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Double-effect gel fever cooling patch and preparation method thereof

A technology of antipyretic patch and gel, which is applied in the field of medical products, can solve the problems that are not conducive to skin respiration and heat dissipation, affect cell secretion function, and poor air permeability of the gel, so as to achieve skin respiration and heat dissipation, strong comfort, and fast The effect of reducing fever

Inactive Publication Date: 2017-08-22
王天湶
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Although the above-mentioned cold compress gel has the effect of cold compress and cooling, it only reduces fever in a physical way, does not contain drugs, and has low efficiency
In addition, the cold compress gel is made of various glues as the matrix. The gel has poor air permeability and completely isolates the skin from the air after laying, which is not conducive to skin respiration and heat dissipation, and affects the secretory function of cells. poor comfort

Method used

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  • Double-effect gel fever cooling patch and preparation method thereof
  • Double-effect gel fever cooling patch and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] A double-effect gel antipyretic patch is prepared from the following raw materials in parts by weight:

[0034] 100 parts of seaweed extract (water content 30wt%), 400 parts of 4wt% calcium chloride solution, 5 parts of patchouli oil, 5 parts of peppermint oil, 3 parts of honeysuckle extract, 3 parts of pregelatinized starch-embedded ammonium chloride , 1 part of cellulose gum, 2 parts of sodium carboxymethyl cellulose, 50 parts of alcohol, 3 parts of sodium carbonate, and 5 parts of citric acid.

[0035] The preparation method of the above-mentioned double-effect gel antipyretic patch, the steps are as follows:

[0036] (a) Add patchouli oil, peppermint oil, honeysuckle extract, and sodium carboxymethylcellulose to the seaweed extract in sequence, and stir evenly to obtain a viscous mixed mucus.

[0037] (b) Under the conditions of low-speed stirring (150r / min) and 3°C, add sodium carbonate and citric acid to the mixed mucus successively until the mixture is evenly stir...

Embodiment 2

[0042] A double-effect gel antipyretic patch is prepared from the following raw materials in parts by weight:

[0043] 100 parts of seaweed extract (water content 30wt%), 400 parts of 4wt% calcium chloride solution, 5 parts of patchouli oil, 5 parts of peppermint oil, 3 parts of honeysuckle extract, 3 parts of pregelatinized starch-embedded ammonium chloride , 1 part of cellulose gum, 2 parts of sodium carboxymethyl cellulose, 50 parts of alcohol, 3 parts of sodium carbonate, and 5 parts of citric acid.

[0044] Wherein, the patchouli oil and peppermint oil are loaded before adding: get patchouli oil and peppermint oil; then add 0.4 times of its quality fumed hydrophobic silica powder to patchouli oil and peppermint oil, stir evenly, Get loads of treated patchouli and peppermint oils.

[0045] The preparation method of the gas-phase hydrophobic silica powder is as follows: dilute tetraethyl orthosilicate 45 times with 80wt% alcohol solution, after mixing evenly, add acetic ac...

Embodiment 3

[0053] A double-effect gel antipyretic patch is prepared from the following raw materials in parts by weight:

[0054] 90 parts of seaweed extract (water content 25wt%), 250 parts of 5wt% calcium chloride solution, 3 parts of patchouli oil, 7 parts of peppermint oil, 2 parts of honeysuckle extract, 4 parts of pregelatinized starch-embedded ammonium chloride , 0.5 parts of cellulose gum, 3 parts of sodium carboxymethyl cellulose, 40 parts of alcohol, 2 parts of sodium carbonate, and 3 parts of citric acid.

[0055] Wherein, the patchouli oil and peppermint oil are loaded before adding: get patchouli oil and peppermint oil; then add 0.3 times of its quality fumed hydrophobic silica powder to patchouli oil and peppermint oil, stir evenly, Get loads of treated patchouli and peppermint oils.

[0056] The preparation method of the gas-phase hydrophobic silica powder is as follows: dilute tetraethyl orthosilicate 40 times with 80wt% alcohol solution, after mixing evenly, add acetic ...

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Abstract

The invention relates to the field of medical products, and discloses a double-effect gel fever cooling patch and a preparation method thereof. The fever cooling patch is prepared from the following raw materials in parts by weight: 90 to 110 parts of seaweed extracting solution, 250 to 500 parts of cross-linking solution, 3 to 7 parts of patchouli oil, 3 to 7 parts of herba menthae oil, 2 to 4 parts of honeysuckle flower extract, 2 to 4 parts of ammonium chloride, 0.5 to 1.5 parts of cellulose gum, 1 to 3 parts of sodium carboxymethylcellulose, 40 to 60 parts of ethyl alcohol, 2 to 4 parts of sodium carbonate and 3 to 6 parts of citric acid. The fever cooling patch disclosed by the invention contains both physical and medicinal fever cooling components, so quick fever cooling can be realized; besides, the fever cooling patch disclosed by the invention has better breathability, and is beneficial to skin breathing and cooling, and the feeling of comfort is strong.

Description

technical field [0001] The invention relates to the field of medical products, in particular to a double-effect gel antipyretic patch and a preparation method thereof. Background technique [0002] When you have a fever, there are generally three ways to choose from: injection medicine, internal medicine and external medicine. Relatively speaking, injection medicine and internal medicine are smaller and faster, but for children or infants, the above two methods are not convenient enough . Generally, it is administered by means of topical drugs. For topical medicines for reducing fever, there are products such as antipyretic tablets and antipyretic patches on the market. Some use a film as a substrate, and some use a hydrogel as a substrate. Antipyretic tablets and antipyretic patches can clear away heat and reduce fever for patients. [0003] Patent CN201610128984.0 discloses a cold compress gel, which is made by mixing the following component raw materials according to ...

Claims

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Application Information

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IPC IPC(8): A61K36/534A61K9/06A61K47/46A61P29/00A61K33/20
CPCA61K9/0014A61K9/06A61K33/20A61K36/355A61K36/532A61K36/534A61K47/46A61K2300/00
Inventor 王天湶
Owner 王天湶