Skin-mucosa disinfectant for killing viruses and preparation method thereof

A disinfectant and virus technology, applied to antiviral agents, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., can solve the problems of many components and high production costs, and achieve less irritation and lower cost. The effect of low price and high safety

Inactive Publication Date: 2018-04-13
刘辉
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] The Chinese patent application number is 201110404909.X, and the name of the invention is: the patent of skin and mucous membrane disinfectant for killing viruses includes the following components: compound quaternary ammonium salt, o-phthalaldehyde, povidone iodine or other colorless iodine, sterilant, surfactant, chlorine dioxide, ethanol, chelating agent, stabilizer, essence, pH regulator, but the inventor found in practice that although the disinfectant has a better effect, it has many components and relatively high production cost. High, and some people will have side effects or irritation due to some of the components, so it is necessary to improve on this basis, and design a skin and mucous membrane disinfection with simpler components and less side effects on the basis of ensuring the effect liquid

Method used

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  • Skin-mucosa disinfectant for killing viruses and preparation method thereof
  • Skin-mucosa disinfectant for killing viruses and preparation method thereof
  • Skin-mucosa disinfectant for killing viruses and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0060] A skin and mucous membrane disinfectant for killing viruses, comprising the following components: C-12-14-16-18-alkyl dimethyl ethyl benzyl ammonium chloride (CAS number: 68391-01- 5), C12-14-alkyl dimethyl ethyl benzyl ammonium chloride (CAS number: 85409-23-0), synergist sodium carbonate (CAS number: 497-19-8), ethylenediaminetetra Disodium acetate (CAS No.: 139-33-3) and water (CAS No.: 732-18-5). Wherein, the weight percent content is:

[0061] C-12-14-16-18-alkyl dimethyl ethyl benzyl ammonium chloride 1wt%;

[0062] C12-14-alkyl dimethyl ethyl benzyl ammonium chloride 0.7wt%;

[0063] Synergist sodium carbonate 0.99wt%;

[0064] Disodium edetate 0.99wt%;

[0065] and water balance.

[0066] The present embodiment provides the preparation method of this disinfectant, comprises the steps:

[0067] (1) Add C-12-14-16-18-alkyl dimethyl ethyl benzyl ammonium chloride to 10 times the weight of water, stir at a medium speed at 35°C for 15 minutes to obtain liquid A...

Embodiment 2

[0073] A skin and mucous membrane disinfectant for killing viruses, comprising the following components: C-12-14-16-18-alkyl dimethyl ethyl benzyl ammonium chloride (CAS number: 68391-01- 5), C12-14-alkyl dimethyl ethyl benzyl ammonium chloride (CAS number: 85409-23-0), synergist sodium carbonate (CAS number: 497-19-8), ethylenediaminetetra Disodium acetate (CAS No.: 139-33-3) and water (CAS No.: 732-18-5). Wherein, the weight percent content is:

[0074] C-12-14-16-18-alkyl dimethyl ethyl benzyl ammonium chloride 4wt%;

[0075] C12-14-alkyl dimethyl ethyl benzyl ammonium chloride 3.7wt%;

[0076] Synergist sodium carbonate 0.1wt%;

[0077] Disodium edetate 0.1wt%;

[0078] and water balance.

[0079] The present embodiment provides the preparation method of this disinfectant, comprises the steps:

[0080] (1) Add C-12-14-16-18-alkyl dimethyl ethyl benzyl ammonium chloride to 15 times the weight of water, stir at a medium speed at 39°C for 25 minutes to obtain liquid A, ...

Embodiment 3

[0086] A skin and mucous membrane disinfectant for killing viruses, comprising the following components: C-12-14-16-18-alkyl dimethyl ethyl benzyl ammonium chloride (CAS number: 68391-01- 5), C12-14-alkyl dimethyl ethyl benzyl ammonium chloride (CAS number: 85409-23-0), synergist sodium carbonate (CAS number: 497-19-8), ethylenediaminetetra Disodium acetate (CAS No.: 139-33-3) and water (CAS No.: 732-18-5). Wherein, the weight percent content is:

[0087] C-12-14-16-18-Alkyl dimethyl ethyl benzyl ammonium chloride 1.5wt%;

[0088] C12-14-alkyl dimethyl ethyl benzyl ammonium chloride 1.5wt%;

[0089] Synergist sodium carbonate 0.7wt%;

[0090] Disodium edetate 0.2wt%;

[0091] and water balance.

[0092] The present embodiment provides the preparation method of this disinfectant, comprises the steps:

[0093] (1) Add C-12-14-16-18-alkyl dimethyl ethyl benzyl ammonium chloride to 12 times the weight of water, stir at a medium speed at 36°C for 18 minutes to obtain liquid A...

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Abstract

The invention discloses a skin-mucosa disinfectant for killing viruses and a preparation method thereof. The skin-mucosa disinfectant is prepared from C-12-14-16-18-alkyl dimethyl ethyl benzyl ammonium chloride, C12-14- alkyl dimethyl ethyl benzyl ammonium chloride, synergist sodium carbonate, EDTA disodium and water. The disinfectant has quick and efficient killing effect on bacteria and viruses,has the advantages of being safe, effective, little in side effect and high in interference resistance and is suitable for disinfecting wound surfaces due to animal scratch and bite and disinfectinghands, skin, mucosa and wounds.

Description

technical field [0001] The invention relates to the technical field of disinfectants, in particular to a skin and mucous membrane disinfectant for killing viruses and a preparation method thereof. Background technique [0002] As early as 1915, Jacobs reported the synthesis of quaternary ammonium salt disinfectants, and conducted research on sterilization, pointing out that this type of disinfection has a certain bactericidal ability, which opened the historical chapter of quaternary ammonium salt disinfection, but has not been recognized. people value. In 1935, German Domagk studied the relationship between the bactericidal performance and chemical structure of this type of disinfection and bacteriostasis, which aroused great interest. In the same year, Wetzel was used in clinical disinfection practice. Subsequently, people who studied this kind of disinfection drugs followed one after another, and gradually widely used in hospital skin and mucous membrane disinfection, s...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/14A61K9/08A61K47/04A61K47/18A61P31/02A61P31/04A61P31/12A61P31/14A61P31/16A61P31/18A61P31/20A61P31/22
CPCA61K9/08A61K31/14A61K47/02A61K47/183A61K2300/00Y02A50/30
Inventor 刘辉
Owner 刘辉
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