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Green plum for treating throat diseases and preparation method thereof

A technology of green plums for throat diseases, applied in the field of green plums for the treatment of throat diseases and its preparation, can solve problems such as overtreatment

Active Publication Date: 2021-07-06
SUN YAT SEN MEMORIAL HOSPITAL SUN YAT SEN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Among them, viral infection is the main cause of throat diseases. However, clinical patients are still widely treated with antibiotics, and there is a great risk of overtreatment

Method used

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  • Green plum for treating throat diseases and preparation method thereof
  • Green plum for treating throat diseases and preparation method thereof
  • Green plum for treating throat diseases and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-3

[0022] Step 1), prepare materials according to the formula shown in Table 1, take Gangmei, Platycodon grandiflorum, Radix Arisa, Radix Glycyrrhizae, Radix Achyranthes Radix, Angelica dahurica and Pinellia ginger in parts by weight, add 5 times the quality of water, decoct for 45min, filter, add the filter residue 5 times the quality of water, decoct for 45 minutes, filter, then add 5 times the quality of water to the filter residue, and decoct for 45 minutes;

[0023] Combined and concentrated to obtain the extract, the relative specific density of the extract at 60°C is 1.1;

[0024] Step 2), add sodium benzoate to the extract obtained in step 1), then add peppermint oil, peppermint essence and green plum germ, mix evenly, and after airtight storage for 72 hours, take out the green plum germ and pack it.

experiment example 1

[0036] Experimental example 1 anti-inflammatory effect drug efficacy evaluation

[0037] 1. Purpose of the experiment

[0038] Comparing the anti-inflammatory effect of each embodiment and comparative example (same dosage), provides theoretical basis for its curative effect for treating pharyngitis.

[0039] 2. Experimental principle

[0040] As a chemical inflammatory agent, xylene can cause the release of inflammatory mediators such as histamine, kinin, and fibrinolytic enzymes. The release of these mediators can cause the increase of local capillary permeability and the infiltration of inflammatory cells, resulting in acute exudative inflammatory edema of the ear. The above-mentioned inflammatory response experiment is often used to evaluate the anti-inflammatory effect of the test drug.

[0041] 3. Experimental animals and feeding conditions

[0042] 3.1 Experimental animals

[0043] Grade, breed: SPF grade Kunming mouse

[0044] Animal management: Animals are kept a...

Embodiment 1

[0091] Example 1 The high, medium and low dose groups can inhibit p-xylene-induced ear swelling in mice, and the inhibitory effect is enhanced with the increase of the drug dose. The anti-swelling effect of Comparative Example 1 and Comparative Example 2 that does not contain Araceae and Jiang Pinellia is weaker than that of the dosage group in Example 1, but still has a certain inhibitory effect. Comparative example 4 and comparative example 5 are weaker than comparative example 1 in inhibiting swelling.

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PUM

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Abstract

The invention discloses a green plum for treating throat diseases and a preparation method thereof. In step 1), 430 to 530 parts of plum, 580 to 710 parts of achyranthes bidentata, 430 to 530 parts of ginger pinellia and 430 to 530 parts of arachis are prepared according to the weight ratio , 800-1000 parts of bellflower, 1400-1700 parts of licorice, 430-530 parts of Angelica dahurica; decoct three times, filter, combine the filtrate, concentrate to obtain the extract, and the relative density of the extract is not less than 1.1 under the condition of 60 ° C; steps 2) Add 1-3 parts of preservatives to the extract, then add 80-100 parts of peppermint oil, 80-100 parts of mint essence and 16,000-20,000 parts of green plum germ, mix well, and store in airtight storage for 72 hours, then pack the green plum germ Instantly. The green plum described in this case has a better effect on treating throat discomfort.

Description

technical field [0001] The invention relates to the field of treating throat diseases, in particular to greengage for treating throat diseases and a preparation method thereof. Background technique [0002] Throat disease is a common upper respiratory system disease, mostly caused by upper respiratory tract infection. Chronic rhinitis, acute and chronic tonsillitis. Current studies believe that the main etiology is virus, bacteria and non-infectious factors (such as mouth breathing, allergic reaction, gastroesophageal reflux, smoking, alcohol, high temperature, dust, smoke, irritating gas, etc.). Among them, viral infection is the main cause of throat diseases. However, clinical patients are still widely treated with antibiotics, and there is a great risk of overtreatment. Contents of the invention [0003] In summary, it is necessary for the present invention to provide a greengage for treating throat diseases, which can effectively relieve the symptoms of sore throat a...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8888A61P11/04A61P29/00A61P31/00A23L19/00A23L33/105
CPCA23V2002/00A61K9/0056A61K36/185A61K36/21A61K36/232A61K36/346A61K36/484A61K36/736A61K36/8884A61K36/8888A61K2236/331A61K2236/39A23L19/03A23L33/105A61K2300/00A23V2200/314A23V2250/21
Inventor 伍俊妍邱凯锋刘春霞余晓霞李国成李钦海
Owner SUN YAT SEN MEMORIAL HOSPITAL SUN YAT SEN UNIV
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