Preparation method of iodoform gelatin sponge

The technology of gelatin sponge and iodoform is applied in the field of preparation of iodoform gelatin sponge, which can solve the problems of no anti-infection, inconvenient use and the like, and achieve the effects of good sterilization and hemostasis, remarkable effect and safe use.

Inactive Publication Date: 2018-06-05
JIANGSU PROVINCE JIANERKANG MEDICAL DRESSING CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] In the prior art, there are three main disinfection products for oral surgery: 1. Gelatin sponge is widely used in oral and maxillofacial surgery for tooth extraction and jaw surgery. Inf...

Method used

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Examples

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Embodiment 1

[0015] A kind of preparation method of iodoform gelatin sponge, described method comprises the following steps: by solid-liquid ratio 30kg / m with gelatin and deionized water 3 Mix, stir and mix evenly at 75°C to obtain a gelatin solution, mix the gelatin solution with nano-carbon materials, iodoform, formaldehyde solution, and magnesium chloride at a mass ratio of 100:1:10:0.2 to obtain a mixed solution, and then store at -30°C Frozen under conditions for 8 hours, finally dried in a freeze dryer for 24 hours to obtain iodoform gelatin sponge, the mass fraction of formaldehyde solution is 30%, gelatin in this embodiment is selected from aquatic fish skin gelatin, nano-carbon material is selected from graphene, nano-carbon material The particle size is 100nm, and the iodoform gelatin sponge is also cut, sealed and packaged, and sterilized by ultraviolet light.

Embodiment 2

[0017] A kind of preparation method of iodoform gelatin sponge, described method comprises the following steps: by solid-liquid ratio 60kg / m with gelatin and deionized water 3 Mix, stir and mix evenly at 75°C to obtain a gelatin solution, mix the gelatin solution with nano-carbon materials, iodoform, formaldehyde solution, and magnesium chloride at a mass ratio of 100:3:15:1.8 to obtain a mixed solution, and then store it at -30°C Frozen under conditions for 10 hours, and finally dried in a freeze dryer for 36 hours to obtain iodoform gelatin sponge, the mass fraction of formaldehyde solution is 30%, gelatin in this embodiment is selected from aquatic fish skin gelatin, nano-carbon material is selected from graphene, nano-carbon material The particle size is 200nm, and the iodoform gelatin sponge is also cut, sealed and packaged, and sterilized by ultraviolet light.

Embodiment 3

[0019] A kind of preparation method of iodoform gelatin sponge, described method comprises the following steps: by solid-liquid ratio 75kg / m gelatin and deionized water 3 Mix, stir and mix evenly at 75°C to obtain a gelatin solution, mix the gelatin solution with nano-carbon materials, iodoform, formaldehyde solution, and magnesium chloride in a mass ratio of 100:5:20:3 to obtain a mixed solution, and then store it at -20°C Frozen under conditions for 12 hours, and finally dried in a freeze dryer for 48 hours to obtain iodoform gelatin sponge, the mass fraction of formaldehyde solution is 30%, in the present embodiment, the gelatin is selected from aquatic fish skin gelatin, the nano-carbon material is selected from graphene, and the nano-carbon material The particle size is 200nm, and the iodoform gelatin sponge is also cut, sealed and packaged, and sterilized by ultraviolet light.

[0020] The preparation method of the gelatin sponge for trauma hemostasis of the present inve...

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Abstract

The invention relates to the technical field of medical supplies, and particularly relates to a preparation method of iodoform gelatin sponge, comprising the following steps: mixing gelatin with deionized water according to a solid-to-liquid ratio of 30-75kg/m<3>; uniformly mixing in the condition of 75 DEG C to obtain a gelatin solution; mixing the gelatin solution with a carbon nanoparticle material, iodoform, a formaldehyde solution and magnesium chloride in a mass ratio of 100:(1-5):(10-20):(0.2-3), to obtain a mixed solution; then freezing for 8-12h in the condition of minus 30-minus 20 DEG C; and finally drying for 24-48h in a freezer dryer to obtain the iodoform gelatin sponge. The preparation method of the gelatin sponge used for trauma hemostasis is simple, green and environment-friendly, and low in manufacture cost of the selected principle; and the prepared iodoform gelatin sponge is uniform in pore size distribution, good in hydrophobic and lipophilic performances, high instrength, remarkable in the trauma hemostasis effect, and capable of well sterilizing and stopping bleeding.

Description

technical field [0001] The invention relates to the technical field of medical supplies, in particular to a preparation method of iodoform gelatin sponge. Background technique [0002] In the prior art, there are three main disinfection products for oral surgery: 1. Gelatin sponge is widely used in oral and maxillofacial surgery for tooth extraction and jaw surgery. Infection effect; 2. The iodoform gauze can be used for the treatment of tooth extraction socket wound hemostatic agent dry socket, and the iodoform gauze needs to be taken out after use, which is inconvenient to use. Contents of the invention [0003] The purpose of the present invention is: provide a kind of preparation method of iodoform gelatin sponge which is easy to use and has good hemostatic effect. [0004] In order to solve the problems of the technologies described above, the technical scheme adopted in the present invention is as follows: [0005] A kind of preparation method of iodoform gelatin s...

Claims

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Application Information

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IPC IPC(8): A61L24/10A61L24/00
CPCA61L24/0015A61L24/0036A61L24/104A61L2300/202A61L2300/404A61L2400/04C08L89/00
Inventor 陈国平
Owner JIANGSU PROVINCE JIANERKANG MEDICAL DRESSING CO LTD
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