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Honeysuckle antibacterial composition, preparation method, and application thereof

An antibacterial composition, honeysuckle extract technology, applied in the field of natural medicine preparation, can solve problems such as immature market, achieve high safety, solve skin infection, and good biocompatibility

Inactive Publication Date: 2017-10-24
蔡挺
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The single honeysuckle preparation has not been involved in external patches or ointments, and the market is not mature

Method used

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  • Honeysuckle antibacterial composition, preparation method, and application thereof
  • Honeysuckle antibacterial composition, preparation method, and application thereof
  • Honeysuckle antibacterial composition, preparation method, and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Embodiment 1: the preparation of honeysuckle antibacterial ointment

[0036] Honeysuckle extract 10g, stearic acid 10g, glyceryl monostearate 2.5g, glycerin 10g, potassium carbonate 0.9g, triethanolamine 0.3ml, and the balance is pure water.

[0037] The preparation method is as follows: take the matrix prepared by the emulsification method, add honeysuckle extract, mix well to obtain the honeysuckle antibacterial ointment, sterilize and seal.

Embodiment 2

[0038] Embodiment 2: the preparation of honeysuckle antibacterial gel

[0039] Honeysuckle extract 10g, glycerin 9g, carbomer 9403g, pure water 100ml, triethanolamine amount.

[0040] The preparation method is as follows: dissolve honeysuckle extract and glycerin in pure water successively to obtain a uniform solution, take Carbomer 940 and evenly disperse in the above solution, stir well, add triethanolamine to adjust the pH to 6.8-7.2, and after sterilization Encapsulation is enough.

Embodiment 3

[0041] Embodiment 3: the preparation of honeysuckle antibacterial gel ointment

[0042] Honeysuckle extract 10g, glycerin 7.7g, carbomer C-934 2.4g, PVP 6g, gelatin 0.5g, appropriate amount of triethanolamine, and the balance is pure water.

[0043] The preparation method is as follows: soak the carbomer with 3 times the amount of glycerin, add pure water to make a 3% concentration of carbomer gel, and adjust the pH value to 7.0 with triethanolamine (I); prepare glycerin gelatin in the usual way (II) Dissolve PVP in an appropriate amount of pure water to make a 50% PVP aqueous solution (Ⅲ); mix the honeysuckle extract with Ⅰ, grind it evenly, and then add it to the mixture of Ⅱ and Ⅲ that has been preheated and mixed in a 60°C water bath. Grind and mix evenly to make a uniform paste, spread the above-mentioned evenly stirred paste on the non-woven fabric backing, press properly to make a paste of 0.25g / cm 2 , dried in an oven at 45°C-50°C until the weight of the paste is 0.10...

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PUM

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Abstract

The invention relates to a honeysuckle antibacterial composition which includes a honeysuckle extract, in effective dose, and auxiliary materials. The invention also discloses a preparation method and an application of the composition. The composition can effectively kill pathogenic bacteria, and has excellent killing effects on pathogens, such as staphylococcus aureus, escherichia coli, streptococcus hemolyticus and the like, which cause skin inflammation, antibacterial rate being not less than 60%. The honeysuckle antibacterial composition has excellent biocompatibility, is low in cytotoxicity and is high in safety, has excellent anti-inflammation and sterilization effect, is wide in available range, and also can be applied to infants and women in lactation period.

Description

technical field [0001] The invention relates to the technical field of natural medicine preparation, in particular to a honeysuckle antibacterial composition and its preparation method and application. Background technique [0002] Honeysuckle is a traditional Chinese herbal medicine and belongs to medicinal flowers. It is also called double flower, because it is the flower bud of the perennial semi-evergreen winding shrub Lonicerae Lonicerae in the Lonicera family, also known as Lonicera japonica. It is pure white when it first blooms, and turns yellow after a day or two. Honeysuckle is a heat-clearing and detoxifying medicine, sweet in nature and cold in taste, enters the lung, stomach, and heart meridians, and is mainly used for heat-toxin sores and carbuncles. Pharmacologically, honeysuckle has antibacterial effect: in vitro experiments show that flowers and vines have antibacterial effects on various pathogenic bacteria such as Staphylococcus aureus, hemolytic streptoc...

Claims

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Application Information

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IPC IPC(8): A61K36/355A61P31/04A61P31/02A61P17/00
CPCA61K36/355A61K2236/33A61K2236/53Y02A50/30
Inventor 蔡挺郑建军项灵超吴爱国张顺
Owner 蔡挺
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