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Coated sustained-release agent of small-molecular organic acid type acid preparation

A small molecule organic acid and slow-release agent technology, which is applied in the molding or processing of animal feed, additional food elements, animal feed, etc., can solve the problems of active ingredient destruction, agglomeration, and potency reduction, etc., and achieve the purpose of strengthening the intestinal tract Antibacterial effect, large-scale breeding benefits, and the effect of reducing intestinal pH

Inactive Publication Date: 2018-03-23
WEIFANG JIAYIJIA BIO TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0019] Ordinary mixed acidity regulators, whose active ingredients are often directly exposed to the outside world, contact with other substances after being added to the feed, and are easy to react with other substances, causing feed heating, caking and other undesirable phenomena, and causing damage to active ingredients and lower potency And other issues

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] A small molecule organic acid type acid preparation coated sustained-release agent, which is made of the following parts by weight of raw materials: formic acid 25, ammonia 15, lactic acid 15, acetic acid 7, citric acid 7, propionic acid 3, fumaric acid 3. Silica 25, Glyceryl Monostearate 20, Ethanol 15.

[0038] The production steps of the above acid preparation are as follows:

[0039] (1) Put the formic acid in a stainless steel reactor (with temperature control);

[0040] (2) Slowly pour ammonia into the formic acid from the bottom up, and ensure that the temperature is maintained at 75°C;

[0041] (3) After the reaction is complete, add citric acid, propionic acid, lactic acid, acetic acid, and fumaric acid, dissolve, stir for 25 minutes and mix well;

[0042] (4) After cooling down to room temperature, spray the liquid onto the silica carrier to form a granular core material;

[0043] (5) Mix glyceryl monostearate and ethanol to make spray wall material; the thickness of th...

Embodiment 2

[0048] A small molecule organic acid type acid preparation coated sustained-release agent, made of the following parts by weight of raw materials: formic acid 20, ammonia 10, lactic acid 10, acetic acid 5, citric acid 5, propionic acid 1, fumaric acid 2, Silica 20, glyceryl monostearate 10, ethanol 5.

[0049] The production steps of the above acid preparation are as follows:

[0050] (1) Put the formic acid in a stainless steel reactor (with temperature control);

[0051] (2) Slowly pour ammonia into the formic acid from the bottom up, and ensure that the temperature is maintained at 60°C;

[0052] (3) After the reaction is complete, add citric acid, propionic acid, lactic acid, acetic acid, and fumaric acid, dissolve, stir for 20 minutes and mix well;

[0053] (4) After cooling down to room temperature, spray the liquid onto the silica carrier to form a granular core material;

[0054] (5) Mix glyceryl monostearate and ethanol to make spray wall material; the thickness of the packagin...

Embodiment 3

[0059] A small-molecule organic acid type acid preparation coated sustained-release agent, made of the following parts by weight of raw materials: formic acid 30, ammonia 20, lactic acid 20, acetic acid 10, citric acid 10, propionic acid 5, fumaric acid 5, Silica 30, glyceryl monostearate 30, ethanol 20.

[0060] The production steps of the above acid preparation are as follows:

[0061] (1) Put the formic acid in a stainless steel reactor (with temperature control);

[0062] (2) Slowly pour ammonia into the formic acid from the bottom up, and ensure that the temperature is maintained at 60-90°C;

[0063] (3) After the reaction is complete, add citric acid, propionic acid, lactic acid, acetic acid, and fumaric acid, dissolve, stir for 20-30 minutes and mix well;

[0064] (4) After cooling down to room temperature, spray the liquid onto the silica carrier to form a granular core material;

[0065] (5) Mix glycerol monostearate and ethanol to make spray wall material; the thickness of the...

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Abstract

The invention discloses a coated sustained-release agent of a small-molecular organic acid type acid preparation. The coated sustained-release agent of the small-molecular organic acid type acid preparation is characterized by being prepared from the following raw materials in parts by weight: 20-30 parts of formic acid, 10-20 parts of ammonia water, 10-20 parts of lactic acid, 5-10 parts of acetic acid, 5-10 parts of citric acid, 1-5 parts of propanoic acid, 2-5 parts of fumaric acid, 20-30 parts of silicon dioxide, 10-30 parts of glyceryl monostearate and 5-20 parts of ethanol. The acid preparation component of the coated sustained-release agent is effectively separated from other materials, so the problems are avoided; the characteristic that the glyceryl monostearate is digested in theintestinal tracts is utilized, and the acid preparation component can pass through the stomach and be released in the intestinal tracts in a targeted mode, thereby effectively reducing the pH value in the intestinal tracts, enhancing the antibiotic effects of the intestinal tracts and bringing greater breeding benefit; and also the coated sustained-release agent of the small-molecular organic acid type acid preparation is a trend in the future.

Description

Technical field [0001] The invention relates to the technical field of acid preparations, in particular to a small molecule organic acid type acid preparation coated sustained-release agent and a preparation method thereof. Background technique [0002] my country's feed industry started in the middle and late 1970s. Since 1992, its feed output has leapt to the second place in the world. Since 2011, its feed output has surpassed the United States and ranked first in the world. After more than 30 years of development, my country's feed industry has formed a complete feed industry system supported by feed processing industry, feed material industry, feed additive industry, feed machinery industry, and feed scientific research and education, quality and safety. The development of the feed industry has made significant contributions to the advancement of the modern breeding industry and the improvement of people's living standards. In this rapid development process, some problems ha...

Claims

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Application Information

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IPC IPC(8): A23K20/105A23K20/158A23K20/20A23K40/30
CPCA23K20/105A23K20/158A23K20/20A23K40/30
Inventor 郭华姬长存谭福全
Owner WEIFANG JIAYIJIA BIO TECH
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