A kind of preparation method of core-shell structure

A technology of shell structure and shell structure, applied in the field of core-shell structure preparation, can solve the problems of affecting cell activity, inaccurate control of core and shell size, difficulty in making multi-layer shells, etc., and achieve the effect of ensuring survival rate
CN107261994BActive Publication Date: 2019-10-29SICHUAN REVOTEK CO LTD
1 Cites 0 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SICHUAN REVOTEK CO LTD
Publication Date
2019-10-29

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention relates to a preparation method of a core-shell structure, namely, a biological brick for biological printing (such as 3D biological printing) and tissue engineering. The method comprises the steps as follows: a) providing a hydrophobic surface, preferably, a super-hydrophobic surface; b) dropping a core material solution to the hydrophobic surface in step a) to form a droplet so as to obtain a core-shell structure on the innermost side; c) optionally, dropping the core material solution to the formed droplet surface to obtain another core-shell structure; d) optionally, dropping a wall material solution to the formed droplet surface to obtain a shell structure; e) optionally, repeating step c) and / or step d) one or more times or alternately performing step c) and step d) one or more times; f) dropping the wall material solution to the formed droplet surface to obtain a shell structure on the outermost side, wherein the core material or wall material contained in each core or shell is selected independently.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention relates to technical fields such as biomedicine, material science, bioprinting (such as 3D bioprinting), tissue engineering and the like. In particular, the present invention relates to a preparation method of a core-shell structure, which can be used for delivering active substances, or for bioprinting (such as 3D bioprinting) and tissue engineering. Background technique

[0002] The core-shell structure refers to the use of film-forming materials to encapsulate solids, liquids or gases in them to form tiny containers with a diameter of tens of microns to thousands of microns. The material used to form the core layer is called the core material (or capsule) Heart material), the material used to form the shell (membrane) of the outer capsule is called wall material (or called encapsulation material).

[0003] At present, the main preparation methods of core-shell structure can be divided into chemical method, physical method and physicoc...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More