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Composition for treating acne and external gel thereof as well as preparation method of external gel

A technology of external gel and composition, applied in the field of medicine, can solve problems such as skin irritation and drug resistance, and achieve the effects of extending the industrial chain, high transdermal efficiency and non-toxic effect.

Active Publication Date: 2018-03-06
XIAN MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The object of the present invention is to provide a composition for the treatment of acne, which solves the problems of skin irritation and drug resistance in the topical administration of the acne treatment regimen

Method used

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  • Composition for treating acne and external gel thereof as well as preparation method of external gel
  • Composition for treating acne and external gel thereof as well as preparation method of external gel
  • Composition for treating acne and external gel thereof as well as preparation method of external gel

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0059] A composition for treating acne is composed of the following components by mass percentage: peony seed oil 29%, bletilla striata polysaccharide 54%, aloe polysaccharide 17%, and the mass percentage of the above components is 100%.

[0060] The above-mentioned external gel of the composition for treating acne is composed of the following components by mass percentage: 47% of the composition for treating acne, 31% of PEG-40 hydrogenated castor oil, 6% of polyethylene glycol 400, carbomer 16 %, the sum of the mass percentages of the above components is 100%.

[0061] The preparation method of the external gel of the above-mentioned composition for treating acne is specifically implemented according to the following steps:

[0062] Step 1, weighed respectively by mass percentage: 47% of the composition for treating acne, 31% of PEG-40 hydrogenated castor oil, 6% of polyethylene glycol 400, 16% of carbomer, the sum of the mass percentages of the above components is 100%. s...

Embodiment 2

[0072] A composition for treating acne, which consists of the following components by mass percentage: 31% of peony seed oil, 50% of bletilla striata polysaccharide, 19% of aloe polysaccharide, and the total mass percentage of the above components is 100%.

[0073] The above-mentioned external gel of the composition for treating acne is composed of the following components by mass percentage: 49% of the composition for treating acne, 29% of PEG-40 hydrogenated castor oil, 5% of polyethylene glycol 400, and 17 carbomers %, the sum of the mass percentages of the above components is 100%.

[0074] The preparation method of the external gel of the above-mentioned composition for treating acne is specifically implemented according to the following steps:

[0075] Step 1, weighed respectively by mass percentage: 49% of the composition for treating acne, 29% of PEG-40 hydrogenated castor oil, 5% of polyethylene glycol 400, 17% of carbomer, the sum of the mass percentages of the above...

Embodiment 3

[0085] A composition for treating acne, which consists of the following components by mass percentage: 33% of peony seed oil, 48% of bletilla striata polysaccharide, 19% of aloe polysaccharide, and the total mass percentage of the above components is 100%.

[0086] The above-mentioned external gel of the composition for treating acne is composed of the following components by mass percentage: 47% of the composition for treating acne, 31% of PEG-40 hydrogenated castor oil, 5% of polyethylene glycol 400, carbomer 17 %, the sum of the mass percentages of the above components is 100%.

[0087] The preparation method of the external gel of the above-mentioned composition for treating acne is specifically implemented according to the following steps:

[0088] Step 1, weighed respectively by mass percentage: 47% of the composition for treating acne, 31% of PEG-40 hydrogenated castor oil, 5% of polyethylene glycol 400, 17% of carbomer, the sum of the mass percentages of the above comp...

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Abstract

The invention discloses a composition for treating acne. The composition is prepared from the following components in percentage by mass: 29 to 33 percent of peony seed oil, 48 to 54 percent of bletilla striata polysaccharide and 15 to 19 percent of aloe polysaccharide, wherein the sum of the mass percent of all the components is 100 percent. The invention also discloses the external gel of the composition and a preparation method of the external gel. The composition for treating the acne, disclosed by the invention, is based on the compatibility theory of traditional Chinese medicine and is prepared by selecting the peony seed oil, the bletilla striata polysaccharide and the aloe polysaccharide as raw materials; meanwhile, a preparation of the composition, namely nano emulsion gel, with the characteristics of high penetration efficiency and delayed release is obtained. The drawbacks of skin irritation and drug resistance in existing local administration of the acne are overcome; in addition, the composition has the characteristics of safety, no toxicity and good effects; meanwhile, comprehensive utilization of oil peony, bletilla striata polysaccharide and aloe resources is improved, the industrial chain is extended and certain social benefits are produced.

Description

technical field [0001] The invention belongs to the technical field of medicine and relates to a composition for treating acne, and also relates to an external gel of the composition and a preparation method of the external gel. Background technique [0002] Acne, commonly known as whelk and acne, is a common disease in dermatology. About 85% of people in adolescence have suffered from acne to varying degrees. On the one hand, it affects the appearance of the patient, and even has a serious impact on the psychology. Modern studies have shown that there are many causes of acne, including sex hormone secretion, microbial infection, inflammatory damage, and immune disorders. Oral administration and topical administration are mostly used in the treatment plan, among which retinoic acid drugs and antibacterial drugs are mostly used in topical administration. Although the skin damage of patients has been significantly alleviated, there are problems of skin irritation and drug resi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/71A61K36/65A61P17/10A61K9/06A61K31/715
CPCA61K9/0014A61K9/06A61K31/715A61K36/65A61K36/71A61K2300/00
Inventor 陈程刘瑞罗国平闫梦茹张存劳
Owner XIAN MEDICAL UNIV
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