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Personalized and precise MRI method

A magnetic resonance imaging and magnetic resonance technology, which is applied in the fields of nuclear magnetic resonance analysis, material analysis through resonance, image enhancement, etc., can solve problems such as difficult to predict, pre-acquired, and time-consuming

Active Publication Date: 2020-02-14
EAST CHINA NORMAL UNIV
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Problems solved by technology

2) The setting of scanning parameters is based on the inherent properties of the tissue (optional density, T1 relaxation time and T2 relaxation time), and most of the T1 / T2 relaxation times provided by existing studies are based on a large number of healthy adult samples The average value, although the adult brain is fully developed, is relatively stable under the premise of excluding pathological changes and age-related decline, but the scanning parameters set with reference to the average relaxation time cannot ensure the optimal imaging for each individual Optimal Imaging Parameters
3) The change of relaxation time mainly depends on the change of water content in brain tissue, and in the same brain, the water content in different tissues shows a nonlinear change with age, this change is particularly significant in infants and young children, and it is difficult to predict
The current imaging method used to calculate the relaxation time takes a long time during the scan, especially for the T1 relaxation time, which requires a scan of more than 30 minutes
This makes it impossible for technicians to obtain the relaxation time of the tested brain tissue in advance before setting the imaging parameters, so as to set the individualized optimal imaging parameters

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Embodiment

[0076] Step 1: Create a sample database. Collect multi-TI and multi-TE T1 and T2 weighted imaging image data of multiple (for example, 50) standard individuals, and establish a sample database of magnetic resonance characteristic attributes, including relaxation time of samples, characteristic constants, and binary images of sample tissue segmentation Contrast-optimized signal-intensity-weighted images (ie, scout images) of samples and samples. Calculation of relaxation time T1 and T2 is obtained by fitting with the following formula:

[0077] S(TI)=a+b·exp(-TI / T1)

[0078] S(TE)=c·exp(-TE / T2)

[0079] Where S is the acquired T1 or T2 weighted image signal, and a, b, c are system constants.

[0080] Step 2: Input the target data (that is, the magnetic resonance data that needs to optimize the image contrast, or recommend individualized optimization of imaging parameters), including weighted signal intensity images and imaging parameters.

[0081] Step 3: Register the targe...

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Abstract

The invention discloses a personalized and precise magnetic resonance imaging method. During the data collecting and processing procedure of the magnetic resonance imaging operation, an individual relaxation time spectrogram is deduced and individual optimization imaging parameters are recommended. In this way, a method for realizing the weak-contrast image restoration and the personalized precise scanning is achieved. Meanwhile, a large sample knowledge base comprising tissue classification and tissue relaxation characteristics is established. Through the morphological registration and the signal strength standardization, the comparability of individual data and sample data is established. Through the modes of issue recognition, coordinate positioning, signal comparison and relaxation characteristic definition, a relaxation time spectrogram which meets the individual actual condition is deduced. Through the analysis of the individual relaxation time spectrogram, imaging parameters suitable for personalized imaging are calculated. Therefore, the obtained individual relaxation time spectrogram and the imaging parameters can be used for repairing weighted images. According to the invention, the purpose of personalized and precise scanning is achieved. The repeated scanning for repeatedly modifying imaging parameters carried out in order to obtain a high-contrast image is avoided.

Description

technical field [0001] The invention relates to the technical field of magnetic resonance imaging, and is a method for realizing magnetic resonance relaxation characteristic deduction, weak contrast magnetic resonance data restoration and individualized precise magnetic resonance imaging based on the magnetic resonance sample knowledge base and the physical principles of magnetic resonance imaging. Background technique [0002] Magnetic resonance imaging is a common and important imaging diagnostic tool in medical diagnosis. The contrast of magnetic resonance images is related to the setting of scanning parameters, and the setting of scanning parameters and the mechanism of contrast generation are mainly based on the spin density between tissues, the longitudinal relaxation time T1 and the transverse relaxation time T2. At present, some work has summarized the average range of T1 / T2 relaxation time in different brain tissues under different magnetic field conditions, which p...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G06T11/00G06T7/30G06T7/143G06T7/11G01N24/08
CPCG01N24/088G06T7/11G06T7/143G06T7/30G06T11/005G06T2207/10088G06T2207/20076G06T2207/30016
Inventor 徐冬溶蒋雨薇
Owner EAST CHINA NORMAL UNIV
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