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Preparation process and method for controllable medical degradable magnesium alloy

A preparation process, magnesium alloy technology, applied in medical science, prosthesis, etc., can solve the problems of inability to maintain mechanical integrity, fast degradation of magnesium alloy, implant failure, etc., to achieve small size, high tissue stability, tissue good stability effect

Pending Publication Date: 2018-05-01
SHANDONG JIANZHU UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The main reason is that the degradation rate of magnesium alloys in the human body environment is too fast and uncontrollable, resulting in the inability of biomedical materials made of magnesium alloys to maintain the necessary mechanical integrity during service, resulting in implant failure.

Method used

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  • Preparation process and method for controllable medical degradable magnesium alloy
  • Preparation process and method for controllable medical degradable magnesium alloy
  • Preparation process and method for controllable medical degradable magnesium alloy

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Experimental program
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Effect test

Embodiment Construction

[0023] specific implementation plan

[0024] First select raw materials: select commercial pure magnesium powder with a particle size of 200 mesh. Titanium metal powder, particle size is 300 mesh. Calcium granules with a particle size of 40 mesh, metal zinc powder with a particle size of 200 mesh, and 500 milliliters of high-purity isopropanol.

[0025] The selected raw materials were placed in an argon-filled glove box (attached figure 2 Marked in 1) and weighed to prevent oxidation of the material. The ratio is: metal magnesium powder 50%, metal zinc powder 15%, metal calcium powder 15%, metal titanium powder 20%.

[0026] After the metal powders were mixed, they were mixed with 1% by weight isopropanol and stirred for 3 minutes under the protection of argon.

[0027] Subsequently, the element mixture slurry was taken out from the glove box in the sealed container and introduced into the inlet channel in the ECAP mold 2 while the outlet channel was blocked by the baffle...

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Abstract

The invention relates to a metal powder forming technology, in particular to preparation of a controllable medical degradable magnesium alloy, and can be applied to the field of biomedical materials.The invention provides a production method of compounding various processes to obtain metal powder solidified materials of different grain sizes to ensure plasticity. Under the circumstance of good processing manufacturability, nanometer intensifying of the material is achieved, and the strength of the material as a medical stent material is guaranteed. Furthermore, according to the actual demandin the period, the degrading period of the material is adjusted by adjusting the grain sizes, so that degradation of the magnesium alloy in body fluids is controlled more reliably and efficiently.

Description

technical field [0001] The invention relates to a metal powder forming technology, in particular to the preparation of a controllable medical degradable magnesium alloy, which can be applied to the field of biomedical materials. Background technique [0002] Magnesium is one of the indispensable mineral elements in the human body. It can participate in a series of metabolic processes in the body. The density of magnesium and its alloys is about 1.74, which is close to the bone density of human compact bone at 1.75; magnesium has high specific strength and specific stiffness, elasticity The modulus is 45ga.he is similar to the mechanical properties of human bones, which can effectively reduce the stress effect; magnesium can be gradually degraded in the body, and it is easy to generate magnesium ions in the solution containing chloride ions, which are absorbed by the surrounding body tissues, or passed out of the body through body fluids. In fact, in the research field of bio...

Claims

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Application Information

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IPC IPC(8): C22C1/04C22C23/00B22F3/18A61L27/04
CPCA61L27/047C22C1/0408C22C23/00B22F3/18
Inventor 徐淑波孟子翔刘鹏
Owner SHANDONG JIANZHU UNIV
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