Film-forming type medical ultrasonic coupling agent and preparation and application methods thereof

A technology of ultrasonic coupling agent and conjunctiva, applied in echo/ultrasonic imaging agents, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., can solve problems such as inconvenient use, and achieve convenient use and strong integrity , the effect of simple operation

Active Publication Date: 2018-03-30
AFFILIATED YONGCHUAN HOSPITAL OF CHONGQING MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the existing ultrasonic couplant needs to be cleaned to be removed after the ultrasonic examination, which makes it inconvenient to use

Method used

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  • Film-forming type medical ultrasonic coupling agent and preparation and application methods thereof
  • Film-forming type medical ultrasonic coupling agent and preparation and application methods thereof

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Experimental program
Comparison scheme
Effect test

preparation Embodiment 1

[0033] Chinese medicinal extract of the present invention comprises the following Chinese medicinal materials in parts by weight:

[0034] 30 parts of Yang Gouhua, 35 parts of Bupleurum, 40 parts of Dichofern, 50 parts of Water Fern, 40 parts of Tang Songcao, 30 parts of Buddleia, and 60 parts of grape skin. Its preparation method is as follows:

[0035] After drying Yangzihua, Bupleurum, Trichofern, water fern, Tangsongcao, Buddleia, and grape skins, mix and pulverize them through a 60-mesh sieve to obtain a mixed powder, wrap the mixed powder into a small bag with filter paper, and then use the Concentrations of 65%, 70%, 75%, and 80% ethanol are used for gradient extraction, wherein the extraction temperature is 65°C, and the extraction time of each gradient is 20 minutes. The mixed powder and the ethanol material with a concentration of 65% and 70% The liquid ratio is 1:4, the solid-liquid ratio between the mixed powder and ethanol with a concentration of 75% and 80% is 1...

preparation Embodiment 2

[0037] 60 parts of Yang Gouhua, 60 parts of Bupleurum, 80 parts of Dichofern, 90 parts of Water Fern, 60 parts of Tang Songcao, 50 parts of Buddleia, and 90 parts of grape skin. Its preparation method is as follows:

[0038] After drying Yangzihua, Bupleurum, Trichofern, water fern, Tangsongcao, Buddleia, and grape skins, mix and pulverize them through a 60-mesh sieve to obtain a mixed powder, wrap the mixed powder into a small bag with filter paper, and then use the Concentrations of 65%, 70%, 75%, and 80% ethanol are used for gradient extraction, wherein the extraction temperature is 70°C, and the extraction time of each gradient is 40 minutes. The mixed powder and ethanol materials with a concentration of 65% and 70% The liquid ratio is 1:4, the solid-liquid ratio between the mixed powder and ethanol with a concentration of 75% and 80% is 1:2, and the filtrates of each gradient are combined after the extraction is completed. Distill at 0.06MPa-0.07MPa until there is no ref...

preparation Embodiment 3

[0040] 50 parts of Yang Gouhua, 40 parts of Bupleurum, 70 parts of Drichoptera, 60 parts of Water Fern, 50 parts of Tang Songcao, 40 parts of Buddleia, and 80 parts of grape skin. Its preparation method is as follows:

[0041]After drying Yangzihua, Bupleurum, Trichofern, water fern, Tangsongcao, Buddleia, and grape skins, mix and pulverize them through a 60-mesh sieve to obtain a mixed powder, wrap the mixed powder into a small bag with filter paper, and then use the Concentrations of 65%, 70%, 75%, and 80% ethanol are used for gradient extraction, wherein the extraction temperature is 68°C, and the extraction time of each gradient is 30 minutes. The mixed powder and the ethanol material with a concentration of 65% and 70% The liquid ratio is 1:4, the solid-liquid ratio between the mixed powder and ethanol with a concentration of 75% and 80% is 1:2, and the filtrates of each gradient are combined after the extraction is completed. Distill at 0.06MPa-0.07MPa until there is no...

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Abstract

The invention discloses a film-forming type medial ultrasonic coupling agent and preparation and application methods thereof and relates to the technical field of medial ultrasonic coupling agents. The medial ultrasonic coupling agent comprises 8-15 parts of polyvinyl alcohol, 3-5 parts of polyethylene glycol, 5-10 parts of sodium alginate, 8-15 parts of carboxymethyl chitosan, 5-10 parts of gelatin, 1-4 parts of hyaluronic acid, 6-10 parts of traditional Chinese medicine extract and 400-500 parts of deionized water, wherein the traditional Chinese medicine extract comprises Populus tomentosamale flower, radix bupleuri, dryopteris, Ceratopteris thalictroides, Thalictrum aquilegifolium, Buddleja lindleyana and grape skin. The prepared film-forming type medical coupling agent has the advantages that the medical coupling agent is good in spreadability, non-irritant to the skin, incapable of corroding an ultrasonic probe, few in bubbles, clear in imaging and excellent in lubricating performance, the whole medical coupling agent can form a film after being sprayed for a certain period of time, the whole film layer can be stripped off, the film forming time of the medical coupling agentis shortened along with the rising of environment temperature, the film layer can be stripped off after ultrasonic examination, cleaning is avoided, and operation simpleness and use convenience are achieved.

Description

technical field [0001] The invention relates to the technical field of medical ultrasonic coupling agent, in particular to a conjunctival type medical ultrasonic coupling agent and its preparation method and use method. Background technique [0002] When ultrasonic waves are incident on the interface between two different media, the greater the difference in impedance between the two media, the greater the reflection coefficient, and the less sound energy that passes through the interface into another medium. For medical ultrasound, if the probe is in "dry contact" with the skin, the ultrasonic waves emitted by the probe cannot enter the human body at all due to the strong reflection of the air layer between the two. For this reason, a certain substance must be filled between the surface of the probe and the skin to drive out the air and form a channel for the smooth and undistorted transmission of ultrasonic waves. This substance is called a medical ultrasonic coupling agen...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K49/22A61K36/87A61K9/70A61P29/00A61P31/02
CPCA61K9/7015A61K36/12A61K36/233A61K36/56A61K36/71A61K36/76A61K36/87A61K47/10A61K47/32A61K47/36A61K47/42A61K49/226A61K2236/333A61K2300/00
Inventor 张东竹
Owner AFFILIATED YONGCHUAN HOSPITAL OF CHONGQING MEDICAL UNIV
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