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Drug for treating obese patient with type-2 diabetes mellitus and preparation method of drug

A technology for diabetes and obesity, applied in the field of medicines for treating obesity patients with type II diabetes and the preparation thereof, can solve problems such as damage, digestive tract reaction, inability to effectively control complications, etc., achieve weight reduction, lower blood sugar, and improve human immunity Effect

Inactive Publication Date: 2018-06-22
重庆七斛生物制药有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, it may be insufficient to control type 2 diabetes with metformin in obese patients, and long-term use of western medicine has certain side effects such as gastrointestinal reactions, liver and kidney damage, and cannot effectively control complications

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] A medicine for treating obese patients with type Ⅱ diabetes, comprising the following raw materials in parts by weight: 7 parts of panax notoginseng, 15 parts of dendrobium, 20 parts of yam, 25 parts of kudzu root, 15 parts of astragalus, 30 parts of bitter melon, 7 parts of American ginseng, and 12 parts of Eucommia , 10 parts of schisandra, 15 parts of Polygonatum odoratum, 15 parts of forsythia, 15 parts of senna, 10 parts of ginkgo biloba, 15 parts of sand garden.

[0037] The preparation method of the above-mentioned medicine for treating obese patients with type Ⅱ diabetes comprises the following steps:

[0038] S1. Take dendrobium, astragalus, Eucommia ulmoides, schisandra chinensis, ginkgo leaves, and sarcocarp, mix them, grind them, add 6 times of 70% ethanol, reflux extraction for 1 hour, filter to obtain alcohol extract, and alcohol extract filter residue for later use;

[0039] S2. Take notoginseng, yam, kudzu root, bitter melon, American ginseng, Polygonatu...

Embodiment 2

[0043] A medicine for treating obese patients with type Ⅱ diabetes, comprising the following raw materials in parts by weight: 15 parts of Panax notoginseng, 7 parts of dendrobium, 30 parts of Chinese yam, 15 parts of kudzu root, 25 parts of astragalus, 20 parts of bitter melon, 15 parts of American ginseng, and 5 parts of Eucommia , 20 parts of schisandra, 7 parts of Polygonatum odoratum, 25 parts of forsythia, 7 parts of senna leaves, 20 parts of ginkgo leaves, and 7 parts of sand garden seeds.

[0044] The preparation method of the above-mentioned medicine for treating obese patients with type Ⅱ diabetes comprises the following steps:

[0045] S1. Take dendrobium, astragalus, Eucommia ulmoides, schisandra chinensis, ginkgo leaves, and schisandra, mix them, grind them, add 10 times of 75% ethanol, reflux extraction for 2 hours, filter to obtain alcohol extract, and alcohol extract filter residue for later use;

[0046] S2. Take Panax notoginseng, yam, kudzu root, bitter melo...

Embodiment 3

[0050] A medicine for treating obese patients with type Ⅱ diabetes, comprising the following raw materials in parts by weight: 9 parts of Panax notoginseng, 10 parts of Dendrobium, 22 parts of Chinese yam, 17 parts of kudzu root, 17 parts of astragalus, 24 parts of bitter melon, 9 parts of American ginseng, and 7 parts of Eucommia , 12 parts of schisandra, 9 parts of Polygonatum odoratum, 18 parts of forsythia, 8 parts of senna leaf, 13 parts of ginkgo leaf, and 9 parts of sand garden seedlings.

[0051] The preparation method of the above-mentioned medicine for treating obese patients with type Ⅱ diabetes comprises the following steps:

[0052] S1. Take dendrobium, astragalus, Eucommia ulmoides, schisandra chinensis, ginkgo leaves, and schisandra, mix and grind, add 7 times of 70% ethanol, reflux extraction for 1.5h, filter to obtain alcohol extract, and alcohol extract filter residue for later use;

[0053] S2. Take notoginseng, yam, kudzu root, bitter melon, American ginsen...

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PUM

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Abstract

The invention discloses a drug for treating an obese patient with type-2 diabetes mellitus and a reparation method of the drug and relates to the technical field of diabetes drugs. The drug is prepared from raw materials in parts by weight as follows: 7-15 parts of radix notoginseng, 7-15 parts of herba dendrobii, 20-30 parts of rhizoma dioscoreae, 15-25 parts of radix puerariae, 15-25 parts of radix astragali, 20-30 parts of bitter gourd, 7-15 parts of American ginseng, 5-12 parts of eucommia ulmoides, 10-20 parts of fructus schizandrae, 7-15 parts of radix polygonati officinalis, 15-25 partsof fructus forsythia, 7-15 parts of folium sennae, 10-20 parts of folium ginkgo and 7-15 parts of semen astragali complanati. According to the drug for treating the obese patient with type-2 diabetesmellitus and the preparation method of the drug, multiple Chinese herbal medicinal ingredients such as the radix notoginseng, the herba dendrobii, the rhizoma dioscoreae, the radix puerariae, the radix astragali, the bitter gourd, the American ginseng, the eucommia ulmoides, the fructus schizandrae and the like are selected, weight and blood sugar of high fat diet induced diabetic rats can be reduced effectively, and furthermore, the function of reducing blood fat is realized; according to clinical application of the drug, immunity of a human body can be improved, vascular microcirculation isimproved, weight gain of the obese patient is controlled, and the drug is safe, effective and stable, has lasting efficacy and few side effects and has good research and development value.

Description

technical field [0001] The invention relates to the technical field of diabetes drugs, in particular to a drug for treating obese patients with type II diabetes and a preparation method thereof. Background technique [0002] Diabetes is a group of metabolic diseases characterized by hyperglycemia. Caused by defective insulin secretion or impaired biological action, or both. Due to the long-term existence of high blood sugar in diabetes, it leads to complications such as chronic damage and dysfunction of various tissues, especially the eyes, kidneys, heart, blood vessels, and nerves, resulting in high mortality and disability rates. [0003] The number of people with diabetes in the world is as high as 422 million, and 1 in 11 people suffer from diabetes. my country has become the world's largest diabetes country, with 1 / 3 of the world's patients, and about 1.5 million new patients each year. About 97% of patients belong to type Ⅱ diabetes, and what is more serious is that...

Claims

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Application Information

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IPC IPC(8): A61K36/8984A61P3/10A61P3/04A61P3/06
CPCA61K36/16A61K36/258A61K36/42A61K36/46A61K36/481A61K36/482A61K36/488A61K36/57A61K36/634A61K36/79A61K36/8945A61K36/8969A61K36/8984A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 王洪成
Owner 重庆七斛生物制药有限责任公司
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