Packaged light micro flow micro cavity biochemical sensor with radial higher order mode kept

A high-order mode and sensor technology, applied in the field of sensors, to achieve strong anti-interference, good stability, and compact structure

Active Publication Date: 2017-09-01
FUDAN UNIV
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  • Abstract
  • Description
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Problems solved by technology

However, the traditional all-encapsulation packaging method will make the radial high-order modes in the microcavity disappear. Therefore, we propose a new packag

Method used

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  • Packaged light micro flow micro cavity biochemical sensor with radial higher order mode kept
  • Packaged light micro flow micro cavity biochemical sensor with radial higher order mode kept
  • Packaged light micro flow micro cavity biochemical sensor with radial higher order mode kept

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Embodiment

[0021] Example: Specific recognition of biomolecules using the encapsulated optical microfluidic biochemical sensor

[0022] 1. The measurement wavelength used is around 780nm.

[0023] 2. The diameter of the fused tapered fiber is 3 μm, which rests on the microfluidic microcavity, that is, the coupling distance is 0 μm.

[0024] 3. The microcavity is an optical microfluidic microbubble microcavity, such as figure 1 As shown, the diameter of the microcavity is about 350 μm, and the wall thickness is 4 μm.

[0025] 4. The low refractive index packaging material is MY133 polymer with a refractive index of 1.33. Since this encapsulation technique keeps the microcavity still in air, radial higher-order modes in the microcavity can be preserved, such as figure 2 As shown, the microcavity sensor still has a clear mode transmission spectrum after 24 hours of encapsulation due to the firm and anti-interference encapsulation structure.

[0026] 5. Typical resonant modes and their ...

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Abstract

The invention belongs to the technical field of sensors, and particularly relates to a packaged light micro flow micro cavity biochemical sensor with a radial higher order mode kept, which comprises a section of tapered fiber, a light micro flow micro bubble cavity, a cover slip, an ultraviolet adhesive for packaging and fixing and a low-refractive index polymer, wherein the main component of the light micro flow micro cavity is silicon dioxide, the diameter is 100-500 micrometer and the wall thickness is 2-20 micrometer; the main component of the tapered fiber is silicon dioxide, the diameter is 2-5 micrometer, and the tapered fiber is used for exciting an echo wall mode in the micro cavity; and the low-refractive index polymer has a refractive index of 1-1.4 for fixing two ends of the tapered fiber and preventing light leakage. The device carries out sensing through monitoring the displacement condition of an optical mode resonance wavelength, and has the advantages of compact structure, small size, strong anti-interference performance, good stability, simple manufacturing process and low cost and the like. Besides, the device can keep the radial higher order mode in a coupled micro cavity, extremely low detection limit and extremely high sensitivity are realized, and the application prospect in the biochemical sensing field is good.

Description

technical field [0001] The invention belongs to the technical field of sensors, and in particular relates to a packaged optical microfluidic microcavity biochemical sensor capable of retaining radial high-order modes. Background technique [0002] In recent years, optical microcavity sensors have been widely used in the field of biochemical sensing due to their ultra-high sensitivity and ultra-low detection limit. Optical microcavity refers to an optical resonant cavity whose size is comparable to the wavelength of resonant light. It localizes the light field in the cavity and makes photons oscillate multiple times in the cavity, increasing the number of interactions between light and matter. It senses the presence of analytes by detecting changes in optical patterns in the cavity, and thus can be used to detect the concentration of biomolecules or chemicals. The advantages of the whispering gallery mode microcavity are high Q value, long photon lifetime, and strong interac...

Claims

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Application Information

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IPC IPC(8): G01D5/26G01N21/41
Inventor 吴翔汤婷李子豪王伯文孙弘毅徐雷刘丽英
Owner FUDAN UNIV
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