus of rats and mice
  • Efficient blood sampling and blood collecting device for ocular fundus of rats and mice
  • Efficient blood sampling and blood collecting device for ocular fundus of rats and mice

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Experimental program
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Effect test

Embodiment 1

[0028] Such as figure 1 As shown, the high-efficiency blood collection device for the fundus of rats and mice in this embodiment includes a blood collection part 1 and a blood collection part 2, and the blood collection part 1 and the blood collection part 2 are connected through a transparent plastic hose 3 and are all detachable and compact. Connection, the flexible pipe 3 has a length of 12cm; the blood collection part 1 includes a blunt metal tube part 101, which includes a blunt metal tube (material is the same as the injection needle), the total length is 6cm, and the inner diameter of the metal tube is 0.4mm; the blunt metal tube The lower half of the part 101 is fixed with a handle 102, the handle includes a central piece 103 and wings 104 connected to both sides of the central piece 103, the surface of the central piece 103 and the wings 104 are provided with anti-skid bumps 105; the central piece 103 There is a through hole 106 (such as figure 2 shown); the blood c...

Embodiment 2

[0032] Such as Figure 4 As shown, in this embodiment, the blunt-end metal tube part 101 includes a metal tube main part 107 and a branch part 108 located at the front end of the main part. The branch part 108 includes two parallel-arranged double blunt-end metal tubes 109, and the ends of the two converge communicate with the main body afterward. Other structures are with embodiment 1. The bimetallic tube blood collection structure can further improve the blood collection volume and blood collection efficiency at one time.

Embodiment 3

[0034] Such as Figure 5 ~ Figure 6As shown, in this embodiment, on the blunt-end metal pipe part 101, a fixing seat 6 is also provided above the handle part 102, and a through hole 601 for the blunt-end metal pipe part to penetrate is provided in the fixing seat 6; One side is connected with a protective cover 7, and the protective cover 7 is provided with an accommodating cavity 701 of a blunt-end metal pipe portion 101, and the fixed seat 6 and the protective cover 7 form a rotating connection through a buckle slot structure 8; the two sides of the fixed seat 5 and the container The lower parts of the two inner sidewalls corresponding to the cavity 701 are provided with a hook structure 9, and the hook structure 9 has a guiding slope. The hook structures 9 cooperate with each other and are fastened. Other structures are with embodiment 1.

[0035] When taking blood, the operator turns the protective cover 7 outwards. After the blood collection is completed, the operator r...

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Abstract

Provided is an efficient blood sampling and blood collecting device for ocular fundus of rats and mice. The device comprises a blood sampling part and a blood collecting part, wherein the blood sampling part is communicated with the blood collecting part through a hose; the blood sampling part comprises a blunt end metal tube part; the lower half part of the blunt end metal tube part is fixedly provided with a hand holding part; the hand holding part comprises a central sheet and a wing plate connected with one side or the two sides of the central sheet, and the surfaces of the central plate and the wing plate are provided with skid-proof convex points; the blood collecting part comprises an elastic plastic blood collecting tube, and the blood collecting tube comprises the upper end part of a collecting nozzle and the lower end part of a column; the blood collecting nozzle is connected with the end part of the hose in a detachable mode; the upper end part is connected with a nozzle cover matched with the blood collecting nozzle; the upper end part is connected with the lower end part through a buckle in a detachable mode; the lower end of the column has a flat bottom, a conical bottom or an arc bottom; in the process of manual extrusion and manual release, negative pressure is generated by the blood collecting tube to collect blood. The efficient blood sampling and blood collecting device has the advantages of being efficient and convenient in blood sampling and blood collecting, good in controllability, improving the success rate of blood sampling once and the blood collecting efficiency, and reducing the risks of operation failure and repeated trauma.

Description

technical field [0001] The invention relates to an experimental blood collection device, in particular to an efficient blood collection and blood collection device for the fundus of rats and mice. Background technique [0002] Fundus blood collection (blood collection from the retro-orbital venous plexus) is one of the common blood collection methods for mice. The general operation method is: fix the mouse with the left hand, pinch the skin of the head as tightly as possible to fix the head, and gently press down on both sides of the neck. Make the eyeball fully protrude (the retroorbital venous plexus is congested), hold the capillary glass tube in the right hand, and insert it along the posterior wall of the inner canthus in the direction of the larynx. When there is resistance, retreat later, keep the horizontal position, and attract a little. Due to blood pressure and capillary action, the blood will flow into the capillary glass tube. After obtaining the required blood ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/154
CPCA61B5/15003A61B5/150343A61B5/150572A61B5/150603A61B5/150946A61B5/154
Inventor 阎岩陆忠华黄利华
Owner WUXI NO 5 PEOPLES HOSPITAL
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