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Preparation with protective effect on chemical liver injury and preparation method thereof

A technology of chemical liver injury and protective effect, applied in the field of health care products, can solve problems such as poor curative effect, and achieve the effect of simple production process, convenient clinical application, and large drug loading capacity

Active Publication Date: 2021-04-02
GUIZHOU RUIHE PHARMA CO LTD LONGLI PHARMA FACTORY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Among the existing products, therefore, most of the existing products are composed of several or more medicinal materials with hepatoprotective effect, and the curative effect is not good enough

Method used

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  • Preparation with protective effect on chemical liver injury and preparation method thereof
  • Preparation with protective effect on chemical liver injury and preparation method thereof
  • Preparation with protective effect on chemical liver injury and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0126] Example 1: A granule with protective effect on chemical liver injury

[0127] Pass the pueraria root extract, Hovenia dulcis fruit extract, mulberry fruit extract, Schisandra fruit extract microcrystalline fiber and magnesium stearate through a 60-mesh sieve respectively, and weigh 100 g of the pueraria root extract and 50 g of Hovenia dulcis fruit extract after the aforementioned sieving 100g of mulberry fruit extract, 30g of schisandra extract, 100g of microcrystalline cellulose, and 1g of magnesium stearate were mixed for 25 minutes, and 57.2g of 80% ethanol was added to make a soft material, granulated through a 18-mesh sieve, dried, and 18-mesh Sieve and granulate to obtain granules. For the protection of chemical liver damage, take 2-3 times a day, 5-10g each time.

Embodiment 2

[0128] Example 2: A granule that has a protective effect on chemical liver injury

[0129] Pass Pueraria root extract, Hovenia dulcis fruit extract, mulberry extract, Schisandra fruit extract, microcrystalline cellulose and magnesium stearate through 80 mesh sieves respectively, weigh 300 g of pueraria root extract and Hovenia dulcis fruit extract after the aforementioned sieving 150g of mulberry fruit, 200g of mulberry fruit extract, 100g of schisandra chinensis extract and 200g of microcrystalline cellulose, 10g of magnesium stearate mixed for 35 minutes, added 80% ethanol of 240g to make soft material, crossed 18 mesh sieves and granulated, dried, 18 Mesh sieve for granulation to obtain granules. For the protection of chemical liver damage, take 2-3 times a day, 5-10g each time.

Embodiment 3

[0130] Example 3: A granule that has a protective effect on chemical liver injury

[0131] Pass the pueraria root water extract, Hovenia dulcis fruit water extract, mulberry water extract, Schisandra fruit water extract, microcrystalline cellulose and magnesium stearate through a 70-mesh sieve respectively, and weigh 180 g of the pueraria root water extract after the aforementioned sieving , Hovenia dulcis fruit water extract 90g, mulberry fruit water extract 162g, Schisandra fruit water extract 60g, microcrystalline cellulose 150g and magnesium stearate 5g mix 30 minutes, add the 85% ethanol of 129.4g to make soft material, pass Granulate with 18-mesh sieve, dry, and granulate with 18-mesh sieve to obtain granules. For the protection of chemical liver damage, take 2-3 times a day, 5-10g each time.

[0132] The aforementioned pueraria root water extract, Hovenia dulcis fruit water extract, mulberry water extract, and Schisandra water extract can be prepared through the follow...

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Abstract

The invention discloses a preparation with a protecting effect on a chemical liver injury. The preparation is prepared from, by weight, 100-300 parts of extract of radix pueraiae, 50-150 parts of extract of semen hoveniae, 100-200 parts of mulberry extract and 30-100 parts of extract of fructus schizandrae. The invention further provides a preparing method of the preparation. By means of the preparation with the protecting effect on the chemical liver injury, through reasonable matching of all functional raw materials, it can be guaranteed that health care functions are effectively and fully achieved, and the safety of the preparation can also be guaranteed. A modern pharmacology study result is referred to, an advanced preparation technology is adopted, and the liver protecting effect isvery definite; aiming at the crowd suffering from the chemical liver injury, all the functional raw materials can play a synergistic effect, and the functions are strengthened; the preparation has notoxic and side effect and can be taken for a long term. The preparing method is simple, production conditions are mild and easy to implement, and through pilot scale production testing, the technologyis stable and controllable.

Description

technical field [0001] The invention relates to a preparation having a protective effect on chemical liver damage and a preparation method thereof, specifically belonging to the technical field of health care products. Background technique [0002] The liver is the largest solid organ in the human body, and each adult's liver is composed of at least 300 billion liver cells. And these liver cells contain more than 2,000 kinds of biological enzymes, which participate in various life activities of the human body. It is precisely because of the chemical action of these enzymes in the liver that the liver is called the "comprehensive chemical factory" of the human body. It is an important protective organ of the human body. Chemical liver injury refers to liver injury caused by chemical hepatotoxic substances. Common chemical hepatotoxic substances are roughly divided into three categories: one is chemical toxic substances, including directly toxic substances such as trinitroto...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/79A61K36/72A61P1/16
CPCA61K36/488A61K36/57A61K36/605A61K36/72A61K36/79A61K2236/331A61K2236/39A61K2300/00
Inventor 周欣陈华国邓青芳
Owner GUIZHOU RUIHE PHARMA CO LTD LONGLI PHARMA FACTORY