Extracting technology of flavone of ageratum conyzoides by using response surface methodology and application thereof

Abstract

The invention discloses an extracting technology of flavone of ageratum conyzoides by using response surface methodology and application thereof. According to the design principle of Box-Behnken test,the technology conditions of the flavone of the ageratum conyzoides are designed and optimized by Design-Expert software, such as concentration of ethyl alcohol, extracting time, material and liquidratio, and extracting frequency; the flavone of the ageratum conyzoides is extracted in an ultrasonic-assisted way. The extracting technology specifically comprises the following steps of drying the ageratum conyzoides, and crushing into powder; adding the ageratum conyzoides powder into an extracting tank, mixing with the ethyl alcohol solution, and performing ultrasonic extracting; placing an extracting solution into a rotary evaporator, relieving pressure and distilling, and ventilating air to volatize the solvent; evaporating by water bath, so as to obtain the finished product of the flavone of the ageratum conyzoides. The extracting technology has the advantages that the extracting rate is high; the anti-oxidizing ability of the extracted flavone of the ageratum conyzoides is strong;the stronger application effect is realized in anti-oxidizing medicines and food antioxidants.

Description

【Technical field】 [0001] The invention belongs to the technical field of extraction of medicinal plant active ingredients and food additives, and in particular relates to a response surface method to optimize the extraction process of ageratum flavonoids and its application. 【Background technique】 [0002] Ageratum Conyzoides L., also known as red thistle, salty shrimp flower, white flower grass, anti-inflammatory grass, stink grass, etc., is an annual herb of the genus Ageratum Conyzoides in the family Asteraceae. The introduction into my country is now widely distributed in the provinces south of the Yangtze River. Included in the local standards of traditional Chinese medicinal materials in various provinces in southern my country [0003] Ageratum has the functions of clearing away heat, detoxifying, stopping bleeding, and relieving pain. It is a traditional folk medicinal plant in various countries in the world. It has a history of traditional medicinal use in Asia, Af...

AI Technical Summary

Problems solved by technology

[0005] From the literature on the analysis of the chemical components of Ageratum thistle, it is found that it is rich in flavonoids and terpenes, which are the most effective anti-oxidation components of traditional Chinese medicine. A report on the study of its antioxidant effect

Especially in my country, ageratum has been treated as a weed, and its research only stays in the aspect of agricultural allelopathy, but there is little research on the efficacy of ageratum.

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