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Plasmon waveguide, biosensor chip and system

A plasmonic polariton and biosensing technology, applied in biological testing, material inspection products, measuring devices, etc., can solve problems such as low reliability, slow detection speed, and inability to meet the needs of in vitro diagnostic technology, so as to improve detection sensitivity, The effect of increasing signal strength

Inactive Publication Date: 2017-10-20
SHENZHEN INST OF TERAHERTZ TECH & INNOVATION +1
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  • Abstract
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Problems solved by technology

[0003] However, the detection methods of existing in vitro diagnostic technologies are usually based on the traditional Turbidimetricinhibition immunoassay or real-time quantitative gene amplification fluorescent detection system (QPCR, Real-timeQuantitative PCR Detecting System) technology, the detection sensitivity is low and the detection speed is low. Slow, low reliability, unable to meet the growing demand for in vitro diagnostic technology

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  • Plasmon waveguide, biosensor chip and system
  • Plasmon waveguide, biosensor chip and system
  • Plasmon waveguide, biosensor chip and system

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Embodiment Construction

[0024] In order to enable those skilled in the art to better understand the solutions of the present invention, the technical solutions in the embodiments of the present invention will be clearly described below in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are the embodiment of the present invention. Some examples, but not all examples. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts shall fall within the protection scope of the present invention.

[0025] The terms "comprising" and any variations thereof in the description and claims of the present invention and the above drawings are intended to cover non-exclusive inclusion. For example, a process, method or system, product or device comprising a series of steps or units is not limited to the listed steps or units, but optionally also inc...

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Abstract

The embodiment of the invention provides a plasmon waveguide, a biosensor chip and a system. Specifically, the plasmon waveguide is applied in the biosensor chip, and comprises a substrate and a plasmon structure disposed on the upper surface of the substrate, the plasmon structure includes a plurality of plasmons in periodic arrangement, the plasmons are metal split rings, and the annular openings of the plasmons are used for fixation of antibody probes. According to the embodiment of the invention, the plasmon waveguide is disposed in the biosensor chip, and the antibody probes can be used for capture of target biomolecules in detection liquid flowing into a microfluidic channel, and the plasmon waveguide is employed to enhance the signal strength of THz wave emitted to the biosensor chip, thus enhancing the signal strength of reflection THz wave detected by a terahertz analyzer, and improving the detection sensitivity, signal-to-noise ratio and reliability.

Description

technical field [0001] The embodiments of the present invention belong to the technical field of in vitro diagnosis, and in particular relate to a plasmon waveguide, a biosensing chip and a system. Background technique [0002] In vitro diagnostic technology, collectively referred to as IVD (In-VitroDiagnostics) technology internationally, refers to products and services that obtain clinical diagnostic information by testing human blood and other tissues and secretions outside the human body. Worldwide, with the rise of new technologies and the improvement of medical security policies, in vitro diagnostic technology has become one of the fastest growing directions in the biomedical industry. In vitro diagnostic technology and products have a short R&D cycle and many categories. In addition to clinical application, they can also be extended to food safety testing, animal and plant disease monitoring and other fields. They are hot spots for innovation and entrepreneurship in t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/3581G01N21/3577G01N21/55G01N33/53G01N33/543
CPCG01N21/3577G01N21/3581G01N21/55G01N33/5302G01N33/543G01N2201/0407G01N33/54373G01N21/553
Inventor 韩琳潘奕丁庆刘荣跃李辰
Owner SHENZHEN INST OF TERAHERTZ TECH & INNOVATION
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